Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | DOUBLE_STRANDED_DNA_BINDING |
| Enrichment Score (ES) | -0.68984383 |
| Normalized Enrichment Score (NES) | -1.7969892 |
| Nominal p-value | 0.006122449 |
| FDR q-value | 0.047052246 |
| FWER p-Value | 0.889 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 1377 | 0.144 | -0.0498 | No |
| 2 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 3080 | 0.069 | -0.1521 | No |
| 3 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 5070 | 0.023 | -0.2929 | No |
| 4 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.2919 | No |
| 5 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 6213 | 0.001 | -0.3703 | No |
| 6 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 6550 | -0.005 | -0.3938 | No |
| 7 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 7645 | -0.024 | -0.4669 | No |
| 8 | SAFB | SAFB Entrez, Source | scaffold attachment factor B | 10617 | -0.094 | -0.6549 | Yes |
| 9 | MTERF | MTERF Entrez, Source | mitochondrial transcription termination factor | 10821 | -0.102 | -0.6325 | Yes |
| 10 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11266 | -0.119 | -0.6217 | Yes |
| 11 | HLF | HLF Entrez, Source | hepatic leukemia factor | 11411 | -0.125 | -0.5861 | Yes |
| 12 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 12139 | -0.167 | -0.5787 | Yes |
| 13 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 12212 | -0.172 | -0.5203 | Yes |
| 14 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.4741 | Yes |
| 15 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.3863 | Yes |
| 16 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 13036 | -0.304 | -0.2785 | Yes |
| 17 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13163 | -0.372 | -0.1502 | Yes |
| 18 | APTX | APTX Entrez, Source | aprataxin | 13232 | -0.441 | 0.0083 | Yes |
