Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetCHIARETTI_T_ALL_DIFF
Enrichment Score (ES)0.48702127
Normalized Enrichment Score (NES)1.8478369
Nominal p-value0.0
FDR q-value0.01895531
FWER p-Value0.78
Table: GSEA Results Summary



Fig 1: Enrichment plot: CHIARETTI_T_ALL_DIFF   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog31.6220.0602Yes
2IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 7111.2760.1071Yes
3CCND2CCND2
Entrez,  Source
cyclin D2211.0390.1451Yes
4ANXA1ANXA1
Entrez,  Source
annexin A1250.9950.1819Yes
5MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)310.9350.2163Yes
6RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa500.8100.2451Yes
7ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 2510.8090.2752Yes
8ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle600.7620.3030Yes
9RGS1RGS1
Entrez,  Source
regulator of G-protein signalling 1730.7150.3287Yes
10LGALS1LGALS1
Entrez,  Source
lectin, galactoside-binding, soluble, 1 (galectin 1)820.6870.3537Yes
11AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)1640.5410.3677Yes
12SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21900.4990.3844Yes
13CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 22180.4710.3999Yes
14TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32570.4320.4131Yes
15SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)3140.3880.4233Yes
16SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 13360.3710.4355Yes
17PF4PF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)3640.3570.4467Yes
18PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)3930.3400.4573Yes
19ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule5070.2820.4592Yes
20EMP3EMP3
Entrez,  Source
epithelial membrane protein 36620.2430.4566Yes
21S100A8S100A8
Entrez,  Source
S100 calcium binding protein A87250.2310.4605Yes
22PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 17640.2230.4659Yes
23LMO4LMO4
Entrez,  Source
LIM domain only 48240.2090.4692Yes
24FXYD2FXYD2
Entrez,  Source
FXYD domain containing ion transport regulator 29600.1870.4659Yes
25BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 310250.1790.4677Yes
26TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)10520.1770.4723Yes
27PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E10820.1730.4766Yes
28CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor12410.1570.4704Yes
29DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112660.1540.4743Yes
30S100A4S100A4
Entrez,  Source
S100 calcium binding protein A412850.1520.4786Yes
31ANXA5ANXA5
Entrez,  Source
annexin A513670.1460.4779Yes
32CTSHCTSH
Entrez,  Source
cathepsin H14010.1430.4807Yes
33PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha14230.1410.4844Yes
34CCL3CCL3
Entrez,  Source
chemokine (C-C motif) ligand 315080.1340.4830Yes
35ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 116270.1270.4788Yes
36HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)16890.1230.4788Yes
37RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 317230.1210.4808Yes
38ALOX5ALOX5
Entrez,  Source
arachidonate 5-lipoxygenase17360.1200.4843Yes
39MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 117600.1190.4870Yes
40PTTG1IPPTTG1IP
Entrez,  Source
pituitary tumor-transforming 1 interacting protein18290.1150.4862No
41ATF3ATF3
Entrez,  Source
activating transcription factor 320350.1060.4746No
42TRHTRH
Entrez,  Source
thyrotropin-releasing hormone21240.1030.4717No
43PDLIM1PDLIM1
Entrez,  Source
PDZ and LIM domain 1 (elfin)21490.1010.4737No
44BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)22980.0960.4660No
45DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 624900.0880.4548No
46ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 325610.0850.4527No
47BCL11ABCL11A
Entrez,  Source
B-cell CLL/lymphoma 11A (zinc finger protein)25840.0840.4541No
48RCBTB2RCBTB2
Entrez,  Source
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 227100.0800.4476No
49GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 328160.0770.4425No
50CD2CD2
Entrez,  Source
CD2 molecule28520.0760.4427No
51PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)28940.0740.4423No
52TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor29640.0720.4398No
53FRMD4BFRMD4B
Entrez,  Source
FERM domain containing 4B30480.0700.4361No
54ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)31030.0680.4345No
55CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)32020.0660.4296No
56LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)32380.0640.4293No
57SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 232800.0630.4286No
58NOTCH3NOTCH3
Entrez,  Source
Notch homolog 3 (Drosophila)32810.0630.4309No
59ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein32860.0630.4330No
60IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 134720.0580.4211No
61ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein34790.0580.4228No
62TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)35060.0570.4230No
63ALDH1A2ALDH1A2
Entrez,  Source
aldehyde dehydrogenase 1 family, member A237100.0520.4095No
64SPON1SPON1
Entrez,  Source
spondin 1, extracellular matrix protein37260.0520.4103No
65PRSS1PRSS1
Entrez,  Source
protease, serine, 1 (trypsin 1)37780.0510.4083No
66MALMAL
Entrez,  Source
mal, T-cell differentiation protein38220.0500.4069No
67NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)40250.0440.3932No
68PRDX2PRDX2
Entrez,  Source
peroxiredoxin 240630.0430.3920No
69HES1HES1
Entrez,  Source
hairy and enhancer of split 1, (Drosophila)42480.0380.3795No
70GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 242770.0380.3788No
71IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3044540.0350.3668No
72ST18ST18
Entrez,  Source
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)44970.0340.3648No
73S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1046300.0310.3560No
74SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)47960.0280.3445No
75CD8ACD8A
Entrez,  Source
CD8a molecule50150.0240.3289No
76EPHB6EPHB6
Entrez,  Source
EPH receptor B651520.0210.3194No
77IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)51880.0200.3175No
78PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule52640.0190.3125No
79UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase53840.0170.3041No
80SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase56500.0120.2845No
81FHL1FHL1
Entrez,  Source
four and a half LIM domains 156600.0120.2843No
82SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like58800.0080.2679No
83PPBPPPBP
Entrez,  Source
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)59090.0070.2661No
84CD97CD97
Entrez,  Source
CD97 molecule59950.0050.2598No
85CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 259970.0050.2599No
86CD52CD52
Entrez,  Source
CD52 molecule60240.0050.2581No
87CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta60620.0040.2555No
88ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 166337-0.0010.2347No
89SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)6379-0.0010.2317No
90CCL5CCL5
Entrez,  Source
chemokine (C-C motif) ligand 56393-0.0020.2308No
91CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)6502-0.0040.2227No
92LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)6756-0.0080.2038No
93TOB1TOB1
Entrez,  Source
transducer of ERBB2, 16785-0.0090.2020No
94WASF1WASF1
Entrez,  Source
WAS protein family, member 16866-0.0100.1963No
95CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase6929-0.0110.1920No
96MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)6942-0.0110.1916No
97ITGA6ITGA6
Entrez,  Source
integrin, alpha 67051-0.0130.1839No
98CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A7186-0.0160.1743No
99SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 37341-0.0190.1633No
100FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)7859-0.0280.1252No
101IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)8056-0.0320.1115No
102MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase8458-0.0410.0826No
103ADFPADFP
Entrez,  Source
adipose differentiation-related protein8468-0.0410.0835No
104S100A9S100A9
Entrez,  Source
S100 calcium binding protein A98582-0.0430.0765No
105ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 68733-0.0460.0669No
106CATCAT
Entrez,  Source
catalase8873-0.0490.0582No
107CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)8893-0.0500.0586No
108AHRAHR
Entrez,  Source
aryl hydrocarbon receptor9118-0.0540.0436No
109IL4RIL4R
Entrez,  Source
interleukin 4 receptor9312-0.0580.0312No
110SELLSELL
Entrez,  Source
selectin L (lymphocyte adhesion molecule 1)9375-0.0600.0287No
111CD200CD200
Entrez,  Source
CD200 molecule9392-0.0600.0297No
112AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)9501-0.0630.0239No
113RAP2BRAP2B
Entrez,  Source
RAP2B, member of RAS oncogene family9555-0.0640.0223No
114HIST1H2BLHIST1H2BL
Entrez,  Source
histone cluster 1, H2bl9625-0.0660.0195No
115PSPHPSPH
Entrez,  Source
phosphoserine phosphatase9762-0.0690.0118No
116STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)9987-0.076-0.0024No
117DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 29991-0.0760.0002No
118GARNL1GARNL1
Entrez,  Source
GTPase activating Rap/RanGAP domain-like 110148-0.080-0.0086No
119LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog10258-0.083-0.0138No
120RASGRP1RASGRP1
Entrez,  Source
RAS guanyl releasing protein 1 (calcium and DAG-regulated)10260-0.083-0.0107No
121LATLAT
Entrez,  Source
linker for activation of T cells10563-0.092-0.0302No
122NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated10654-0.095-0.0335No
123LAPTM4BLAPTM4B
Entrez,  Source
lysosomal associated protein transmembrane 4 beta10724-0.098-0.0351No
124HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed10765-0.099-0.0344No
125STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa11180-0.115-0.0615No
126PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 211205-0.116-0.0590No
127CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)11461-0.127-0.0735No
128IGJIGJ
Entrez,  Source
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides11506-0.129-0.0721No
129ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa11943-0.153-0.0994No
130HOXA5HOXA5
Entrez,  Source
homeobox A511961-0.154-0.0950No
131CSDACSDA
Entrez,  Source
cold shock domain protein A12139-0.167-0.1022No
132DDIT4DDIT4
Entrez,  Source
DNA-damage-inducible transcript 412217-0.173-0.1016No
133MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)12249-0.175-0.0974No
134GCH1GCH1
Entrez,  Source
GTP cyclohydrolase 1 (dopa-responsive dystonia)12298-0.179-0.0944No
135ARID5AARID5A
Entrez,  Source
AT rich interactive domain 5A (MRF1-like)12420-0.190-0.0965No
136SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 212493-0.198-0.0946No
137CD69CD69
Entrez,  Source
CD69 molecule12507-0.200-0.0881No
138USP1USP1
Entrez,  Source
ubiquitin specific peptidase 112629-0.215-0.0893No
139TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)12632-0.215-0.0814No
140ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like12653-0.218-0.0748No
141QKIQKI
Entrez,  Source
quaking homolog, KH domain RNA binding (mouse)12737-0.231-0.0725No
142HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like12742-0.232-0.0642No
143BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 212874-0.260-0.0645No
144SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)12901-0.267-0.0565No
145KLF10KLF10
Entrez,  Source
Kruppel-like factor 1013083-0.319-0.0583No
146G0S2G0S2
Entrez,  Source
G0/G1switch 213097-0.326-0.0472No
147IRF7IRF7
Entrez,  Source
interferon regulatory factor 713119-0.337-0.0362No
148CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 413159-0.370-0.0254No
149H1F0H1F0
Entrez,  Source
H1 histone family, member 013165-0.372-0.0119No
150IFI44IFI44
Entrez,  Source
interferon-induced protein 4413315-0.6790.0020No
Table: GSEA details [plain text format]



Fig 2: CHIARETTI_T_ALL_DIFF   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CHIARETTI_T_ALL_DIFF: Random ES distribution   
Gene set null distribution of ES for CHIARETTI_T_ALL_DIFF