Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | COCAINE_BRAIN_5D_UP |
| Enrichment Score (ES) | 0.58270967 |
| Normalized Enrichment Score (NES) | 1.7890183 |
| Nominal p-value | 0.005504587 |
| FDR q-value | 0.030829921 |
| FWER p-Value | 0.964 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.1832 | Yes |
| 2 | TMEM50B | TMEM50B Entrez, Source | transmembrane protein 50B | 79 | 0.689 | 0.3245 | Yes |
| 3 | PVRL2 | PVRL2 Entrez, Source | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 126 | 0.616 | 0.4501 | Yes |
| 4 | ITFG1 | ITFG1 Entrez, Source | integrin alpha FG-GAP repeat containing 1 | 485 | 0.291 | 0.4842 | Yes |
| 5 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 768 | 0.222 | 0.5094 | Yes |
| 6 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 862 | 0.201 | 0.5446 | Yes |
| 7 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 901 | 0.195 | 0.5827 | Yes |
| 8 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 1501 | 0.135 | 0.5659 | No |
| 9 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 1801 | 0.117 | 0.5679 | No |
| 10 | NPTN | NPTN Entrez, Source | neuroplastin | 3133 | 0.068 | 0.4820 | No |
| 11 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3311 | 0.062 | 0.4818 | No |
| 12 | ATP1B2 | ATP1B2 Entrez, Source | ATPase, Na+/K+ transporting, beta 2 polypeptide | 3398 | 0.060 | 0.4880 | No |
| 13 | SH3GL3 | SH3GL3 Entrez, Source | SH3-domain GRB2-like 3 | 4015 | 0.044 | 0.4509 | No |
| 14 | PTP4A2 | PTP4A2 Entrez, Source | protein tyrosine phosphatase type IVA, member 2 | 4260 | 0.038 | 0.4406 | No |
| 15 | CAMK2A | CAMK2A Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha | 4303 | 0.037 | 0.4453 | No |
| 16 | BTRC | BTRC Entrez, Source | beta-transducin repeat containing | 4316 | 0.037 | 0.4522 | No |
| 17 | MARK2 | MARK2 Entrez, Source | MAP/microtubule affinity-regulating kinase 2 | 4871 | 0.027 | 0.4162 | No |
| 18 | MAPRE3 | MAPRE3 Entrez, Source | microtubule-associated protein, RP/EB family, member 3 | 5737 | 0.010 | 0.3533 | No |
| 19 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 6082 | 0.004 | 0.3282 | No |
| 20 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 6096 | 0.003 | 0.3279 | No |
| 21 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | 0.3039 | No |
| 22 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 6480 | -0.003 | 0.3003 | No |
| 23 | LENG8 | LENG8 Entrez, Source | leukocyte receptor cluster (LRC) member 8 | 6487 | -0.003 | 0.3005 | No |
| 24 | SYP | SYP Entrez, Source | synaptophysin | 6623 | -0.006 | 0.2916 | No |
| 25 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 7164 | -0.015 | 0.2542 | No |
| 26 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 7179 | -0.015 | 0.2563 | No |
| 27 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 7315 | -0.018 | 0.2500 | No |
| 28 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 7584 | -0.023 | 0.2347 | No |
| 29 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 7759 | -0.027 | 0.2272 | No |
| 30 | NRGN | NRGN Entrez, Source | neurogranin (protein kinase C substrate, RC3) | 7888 | -0.029 | 0.2236 | No |
| 31 | PALM | PALM Entrez, Source | paralemmin | 7979 | -0.031 | 0.2233 | No |
| 32 | GRIA1 | GRIA1 Entrez, Source | glutamate receptor, ionotropic, AMPA 1 | 8221 | -0.036 | 0.2127 | No |
| 33 | CD47 | CD47 Entrez, Source | CD47 molecule | 8623 | -0.044 | 0.1918 | No |
| 34 | MTMR9 | MTMR9 Entrez, Source | myotubularin related protein 9 | 8956 | -0.051 | 0.1774 | No |
| 35 | ZFP64 | ZFP64 Entrez, Source | zinc finger protein 64 homolog (mouse) | 9098 | -0.054 | 0.1781 | No |
| 36 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.1773 | No |
| 37 | UNC93B1 | UNC93B1 Entrez, Source | unc-93 homolog B1 (C. elegans) | 9658 | -0.067 | 0.1622 | No |
| 38 | JUP | JUP Entrez, Source | junction plakoglobin | 9963 | -0.075 | 0.1552 | No |
| 39 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 10051 | -0.078 | 0.1650 | No |
| 40 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 10684 | -0.097 | 0.1377 | No |
| 41 | PTPN5 | PTPN5 Entrez, Source | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 11514 | -0.130 | 0.1025 | No |
| 42 | WBP11 | WBP11 Entrez, Source | WW domain binding protein 11 | 12119 | -0.166 | 0.0919 | No |
