Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | 0.7758739 |
| Normalized Enrichment Score (NES) | 2.1389003 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.001016047 |
| FWER p-Value | 0.0090 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 3 | 1.622 | 0.1474 | Yes |
| 2 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 11 | 1.276 | 0.2630 | Yes |
| 3 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12 | 1.254 | 0.3772 | Yes |
| 4 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 13 | 1.195 | 0.4859 | Yes |
| 5 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.5649 | Yes |
| 6 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 50 | 0.810 | 0.6377 | Yes |
| 7 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.6681 | Yes |
| 8 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 342 | 0.369 | 0.6924 | Yes |
| 9 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 480 | 0.292 | 0.7087 | Yes |
| 10 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 533 | 0.274 | 0.7297 | Yes |
| 11 | LOX | LOX Entrez, Source | lysyl oxidase | 558 | 0.267 | 0.7522 | Yes |
| 12 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 565 | 0.265 | 0.7759 | Yes |
| 13 | IER3 | IER3 Entrez, Source | immediate early response 3 | 908 | 0.195 | 0.7679 | No |
| 14 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.7551 | No |
| 15 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 1282 | 0.152 | 0.7679 | No |
| 16 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 1508 | 0.134 | 0.7632 | No |
| 17 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 1735 | 0.120 | 0.7572 | No |
| 18 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 3281 | 0.063 | 0.6469 | No |
| 19 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 4125 | 0.042 | 0.5874 | No |
| 20 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 4738 | 0.029 | 0.5441 | No |
| 21 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 4827 | 0.027 | 0.5400 | No |
| 22 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 5285 | 0.019 | 0.5074 | No |
| 23 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 7897 | -0.029 | 0.3140 | No |
| 24 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 10955 | -0.107 | 0.0941 | No |
| 25 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 11087 | -0.111 | 0.0944 | No |
| 26 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 12585 | -0.209 | 0.0010 | No |
| 27 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12951 | -0.277 | -0.0013 | No |
| 28 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 13117 | -0.336 | 0.0169 | No |
