Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ENZYME_ACTIVATOR_ACTIVITY |
| Enrichment Score (ES) | 0.5736832 |
| Normalized Enrichment Score (NES) | 1.9315821 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009359233 |
| FWER p-Value | 0.378 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 50 | 0.810 | 0.0767 | Yes |
| 2 | CD24 | CD24 Entrez, Source | CD24 molecule | 66 | 0.745 | 0.1496 | Yes |
| 3 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 73 | 0.715 | 0.2202 | Yes |
| 4 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 125 | 0.616 | 0.2776 | Yes |
| 5 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.3238 | Yes |
| 6 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 205 | 0.482 | 0.3703 | Yes |
| 7 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 301 | 0.402 | 0.4031 | Yes |
| 8 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 383 | 0.346 | 0.4314 | Yes |
| 9 | CDC42EP2 | CDC42EP2 Entrez, Source | CDC42 effector protein (Rho GTPase binding) 2 | 399 | 0.337 | 0.4638 | Yes |
| 10 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 474 | 0.294 | 0.4874 | Yes |
| 11 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 533 | 0.274 | 0.5103 | Yes |
| 12 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 639 | 0.247 | 0.5269 | Yes |
| 13 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 646 | 0.246 | 0.5509 | Yes |
| 14 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 740 | 0.229 | 0.5666 | Yes |
| 15 | MMP24 | MMP24 Entrez, Source | matrix metallopeptidase 24 (membrane-inserted) | 904 | 0.195 | 0.5737 | Yes |
| 16 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1486 | 0.136 | 0.5434 | No |
| 17 | RALBP1 | RALBP1 Entrez, Source | ralA binding protein 1 | 1617 | 0.127 | 0.5463 | No |
| 18 | GUCA2B | GUCA2B Entrez, Source | guanylate cyclase activator 2B (uroguanylin) | 2013 | 0.107 | 0.5271 | No |
| 19 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 2179 | 0.100 | 0.5247 | No |
| 20 | PSAP | PSAP Entrez, Source | prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) | 2220 | 0.099 | 0.5315 | No |
| 21 | IL2 | IL2 Entrez, Source | interleukin 2 | 2282 | 0.096 | 0.5364 | No |
| 22 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 2292 | 0.096 | 0.5453 | No |
| 23 | ARL1 | ARL1 Entrez, Source | ADP-ribosylation factor-like 1 | 2794 | 0.077 | 0.5152 | No |
| 24 | CENTA1 | CENTA1 Entrez, Source | centaurin, alpha 1 | 3167 | 0.067 | 0.4938 | No |
| 25 | RGS6 | RGS6 Entrez, Source | regulator of G-protein signalling 6 | 3368 | 0.061 | 0.4848 | No |
| 26 | ERRFI1 | ERRFI1 Entrez, Source | ERBB receptor feedback inhibitor 1 | 3633 | 0.054 | 0.4702 | No |
| 27 | BCL10 | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 3730 | 0.051 | 0.4681 | No |
| 28 | RCVRN | RCVRN Entrez, Source | recoverin | 3891 | 0.048 | 0.4608 | No |
| 29 | GMFG | GMFG Entrez, Source | glia maturation factor, gamma | 4398 | 0.036 | 0.4262 | No |
| 30 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 4478 | 0.034 | 0.4237 | No |
| 31 | ARHGAP4 | ARHGAP4 Entrez, Source | Rho GTPase activating protein 4 | 4793 | 0.028 | 0.4028 | No |
| 32 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 5002 | 0.024 | 0.3896 | No |
| 33 | RAP1GAP | RAP1GAP Entrez, Source | RAP1 GTPase activating protein | 5106 | 0.022 | 0.3840 | No |
| 34 | MAPK8IP2 | MAPK8IP2 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 2 | 5129 | 0.022 | 0.3845 | No |
| 35 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5840 | 0.008 | 0.3318 | No |
| 36 | RGS9 | RGS9 Entrez, Source | regulator of G-protein signalling 9 | 5873 | 0.008 | 0.3302 | No |
| 37 | ARHGAP27 | ARHGAP27 Entrez, Source | Rho GTPase activating protein 27 | 6001 | 0.005 | 0.3211 | No |
| 38 | CENTD2 | CENTD2 Entrez, Source | centaurin, delta 2 | 6123 | 0.003 | 0.3123 | No |
| 39 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 6645 | -0.006 | 0.2737 | No |
| 40 | RGS12 | RGS12 Entrez, Source | regulator of G-protein signalling 12 | 6660 | -0.007 | 0.2733 | No |
| 41 | F10 | F10 Entrez, Source | coagulation factor X | 7144 | -0.015 | 0.2383 | No |
| 42 | FGF13 | FGF13 Entrez, Source | fibroblast growth factor 13 | 7222 | -0.016 | 0.2342 | No |
| 43 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 7459 | -0.021 | 0.2185 | No |
| 44 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 7532 | -0.022 | 0.2152 | No |
| 45 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 7739 | -0.026 | 0.2023 | No |
| 46 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 8079 | -0.033 | 0.1800 | No |
| 47 | RGS14 | RGS14 Entrez, Source | regulator of G-protein signalling 14 | 8231 | -0.036 | 0.1722 | No |
| 48 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 8642 | -0.044 | 0.1458 | No |
| 49 | DBNL | DBNL Entrez, Source | drebrin-like | 8818 | -0.048 | 0.1373 | No |
| 50 | DNAJB6 | DNAJB6 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 6 | 9020 | -0.052 | 0.1274 | No |
| 51 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 9336 | -0.059 | 0.1095 | No |
| 52 | RASA2 | RASA2 Entrez, Source | RAS p21 protein activator 2 | 9408 | -0.061 | 0.1102 | No |
| 53 | RAB3GAP2 | RAB3GAP2 Entrez, Source | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 9593 | -0.065 | 0.1028 | No |
| 54 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9713 | -0.068 | 0.1007 | No |
| 55 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 9852 | -0.072 | 0.0975 | No |
| 56 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 10009 | -0.077 | 0.0933 | No |
| 57 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 10565 | -0.092 | 0.0607 | No |
| 58 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10704 | -0.097 | 0.0600 | No |
| 59 | TSC2 | TSC2 Entrez, Source | tuberous sclerosis 2 | 10848 | -0.103 | 0.0594 | No |
| 60 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 11004 | -0.108 | 0.0585 | No |
| 61 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 11129 | -0.113 | 0.0604 | No |
| 62 | APOA2 | APOA2 Entrez, Source | apolipoprotein A-II | 11263 | -0.119 | 0.0622 | No |
| 63 | RASA3 | RASA3 Entrez, Source | RAS p21 protein activator 3 | 11272 | -0.119 | 0.0734 | No |
| 64 | MYO9B | MYO9B Entrez, Source | myosin IXB | 11288 | -0.120 | 0.0842 | No |
| 65 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11793 | -0.144 | 0.0605 | No |
| 66 | PLAA | PLAA Entrez, Source | phospholipase A2-activating protein | 11873 | -0.149 | 0.0694 | No |
| 67 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 12278 | -0.177 | 0.0566 | No |
| 68 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 12770 | -0.237 | 0.0431 | No |
