Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | DNA_REPLICATION |
| Enrichment Score (ES) | -0.46824187 |
| Normalized Enrichment Score (NES) | -1.5468996 |
| Nominal p-value | 0.016241299 |
| FDR q-value | 0.21294689 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 562 | 0.267 | 0.0084 | No |
| 2 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 1377 | 0.144 | -0.0253 | No |
| 3 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 1815 | 0.116 | -0.0360 | No |
| 4 | EREG | EREG Entrez, Source | epiregulin | 1968 | 0.109 | -0.0267 | No |
| 5 | KCTD13 | KCTD13 Entrez, Source | potassium channel tetramerisation domain containing 13 | 2108 | 0.103 | -0.0175 | No |
| 6 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 2663 | 0.081 | -0.0437 | No |
| 7 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 2867 | 0.075 | -0.0447 | No |
| 8 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 3110 | 0.068 | -0.0499 | No |
| 9 | REPIN1 | REPIN1 Entrez, Source | replication initiator 1 | 4032 | 0.044 | -0.1109 | No |
| 10 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 4748 | 0.029 | -0.1591 | No |
| 11 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.1862 | No |
| 12 | PTMS | PTMS Entrez, Source | parathymosin | 5794 | 0.009 | -0.2319 | No |
| 13 | GLI1 | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 6239 | 0.001 | -0.2652 | No |
| 14 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6268 | 0.000 | -0.2672 | No |
| 15 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 6399 | -0.002 | -0.2767 | No |
| 16 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 6622 | -0.006 | -0.2923 | No |
| 17 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 7357 | -0.019 | -0.3439 | No |
| 18 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 7645 | -0.024 | -0.3608 | No |
| 19 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8016 | -0.032 | -0.3827 | No |
| 20 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 8169 | -0.035 | -0.3875 | No |
| 21 | NBN | NBN Entrez, Source | nibrin | 8672 | -0.045 | -0.4167 | No |
| 22 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 9134 | -0.055 | -0.4410 | No |
| 23 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9497 | -0.063 | -0.4563 | Yes |
| 24 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 9513 | -0.063 | -0.4454 | Yes |
| 25 | MUTYH | MUTYH Entrez, Source | mutY homolog (E. coli) | 9606 | -0.065 | -0.4399 | Yes |
| 26 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 9639 | -0.066 | -0.4297 | Yes |
| 27 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9713 | -0.068 | -0.4222 | Yes |
| 28 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 9897 | -0.074 | -0.4219 | Yes |
| 29 | IGHMBP2 | IGHMBP2 Entrez, Source | immunoglobulin mu binding protein 2 | 9982 | -0.076 | -0.4138 | Yes |
| 30 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.4312 | Yes |
| 31 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 10527 | -0.091 | -0.4205 | Yes |
| 32 | WRNIP1 | WRNIP1 Entrez, Source | Werner helicase interacting protein 1 | 10609 | -0.094 | -0.4088 | Yes |
| 33 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 10762 | -0.099 | -0.4013 | Yes |
| 34 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11183 | -0.116 | -0.4109 | Yes |
| 35 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11541 | -0.131 | -0.4129 | Yes |
| 36 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 11547 | -0.131 | -0.3883 | Yes |
| 37 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 11705 | -0.138 | -0.3738 | Yes |
| 38 | GTPBP4 | GTPBP4 Entrez, Source | GTP binding protein 4 | 11715 | -0.139 | -0.3480 | Yes |
| 39 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 11975 | -0.156 | -0.3379 | Yes |
| 40 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.3101 | Yes |
| 41 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12591 | -0.209 | -0.3142 | Yes |
| 42 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.2802 | Yes |
| 43 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12718 | -0.226 | -0.2375 | Yes |
| 44 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12830 | -0.249 | -0.1984 | Yes |
| 45 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12847 | -0.253 | -0.1515 | Yes |
| 46 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1070 | Yes |
| 47 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.0527 | Yes |
| 48 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13163 | -0.372 | 0.0135 | Yes |
