Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CHIARETTI_T_ALL |
| Enrichment Score (ES) | 0.5166688 |
| Normalized Enrichment Score (NES) | 1.9429597 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.00831276 |
| FWER p-Value | 0.323 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 3 | 1.622 | 0.0643 | Yes |
| 2 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 11 | 1.276 | 0.1146 | Yes |
| 3 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 21 | 1.039 | 0.1552 | Yes |
| 4 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 25 | 0.995 | 0.1946 | Yes |
| 5 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 31 | 0.935 | 0.2314 | Yes |
| 6 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 50 | 0.810 | 0.2622 | Yes |
| 7 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 51 | 0.809 | 0.2944 | Yes |
| 8 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 60 | 0.762 | 0.3241 | Yes |
| 9 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 73 | 0.715 | 0.3517 | Yes |
| 10 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 82 | 0.687 | 0.3784 | Yes |
| 11 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 164 | 0.541 | 0.3938 | Yes |
| 12 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 190 | 0.499 | 0.4118 | Yes |
| 13 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.4285 | Yes |
| 14 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 257 | 0.432 | 0.4428 | Yes |
| 15 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 314 | 0.388 | 0.4540 | Yes |
| 16 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 336 | 0.371 | 0.4672 | Yes |
| 17 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 364 | 0.357 | 0.4793 | Yes |
| 18 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 393 | 0.340 | 0.4907 | Yes |
| 19 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 507 | 0.282 | 0.4934 | Yes |
| 20 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 662 | 0.243 | 0.4914 | Yes |
| 21 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 725 | 0.231 | 0.4959 | Yes |
| 22 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 764 | 0.223 | 0.5019 | Yes |
| 23 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 824 | 0.209 | 0.5057 | Yes |
| 24 | FXYD2 | FXYD2 Entrez, Source | FXYD domain containing ion transport regulator 2 | 960 | 0.187 | 0.5029 | Yes |
| 25 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 1025 | 0.179 | 0.5052 | Yes |
| 26 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 1082 | 0.173 | 0.5078 | Yes |
| 27 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 1241 | 0.157 | 0.5021 | Yes |
| 28 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.5064 | Yes |
| 29 | S100A4 | S100A4 Entrez, Source | S100 calcium binding protein A4 | 1285 | 0.152 | 0.5111 | Yes |
| 30 | CTSH | CTSH Entrez, Source | cathepsin H | 1401 | 0.143 | 0.5081 | Yes |
| 31 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 1423 | 0.141 | 0.5121 | Yes |
| 32 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 1508 | 0.134 | 0.5111 | Yes |
| 33 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1627 | 0.127 | 0.5072 | Yes |
| 34 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 1689 | 0.123 | 0.5075 | Yes |
| 35 | RUNX3 | RUNX3 Entrez, Source | runt-related transcription factor 3 | 1723 | 0.121 | 0.5098 | Yes |
| 36 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 1736 | 0.120 | 0.5137 | Yes |
| 37 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 1760 | 0.119 | 0.5167 | Yes |
| 38 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 1829 | 0.115 | 0.5161 | No |
| 39 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 2035 | 0.106 | 0.5048 | No |
| 40 | PDLIM1 | PDLIM1 Entrez, Source | PDZ and LIM domain 1 (elfin) | 2149 | 0.101 | 0.5003 | No |
| 41 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 2298 | 0.096 | 0.4929 | No |
| 42 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 2490 | 0.088 | 0.4819 | No |
| 43 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 2561 | 0.085 | 0.4800 | No |
| 44 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 2584 | 0.084 | 0.4816 | No |
| 45 | RCBTB2 | RCBTB2 Entrez, Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 2710 | 0.080 | 0.4754 | No |
| 46 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 2816 | 0.077 | 0.4705 | No |
| 47 | CD2 | CD2 Entrez, Source | CD2 molecule | 2852 | 0.076 | 0.4708 | No |
| 48 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 2894 | 0.074 | 0.4707 | No |
| 49 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 2964 | 0.072 | 0.4683 | No |
| 50 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 3048 | 0.070 | 0.4648 | No |
| 51 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 3103 | 0.068 | 0.4634 | No |
| 52 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3202 | 0.066 | 0.4586 | No |
| 53 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3280 | 0.063 | 0.4553 | No |
| 54 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3281 | 0.063 | 0.4578 | No |
| 55 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 3286 | 0.063 | 0.4600 | No |
| 56 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 3472 | 0.058 | 0.4483 | No |
| 57 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.4502 | No |
| 58 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 3506 | 0.057 | 0.4505 | No |
| 59 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 3710 | 0.052 | 0.4372 | No |
| 60 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 3726 | 0.052 | 0.4381 | No |
| 61 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 3822 | 0.050 | 0.4329 | No |
| 62 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 3963 | 0.045 | 0.4241 | No |
| 63 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 4025 | 0.044 | 0.4212 | No |
| 64 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 4063 | 0.043 | 0.4201 | No |
| 65 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 4248 | 0.038 | 0.4077 | No |
| 66 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 4277 | 0.038 | 0.4071 | No |
| 67 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 4454 | 0.035 | 0.3952 | No |
| 68 | ST18 | ST18 Entrez, Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 4497 | 0.034 | 0.3933 | No |
| 69 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 4630 | 0.031 | 0.3846 | No |
| 70 | SLC4A1 | SLC4A1 Entrez, Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 4796 | 0.028 | 0.3732 | No |
| 71 | CD8A | CD8A Entrez, Source | CD8a molecule | 5015 | 0.024 | 0.3576 | No |
| 72 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 5152 | 0.021 | 0.3482 | No |
| 73 | IL12A | IL12A Entrez, Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 5188 | 0.020 | 0.3464 | No |
| 74 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 5264 | 0.019 | 0.3414 | No |
| 75 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 5384 | 0.017 | 0.3331 | No |
| 76 | SNF1LK | SNF1LK Entrez, Source | SNF1-like kinase | 5650 | 0.012 | 0.3135 | No |
| 77 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5660 | 0.012 | 0.3133 | No |
| 78 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 5880 | 0.008 | 0.2970 | No |
| 79 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5909 | 0.007 | 0.2952 | No |
| 80 | CD97 | CD97 Entrez, Source | CD97 molecule | 5995 | 0.005 | 0.2889 | No |
| 81 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 5997 | 0.005 | 0.2891 | No |
| 82 | CD52 | CD52 Entrez, Source | CD52 molecule | 6024 | 0.005 | 0.2873 | No |
| 83 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 6062 | 0.004 | 0.2846 | No |
| 84 | ZBTB16 | ZBTB16 Entrez, Source | zinc finger and BTB domain containing 16 | 6337 | -0.001 | 0.2639 | No |
| 85 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 6379 | -0.001 | 0.2609 | No |
| 86 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 6393 | -0.002 | 0.2599 | No |
| 87 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6502 | -0.004 | 0.2519 | No |
| 88 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 6756 | -0.008 | 0.2331 | No |
| 89 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6785 | -0.009 | 0.2313 | No |
| 90 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 6866 | -0.010 | 0.2256 | No |
| 91 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 6929 | -0.011 | 0.2214 | No |
| 92 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6942 | -0.011 | 0.2209 | No |
| 93 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 7051 | -0.013 | 0.2133 | No |
| 94 | CLEC11A | CLEC11A Entrez, Source | C-type lectin domain family 11, member A | 7186 | -0.016 | 0.2037 | No |
| 95 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 7341 | -0.019 | 0.1928 | No |
| 96 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 7859 | -0.028 | 0.1548 | No |
| 97 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 8468 | -0.041 | 0.1103 | No |
| 98 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 8582 | -0.043 | 0.1035 | No |
| 99 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 8733 | -0.046 | 0.0940 | No |
| 100 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 8893 | -0.050 | 0.0839 | No |
| 101 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 9118 | -0.054 | 0.0691 | No |
| 102 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 9312 | -0.058 | 0.0568 | No |
| 103 | SELL | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 9375 | -0.060 | 0.0545 | No |
| 104 | CD200 | CD200 Entrez, Source | CD200 molecule | 9392 | -0.060 | 0.0557 | No |
| 105 | AQP3 | AQP3 Entrez, Source | aquaporin 3 (Gill blood group) | 9501 | -0.063 | 0.0500 | No |
| 106 | RAP2B | RAP2B Entrez, Source | RAP2B, member of RAS oncogene family | 9555 | -0.064 | 0.0485 | No |
| 107 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 9625 | -0.066 | 0.0459 | No |
| 108 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 9762 | -0.069 | 0.0384 | No |
| 109 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 9987 | -0.076 | 0.0245 | No |
| 110 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 9991 | -0.076 | 0.0273 | No |
| 111 | GARNL1 | GARNL1 Entrez, Source | GTPase activating Rap/RanGAP domain-like 1 | 10148 | -0.080 | 0.0187 | No |
| 112 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 10258 | -0.083 | 0.0137 | No |
| 113 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 10260 | -0.083 | 0.0170 | No |
| 114 | LAT | LAT Entrez, Source | linker for activation of T cells | 10563 | -0.092 | -0.0023 | No |
| 115 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 10654 | -0.095 | -0.0053 | No |
| 116 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 10765 | -0.099 | -0.0096 | No |
| 117 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | -0.0364 | No |
| 118 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 11205 | -0.116 | -0.0336 | No |
| 119 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 11461 | -0.127 | -0.0478 | No |
| 120 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 11506 | -0.129 | -0.0460 | No |
| 121 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 11943 | -0.153 | -0.0730 | No |
| 122 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 11961 | -0.154 | -0.0681 | No |
| 123 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 12139 | -0.167 | -0.0749 | No |
| 124 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 12217 | -0.173 | -0.0738 | No |
| 125 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.0692 | No |
| 126 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12298 | -0.179 | -0.0657 | No |
| 127 | ARID5A | ARID5A Entrez, Source | AT rich interactive domain 5A (MRF1-like) | 12420 | -0.190 | -0.0673 | No |
| 128 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 12493 | -0.198 | -0.0649 | No |
| 129 | CD69 | CD69 Entrez, Source | CD69 molecule | 12507 | -0.200 | -0.0579 | No |
| 130 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12629 | -0.215 | -0.0585 | No |
| 131 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12632 | -0.215 | -0.0501 | No |
| 132 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 12653 | -0.218 | -0.0430 | No |
| 133 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 12737 | -0.231 | -0.0401 | No |
| 134 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.0312 | No |
| 135 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | -0.0308 | No |
| 136 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 12901 | -0.267 | -0.0221 | No |
| 137 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 13083 | -0.319 | -0.0231 | No |
| 138 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13097 | -0.326 | -0.0111 | No |
| 139 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 13159 | -0.370 | -0.0010 | No |
| 140 | H1F0 | H1F0 Entrez, Source | H1 histone family, member 0 | 13165 | -0.372 | 0.0134 | No |
