Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.6470754 |
| Normalized Enrichment Score (NES) | -1.875488 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.024562111 |
| FWER p-Value | 0.547 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 2867 | 0.075 | -0.1898 | No |
| 2 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 4748 | 0.029 | -0.3211 | No |
| 3 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 6034 | 0.005 | -0.4161 | No |
| 4 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 6089 | 0.003 | -0.4189 | No |
| 5 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 6399 | -0.002 | -0.4416 | No |
| 6 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 7357 | -0.019 | -0.5070 | No |
| 7 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 8169 | -0.035 | -0.5562 | No |
| 8 | UBB | UBB Entrez, Source | ubiquitin B | 8206 | -0.035 | -0.5469 | No |
| 9 | UBC | UBC Entrez, Source | ubiquitin C | 8543 | -0.042 | -0.5578 | No |
| 10 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9713 | -0.068 | -0.6224 | Yes |
| 11 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 10042 | -0.078 | -0.6208 | Yes |
| 12 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 10338 | -0.086 | -0.6139 | Yes |
| 13 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.5914 | Yes |
| 14 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 10527 | -0.091 | -0.5672 | Yes |
| 15 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10987 | -0.108 | -0.5652 | Yes |
| 16 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.5568 | Yes |
| 17 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11931 | -0.152 | -0.5415 | Yes |
| 18 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.4936 | Yes |
| 19 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12178 | -0.170 | -0.4489 | Yes |
| 20 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.4124 | Yes |
| 21 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12718 | -0.226 | -0.3361 | Yes |
| 22 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12830 | -0.249 | -0.2601 | Yes |
| 23 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.1694 | Yes |
| 24 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
