Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CORDERO_KRAS_KD_VS_CONTROL_UP |
| Enrichment Score (ES) | 0.6524845 |
| Normalized Enrichment Score (NES) | 2.0188584 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004271501 |
| FWER p-Value | 0.109 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 11 | 1.276 | 0.1252 | Yes |
| 2 | TAGLN | TAGLN Entrez, Source | transgelin | 40 | 0.874 | 0.2094 | Yes |
| 3 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 89 | 0.680 | 0.2729 | Yes |
| 4 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 138 | 0.591 | 0.3277 | Yes |
| 5 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 190 | 0.499 | 0.3731 | Yes |
| 6 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 191 | 0.498 | 0.4222 | Yes |
| 7 | SLC22A5 | SLC22A5 Entrez, Source | solute carrier family 22 (organic cation transporter), member 5 | 311 | 0.392 | 0.4520 | Yes |
| 8 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 355 | 0.363 | 0.4846 | Yes |
| 9 | WASPIP | WASPIP Entrez, Source | Wiskott-Aldrich syndrome protein interacting protein | 358 | 0.359 | 0.5199 | Yes |
| 10 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 405 | 0.336 | 0.5496 | Yes |
| 11 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 480 | 0.292 | 0.5729 | Yes |
| 12 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 525 | 0.277 | 0.5970 | Yes |
| 13 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 533 | 0.274 | 0.6235 | Yes |
| 14 | ECE1 | ECE1 Entrez, Source | endothelin converting enzyme 1 | 814 | 0.211 | 0.6233 | Yes |
| 15 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.6348 | Yes |
| 16 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 932 | 0.190 | 0.6525 | Yes |
| 17 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 1302 | 0.150 | 0.6396 | No |
| 18 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 1445 | 0.139 | 0.6426 | No |
| 19 | GLIPR1 | GLIPR1 Entrez, Source | GLI pathogenesis-related 1 (glioma) | 2146 | 0.102 | 0.6000 | No |
| 20 | DKK3 | DKK3 Entrez, Source | dickkopf homolog 3 (Xenopus laevis) | 2164 | 0.101 | 0.6087 | No |
| 21 | CHST3 | CHST3 Entrez, Source | carbohydrate (chondroitin 6) sulfotransferase 3 | 2214 | 0.099 | 0.6148 | No |
| 22 | SNAI1 | SNAI1 Entrez, Source | snail homolog 1 (Drosophila) | 2341 | 0.094 | 0.6146 | No |
| 23 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2752 | 0.078 | 0.5915 | No |
| 24 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 3222 | 0.065 | 0.5627 | No |
| 25 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 3561 | 0.056 | 0.5428 | No |
| 26 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 4125 | 0.042 | 0.5045 | No |
| 27 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 4280 | 0.038 | 0.4967 | No |
| 28 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 5081 | 0.023 | 0.4388 | No |
| 29 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5789 | 0.009 | 0.3865 | No |
| 30 | WISP2 | WISP2 Entrez, Source | WNT1 inducible signaling pathway protein 2 | 6134 | 0.003 | 0.3609 | No |
| 31 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 6293 | -0.000 | 0.3491 | No |
| 32 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 6563 | -0.005 | 0.3293 | No |
| 33 | JUN | JUN Entrez, Source | jun oncogene | 6649 | -0.006 | 0.3235 | No |
| 34 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 8005 | -0.031 | 0.2247 | No |
| 35 | ADAM19 | ADAM19 Entrez, Source | ADAM metallopeptidase domain 19 (meltrin beta) | 8788 | -0.048 | 0.1706 | No |
| 36 | ATP2B4 | ATP2B4 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 4 | 9524 | -0.063 | 0.1216 | No |
| 37 | GPR56 | GPR56 Entrez, Source | G protein-coupled receptor 56 | 9622 | -0.066 | 0.1209 | No |
| 38 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 9767 | -0.070 | 0.1169 | No |
| 39 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 11158 | -0.115 | 0.0237 | No |
| 40 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 12873 | -0.260 | -0.0795 | No |
| 41 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | -0.0539 | No |
| 42 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12951 | -0.277 | -0.0322 | No |
| 43 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 12969 | -0.282 | -0.0057 | No |
| 44 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 13125 | -0.341 | 0.0163 | No |
