Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | CHROMOSOMAL_PART |
| Enrichment Score (ES) | -0.4348609 |
| Normalized Enrichment Score (NES) | -1.4618062 |
| Nominal p-value | 0.04121475 |
| FDR q-value | 0.249178 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 31 | 0.935 | 0.1685 | No |
| 2 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2162 | 0.101 | 0.0268 | No |
| 3 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 2298 | 0.096 | 0.0340 | No |
| 4 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2752 | 0.078 | 0.0143 | No |
| 5 | REPIN1 | REPIN1 Entrez, Source | replication initiator 1 | 4032 | 0.044 | -0.0739 | No |
| 6 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.0815 | No |
| 7 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 4548 | 0.033 | -0.0994 | No |
| 8 | SC65 | SC65 Entrez, Source | - | 4719 | 0.030 | -0.1067 | No |
| 9 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 4726 | 0.030 | -0.1017 | No |
| 10 | JUND | JUND Entrez, Source | jun D proto-oncogene | 5289 | 0.019 | -0.1405 | No |
| 11 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 5848 | 0.008 | -0.1810 | No |
| 12 | NPM2 | NPM2 Entrez, Source | nucleophosmin/nucleoplasmin, 2 | 6472 | -0.003 | -0.2273 | No |
| 13 | APC | APC Entrez, Source | adenomatosis polyposis coli | 7641 | -0.024 | -0.3107 | No |
| 14 | TNP1 | TNP1 Entrez, Source | transition protein 1 (during histone to protamine replacement) | 8326 | -0.038 | -0.3552 | No |
| 15 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 8446 | -0.040 | -0.3568 | No |
| 16 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 8660 | -0.045 | -0.3647 | No |
| 17 | H2AFY | H2AFY Entrez, Source | H2A histone family, member Y | 8887 | -0.050 | -0.3726 | No |
| 18 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 8962 | -0.051 | -0.3689 | No |
| 19 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 9220 | -0.056 | -0.3779 | No |
| 20 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9428 | -0.061 | -0.3823 | No |
| 21 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9713 | -0.068 | -0.3911 | No |
| 22 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 9714 | -0.068 | -0.3786 | No |
| 23 | HMGN1 | HMGN1 Entrez, Source | high-mobility group nucleosome binding domain 1 | 10136 | -0.080 | -0.3957 | No |
| 24 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 10658 | -0.096 | -0.4174 | Yes |
| 25 | SUGT1 | SUGT1 Entrez, Source | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 10813 | -0.101 | -0.4105 | Yes |
| 26 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 10944 | -0.106 | -0.4008 | Yes |
| 27 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 10956 | -0.107 | -0.3821 | Yes |
| 28 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 10986 | -0.108 | -0.3647 | Yes |
| 29 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 11423 | -0.126 | -0.3744 | Yes |
| 30 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.3531 | Yes |
| 31 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 11547 | -0.131 | -0.3365 | Yes |
| 32 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 11576 | -0.132 | -0.3144 | Yes |
| 33 | ZWINT | ZWINT Entrez, Source | ZW10 interactor | 11637 | -0.135 | -0.2942 | Yes |
| 34 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 11805 | -0.145 | -0.2803 | Yes |
| 35 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11931 | -0.152 | -0.2620 | Yes |
| 36 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11965 | -0.155 | -0.2362 | Yes |
| 37 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.2104 | Yes |
| 38 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12263 | -0.177 | -0.1974 | Yes |
| 39 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.1898 | Yes |
| 40 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 12855 | -0.255 | -0.1539 | Yes |
| 41 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12933 | -0.273 | -0.1098 | Yes |
| 42 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.0626 | Yes |
| 43 | APTX | APTX Entrez, Source | aprataxin | 13232 | -0.441 | 0.0083 | Yes |
