Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CHANG_SERUM_RESPONSE_DN |
| Enrichment Score (ES) | 0.62575734 |
| Normalized Enrichment Score (NES) | 2.1487575 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011043326 |
| FWER p-Value | 0.0080 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 31 | 0.935 | 0.0754 | Yes |
| 2 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 49 | 0.810 | 0.1414 | Yes |
| 3 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 158 | 0.552 | 0.1791 | Yes |
| 4 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 216 | 0.473 | 0.2141 | Yes |
| 5 | CLIC2 | CLIC2 Entrez, Source | chloride intracellular channel 2 | 296 | 0.404 | 0.2417 | Yes |
| 6 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 297 | 0.403 | 0.2752 | Yes |
| 7 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 318 | 0.386 | 0.3058 | Yes |
| 8 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 330 | 0.373 | 0.3360 | Yes |
| 9 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 336 | 0.371 | 0.3664 | Yes |
| 10 | PGCP | PGCP Entrez, Source | - | 406 | 0.335 | 0.3891 | Yes |
| 11 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 414 | 0.330 | 0.4159 | Yes |
| 12 | SQLE | SQLE Entrez, Source | squalene epoxidase | 446 | 0.311 | 0.4395 | Yes |
| 13 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 523 | 0.278 | 0.4568 | Yes |
| 14 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 531 | 0.275 | 0.4791 | Yes |
| 15 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 542 | 0.272 | 0.5010 | Yes |
| 16 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 666 | 0.242 | 0.5118 | Yes |
| 17 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 783 | 0.219 | 0.5213 | Yes |
| 18 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 834 | 0.207 | 0.5347 | Yes |
| 19 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 934 | 0.190 | 0.5430 | Yes |
| 20 | PKIG | PKIG Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 1121 | 0.169 | 0.5430 | Yes |
| 21 | APOD | APOD Entrez, Source | apolipoprotein D | 1122 | 0.169 | 0.5570 | Yes |
| 22 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 1211 | 0.160 | 0.5637 | Yes |
| 23 | SLC5A3 | SLC5A3 Entrez, Source | solute carrier family 5 (inositol transporters), member 3 | 1222 | 0.159 | 0.5762 | Yes |
| 24 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 1469 | 0.137 | 0.5690 | Yes |
| 25 | CST3 | CST3 Entrez, Source | cystatin C (amyloid angiopathy and cerebral hemorrhage) | 1513 | 0.134 | 0.5769 | Yes |
| 26 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 1644 | 0.126 | 0.5776 | Yes |
| 27 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 1681 | 0.124 | 0.5852 | Yes |
| 28 | CNTNAP1 | CNTNAP1 Entrez, Source | contactin associated protein 1 | 1684 | 0.124 | 0.5953 | Yes |
| 29 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 1691 | 0.123 | 0.6051 | Yes |
| 30 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1803 | 0.117 | 0.6064 | Yes |
| 31 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 1830 | 0.115 | 0.6140 | Yes |
| 32 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 1897 | 0.112 | 0.6183 | Yes |
| 33 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 1998 | 0.108 | 0.6197 | Yes |
| 34 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 2036 | 0.106 | 0.6258 | Yes |
| 35 | AXIN2 | AXIN2 Entrez, Source | axin 2 (conductin, axil) | 2363 | 0.093 | 0.6089 | No |
| 36 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 2423 | 0.091 | 0.6120 | No |
| 37 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 2435 | 0.090 | 0.6187 | No |
| 38 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 3039 | 0.070 | 0.5790 | No |
| 39 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 3238 | 0.064 | 0.5695 | No |
| 40 | WBP2 | WBP2 Entrez, Source | WW domain binding protein 2 | 3366 | 0.061 | 0.5650 | No |
| 41 | CTSF | CTSF Entrez, Source | cathepsin F | 3540 | 0.056 | 0.5566 | No |
| 42 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 4204 | 0.039 | 0.5099 | No |
| 43 | CAMLG | CAMLG Entrez, Source | calcium modulating ligand | 4317 | 0.037 | 0.5046 | No |
| 44 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4575 | 0.033 | 0.4879 | No |
| 45 | IGBP1 | IGBP1 Entrez, Source | immunoglobulin (CD79A) binding protein 1 | 4832 | 0.027 | 0.4709 | No |
| 46 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 5070 | 0.023 | 0.4549 | No |
| 47 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 5513 | 0.014 | 0.4228 | No |
| 48 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 5523 | 0.014 | 0.4233 | No |
| 49 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 5820 | 0.009 | 0.4017 | No |
| 50 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 5880 | 0.008 | 0.3979 | No |
| 51 | TNFSF12 | TNFSF12 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 12 | 6483 | -0.003 | 0.3527 | No |
| 52 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 6592 | -0.005 | 0.3451 | No |
| 53 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 6718 | -0.007 | 0.3363 | No |
| 54 | SFTPB | SFTPB Entrez, Source | surfactant, pulmonary-associated protein B | 6951 | -0.011 | 0.3197 | No |
| 55 | F10 | F10 Entrez, Source | coagulation factor X | 7144 | -0.015 | 0.3065 | No |
| 56 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7323 | -0.018 | 0.2946 | No |
| 57 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 7965 | -0.031 | 0.2488 | No |
| 58 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 8056 | -0.032 | 0.2447 | No |
| 59 | MBP | MBP Entrez, Source | myelin basic protein | 8096 | -0.033 | 0.2445 | No |
| 60 | PTPRU | PTPRU Entrez, Source | protein tyrosine phosphatase, receptor type, U | 8180 | -0.035 | 0.2412 | No |
| 61 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 8654 | -0.044 | 0.2092 | No |
| 62 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | 0.2107 | No |
| 63 | LUM | LUM Entrez, Source | lumican | 8919 | -0.050 | 0.1973 | No |
| 64 | GLS | GLS Entrez, Source | glutaminase | 9073 | -0.053 | 0.1902 | No |
| 65 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 9354 | -0.059 | 0.1741 | No |
| 66 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 9897 | -0.074 | 0.1393 | No |
| 67 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 9971 | -0.076 | 0.1401 | No |
| 68 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 10104 | -0.079 | 0.1367 | No |
| 69 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 10301 | -0.084 | 0.1290 | No |
| 70 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 10414 | -0.088 | 0.1278 | No |
| 71 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 10782 | -0.100 | 0.1085 | No |
| 72 | ZNF219 | ZNF219 Entrez, Source | zinc finger protein 219 | 11689 | -0.137 | 0.0516 | No |
| 73 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 12040 | -0.160 | 0.0385 | No |
| 74 | CCNL2 | CCNL2 Entrez, Source | cyclin L2 | 12521 | -0.201 | 0.0191 | No |
| 75 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12847 | -0.253 | 0.0157 | No |
| 76 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | 0.0353 | No |
