Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetEXTRACELLULAR_REGION
Enrichment Score (ES)0.4316256
Normalized Enrichment Score (NES)1.7436665
Nominal p-value0.0
FDR q-value0.04146722
FWER p-Value0.997
Table: GSEA Results Summary



Fig 1: Enrichment plot: EXTRACELLULAR_REGION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NPYNPY
Entrez,  Source
neuropeptide Y41.5680.0411Yes
2COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 2121.2540.0737Yes
3CCL20CCL20
Entrez,  Source
chemokine (C-C motif) ligand 20270.9630.0981Yes
4CTGFCTGF
Entrez,  Source
connective tissue growth factor370.8880.1208Yes
5COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)430.8430.1427Yes
6COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2610.7590.1615Yes
7LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1030.6590.1757Yes
8LPLLPL
Entrez,  Source
lipoprotein lipase1070.6460.1926Yes
9MGPMGP
Entrez,  Source
matrix Gla protein1080.6440.2096Yes
10F13A1F13A1
Entrez,  Source
coagulation factor XIII, A1 polypeptide1860.5100.2172Yes
11CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 22180.4710.2272Yes
12PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein2290.4590.2386Yes
13GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)2420.4490.2495Yes
14FSTL1FSTL1
Entrez,  Source
follistatin-like 12460.4440.2610Yes
15GDF15GDF15
Entrez,  Source
growth differentiation factor 153150.3880.2661Yes
16RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma3230.3780.2755Yes
17SPINT1SPINT1
Entrez,  Source
serine peptidase inhibitor, Kunitz type 13480.3660.2833Yes
18CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 24050.3360.2879Yes
19PGCPPGCP
Entrez,  Source
-4060.3350.2968Yes
20CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)4170.3280.3047Yes
21CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)4740.2940.3082Yes
22LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)5300.2750.3112Yes
23LAMB2LAMB2
Entrez,  Source
laminin, beta 2 (laminin S)5900.2600.3136Yes
24IGFBP1IGFBP1
Entrez,  Source
insulin-like growth factor binding protein 15960.2580.3200Yes
25LBPLBP
Entrez,  Source
lipopolysaccharide binding protein6360.2470.3235Yes
26APOA1APOA1
Entrez,  Source
apolipoprotein A-I6460.2460.3293Yes
27EDN1EDN1
Entrez,  Source
endothelin 16480.2450.3357Yes
28GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)6660.2420.3408Yes
29AFMAFM
Entrez,  Source
afamin6810.2390.3461Yes
30C1QAC1QA
Entrez,  Source
complement component 1, q subcomponent, A chain6990.2360.3510Yes
31ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)7380.2290.3541Yes
32C1QBC1QB
Entrez,  Source
complement component 1, q subcomponent, B chain7860.2170.3563Yes
33WFDC2WFDC2
Entrez,  Source
WAP four-disulfide core domain 27940.2150.3614Yes
34CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 17960.2150.3670Yes
35APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)8340.2070.3696Yes
36FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)8350.2070.3751Yes
37EFEMP2EFEMP2
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 28520.2040.3793Yes
38SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 58760.1990.3828Yes
39TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 29160.1930.3849Yes
40USH2AUSH2A
Entrez,  Source
Usher syndrome 2A (autosomal recessive, mild)9180.1920.3899Yes
41CTF1CTF1
Entrez,  Source
cardiotrophin 19360.1900.3936Yes
42FBN1FBN1
Entrez,  Source
fibrillin 19680.1870.3961Yes
43KLKL
Entrez,  Source
klotho9710.1860.4009Yes
44ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 49880.1840.4045Yes
45COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 111030.1700.4003Yes
46APODAPOD
Entrez,  Source
apolipoprotein D11220.1690.4034Yes
47SCUBE1SCUBE1
Entrez,  Source
signal peptide, CUB domain, EGF-like 111620.1640.4047Yes
48FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 111780.1630.4079Yes
49IL6RIL6R
Entrez,  Source
interleukin 6 receptor12160.1600.4093Yes
50RNASE6RNASE6
Entrez,  Source
ribonuclease, RNase A family, k612320.1580.4123Yes
51KLK8KLK8
Entrez,  Source
kallikrein 8 (neuropsin/ovasin)12400.1570.4159Yes
52LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 112820.1520.4168Yes
53LTBP4LTBP4
Entrez,  Source
latent transforming growth factor beta binding protein 412960.1510.4198Yes
54PLA2G5PLA2G5
Entrez,  Source
phospholipase A2, group V12990.1510.4236Yes
55FGF12FGF12
Entrez,  Source
fibroblast growth factor 1213340.1480.4249Yes
56MMP7MMP7
Entrez,  Source
matrix metallopeptidase 7 (matrilysin, uterine)13850.1440.4249Yes
57APOA5APOA5
Entrez,  Source
apolipoprotein A-V14860.1360.4208Yes
58DMBT1DMBT1
Entrez,  Source
deleted in malignant brain tumors 114940.1350.4238Yes
59PCSK9PCSK9
Entrez,  Source
proprotein convertase subtilisin/kexin type 915140.1340.4259Yes
60ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)15220.1330.4289Yes
61NUCB1NUCB1
Entrez,  Source
nucleobindin 115890.1290.4272Yes
62TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia17290.1210.4198Yes
63CPB2CPB2
Entrez,  Source
carboxypeptidase B2 (plasma, carboxypeptidase U)17380.1200.4224Yes
64IMPG1IMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 117400.1200.4254Yes
65PROK2PROK2
Entrez,  Source
prokineticin 217570.1190.4274Yes
66VTNVTN
Entrez,  Source
vitronectin17760.1180.4291Yes
67SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)18450.1150.4269Yes
68AGGF1AGGF1
Entrez,  Source
angiogenic factor with G patch and FHA domains 118460.1150.4299Yes
69TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)19140.1110.4277Yes
70PRSS8PRSS8
Entrez,  Source
protease, serine, 8 (prostasin)19540.1100.4276Yes
71EREGEREG
Entrez,  Source
epiregulin19680.1090.4295Yes
72PRG2PRG2
Entrez,  Source
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)20440.1060.4266Yes
73TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)20760.1050.4270Yes
74DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein21630.1010.4230Yes
75DKK3DKK3
Entrez,  Source
dickkopf homolog 3 (Xenopus laevis)21640.1010.4257Yes
76PSAPPSAP
Entrez,  Source
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)22200.0990.4241Yes
77SGCESGCE
Entrez,  Source
sarcoglycan, epsilon22740.0960.4226Yes
78IL2IL2
Entrez,  Source
interleukin 222820.0960.4246Yes
79CSF3CSF3
Entrez,  Source
colony stimulating factor 3 (granulocyte)23060.0950.4253Yes
80SFRP1SFRP1
Entrez,  Source
secreted frizzled-related protein 123270.0940.4263Yes
81SGCGSGCG
Entrez,  Source
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)23350.0940.4282Yes
82PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)23530.0930.4294Yes
83SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 123610.0930.4313Yes
84VWFVWF
Entrez,  Source
von Willebrand factor24000.0920.4308Yes
85NUCB2NUCB2
Entrez,  Source
nucleobindin 224220.0910.4316Yes
86SEMA3ASEMA3A
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A24660.0890.4307No
87EGFL6EGFL6
Entrez,  Source
EGF-like-domain, multiple 625030.0880.4302No
88APOEAPOE
Entrez,  Source
apolipoprotein E26190.0830.4236No
89COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase26700.0810.4219No
90ECM1ECM1
Entrez,  Source
extracellular matrix protein 127180.0800.4204No
91FGF10FGF10
Entrez,  Source
fibroblast growth factor 1027650.0780.4190No
92MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)27750.0780.4203No
93LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase28880.0750.4137No
94PCSK2PCSK2
Entrez,  Source
proprotein convertase subtilisin/kexin type 229720.0720.4093No
95COL11A1COL11A1
Entrez,  Source
collagen, type XI, alpha 129810.0720.4105No
96MEP1BMEP1B
Entrez,  Source
meprin A, beta30440.0700.4076No
97SPINT2SPINT2
Entrez,  Source
serine peptidase inhibitor, Kunitz type, 230640.0690.4080No
98FGL2FGL2
Entrez,  Source
fibrinogen-like 231280.0680.4050No
99FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)32100.0650.4005No
100COL5A1COL5A1
Entrez,  Source
collagen, type V, alpha 132220.0650.4014No
101COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 433200.0620.3956No
102LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 233240.0620.3970No
103LAMA3LAMA3
Entrez,  Source
laminin, alpha 333440.0610.3972No
104EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 133780.0610.3962No
105MMP11MMP11
Entrez,  Source
matrix metallopeptidase 11 (stromelysin 3)34450.0590.3927No
106CRISP2CRISP2
Entrez,  Source
cysteine-rich secretory protein 234460.0590.3943No
107IL5RAIL5RA
Entrez,  Source
interleukin 5 receptor, alpha34480.0590.3958No
108CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)34490.0590.3974No
109GPHA2GPHA2
Entrez,  Source
glycoprotein hormone alpha 234750.0580.3970No
110PRSS2PRSS2
Entrez,  Source
protease, serine, 2 (trypsin 2)34800.0580.3982No
111IL18IL18
Entrez,  Source
interleukin 18 (interferon-gamma-inducing factor)35030.0570.3980No
112FGF20FGF20
Entrez,  Source
fibroblast growth factor 2035300.0570.3975No
113F2F2
Entrez,  Source
coagulation factor II (thrombin)35520.0560.3974No
114EPOEPO
Entrez,  Source
erythropoietin35770.0550.3970No
115TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 235910.0550.3975No
116MATN1MATN1
Entrez,  Source
matrilin 1, cartilage matrix protein36170.0540.3970No
117PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)36180.0540.3985No
118CRISP1CRISP1
Entrez,  Source
cysteine-rich secretory protein 137060.0520.3932No
119GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)37490.0510.3913No
120CARTPTCARTPT
Entrez,  Source
CART prepropeptide37690.0510.3912No
121TINAGTINAG
Entrez,  Source
tubulointerstitial nephritis antigen37700.0510.3925No
122NPPBNPPB
Entrez,  Source
natriuretic peptide precursor B38650.0480.3866No
123GPC1GPC1
Entrez,  Source
glypican 139280.0460.3831No
124FGF21FGF21
Entrez,  Source
fibroblast growth factor 2139410.0460.3834No
125NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)40250.0440.3782No
126KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)40600.0430.3767No
127FBLN2FBLN2
Entrez,  Source
fibulin 241170.0420.3735No
128TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa41250.0420.3741No
129CFHCFH
Entrez,  Source
complement factor H42090.0390.3688No
130SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)43300.0370.3605No
131CCL7CCL7
Entrez,  Source
chemokine (C-C motif) ligand 744090.0360.3555No
132LIPELIPE
Entrez,  Source
lipase, hormone-sensitive44100.0360.3564No
133IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3044540.0350.3541No
134TFF3TFF3
Entrez,  Source
trefoil factor 3 (intestinal)45940.0320.3443No
135PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone45950.0320.3451No
136INSL3INSL3
Entrez,  Source
insulin-like 3 (Leydig cell)47310.0300.3356No
137MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)49380.0250.3204No
138CAV3CAV3
Entrez,  Source
caveolin 349950.0240.3168No
139MEP1AMEP1A
Entrez,  Source
meprin A, alpha (PABA peptide hydrolase)50440.0230.3137No
140KLK10KLK10
Entrez,  Source
kallikrein 1050780.0230.3118No
141CPCP
Entrez,  Source
ceruloplasmin (ferroxidase)50930.0220.3113No
142IL13RA2IL13RA2
Entrez,  Source
interleukin 13 receptor, alpha 251460.0210.3079No
143FXYD6FXYD6
Entrez,  Source
FXYD domain containing ion transport regulator 651590.0210.3075No
144IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)51880.0200.3059No
145IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)52850.0190.2991No
146CCL28CCL28
Entrez,  Source
chemokine (C-C motif) ligand 2852900.0190.2993No
147FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)53810.0170.2928No
148COL16A1COL16A1
Entrez,  Source
collagen, type XVI, alpha 153880.0170.2928No
149WNT2BWNT2B
Entrez,  Source
wingless-type MMTV integration site family, member 2B54110.0160.2916No
150LGALS3BPLGALS3BP
Entrez,  Source
lectin, galactoside-binding, soluble, 3 binding protein55250.0140.2833No
151MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)55400.0140.2826No
152DMP1DMP1
Entrez,  Source
dentin matrix acidic phosphoprotein55450.0140.2826No
153ORM1ORM1
Entrez,  Source
orosomucoid 156060.0130.2784No
154PLA2G10PLA2G10
Entrez,  Source
phospholipase A2, group X56090.0130.2785No
155UTS2UTS2
Entrez,  Source
urotensin 256250.0120.2777No
156SLIT3SLIT3
Entrez,  Source
slit homolog 3 (Drosophila)57340.0100.2697No
157SCGB1D2SCGB1D2
Entrez,  Source
secretoglobin, family 1D, member 258300.0080.2627No
158MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response58770.0080.2593No
159PGCPGC
Entrez,  Source
progastricsin (pepsinogen C)58970.0070.2581No
160PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)59000.0070.2581No
161SFRP4SFRP4
Entrez,  Source
secreted frizzled-related protein 459200.0070.2568No
162SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 160630.0040.2460No
163IL5IL5
Entrez,  Source
interleukin 5 (colony-stimulating factor, eosinophil)60760.0040.2452No
164COL9A1COL9A1
Entrez,  Source
collagen, type IX, alpha 161310.0030.2412No
165EGFL7EGFL7
Entrez,  Source
EGF-like-domain, multiple 761960.0010.2363No
166FGF18FGF18
Entrez,  Source
fibroblast growth factor 1862460.0010.2326No
167MUC5ACMUC5AC
Entrez,  Source
mucin 5AC, oligomeric mucus/gel-forming62480.0010.2325No
168SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)6379-0.0010.2226No
169DLK1DLK1
Entrez,  Source
delta-like 1 homolog (Drosophila)6389-0.0020.2219No
170LGALS7LGALS7
Entrez,  Source
lectin, galactoside-binding, soluble, 7 (galectin 7)6454-0.0030.2171No
171MMP8MMP8
Entrez,  Source
matrix metallopeptidase 8 (neutrophil collagenase)6500-0.0040.2137No
172IL3IL3
Entrez,  Source
interleukin 3 (colony-stimulating factor, multiple)6521-0.0040.2123No
173CPN1CPN1
Entrez,  Source
carboxypeptidase N, polypeptide 1, 50kD6525-0.0040.2122No
174NOGNOG
Entrez,  Source
noggin6567-0.0050.2092No
175ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 26574-0.0050.2089No
176PLUNCPLUNC
Entrez,  Source
palate, lung and nasal epithelium carcinoma associated6625-0.0060.2052No
177PNLIPRP1PNLIPRP1
Entrez,  Source
pancreatic lipase-related protein 16658-0.0070.2029No
178FMODFMOD
Entrez,  Source
fibromodulin6665-0.0070.2026No
179TAC1TAC1
Entrez,  Source
tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)6693-0.0070.2007No
180IL9RIL9R
Entrez,  Source
interleukin 9 receptor6807-0.0090.1923No
181COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 16979-0.0120.1795No
182SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7093-0.0140.1712No
183CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha7138-0.0140.1683No
184CCL22CCL22
Entrez,  Source
chemokine (C-C motif) ligand 227142-0.0150.1684No
185CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A7186-0.0160.1655No
186FGF3FGF3
Entrez,  Source
fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)7225-0.0160.1631No
187SSTSST
Entrez,  Source
somatostatin7317-0.0180.1566No
188RNPEPRNPEP
Entrez,  Source
arginyl aminopeptidase (aminopeptidase B)7513-0.0220.1422No
189SCRG1SCRG1
Entrez,  Source
-7515-0.0220.1427No
190SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D7540-0.0220.1415No
191THBS4THBS4
Entrez,  Source
thrombospondin 47541-0.0220.1420No
192GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor7663-0.0250.1334No
193EFNA5EFNA5
Entrez,  Source
ephrin-A57672-0.0250.1335No
194CHADCHAD
Entrez,  Source
chondroadherin7677-0.0250.1338No
195PCSK1NPCSK1N
Entrez,  Source
proprotein convertase subtilisin/kexin type 1 inhibitor7755-0.0260.1286No
196INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)7768-0.0270.1284No
197TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 17942-0.0300.1160No
198PNOCPNOC
Entrez,  Source
prepronociceptin7957-0.0300.1157No
199SECTM1SECTM1
Entrez,  Source
secreted and transmembrane 17983-0.0310.1146No
200SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)8114-0.0340.1055No
201DNASE1DNASE1
Entrez,  Source
deoxyribonuclease I8122-0.0340.1059No
202LEPLEP
Entrez,  Source
leptin (obesity homolog, mouse)8124-0.0340.1067No
203IL12BIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)8161-0.0350.1048No
204HPXHPX
Entrez,  Source
hemopexin8287-0.0370.0963No
205INHAINHA
Entrez,  Source
inhibin, alpha8428-0.0400.0866No
206FGF6FGF6
Entrez,  Source
fibroblast growth factor 68436-0.0400.0871No
207ADFPADFP
Entrez,  Source
adipose differentiation-related protein8468-0.0410.0858No
208FBLN5FBLN5
Entrez,  Source
fibulin 58504-0.0420.0842No
209TMPRSS11DTMPRSS11D
Entrez,  Source
transmembrane protease, serine 11D8621-0.0440.0765No
210WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A8849-0.0490.0604No
211ATRNATRN
Entrez,  Source
attractin8885-0.0500.0590No
212HAPLN1HAPLN1
Entrez,  Source
hyaluronan and proteoglycan link protein 18916-0.0500.0580No
213LUMLUM
Entrez,  Source
lumican8919-0.0500.0592No
214PNLIPRP2PNLIPRP2
Entrez,  Source
pancreatic lipase-related protein 28921-0.0500.0605No
215ANGPT2ANGPT2
Entrez,  Source
angiopoietin 28929-0.0500.0613No
216AMY2AAMY2A
Entrez,  Source
amylase, alpha 2A; pancreatic9012-0.0520.0564No
217PTNPTN
Entrez,  Source
pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)9055-0.0530.0545No
218IMPG2IMPG2
Entrez,  Source
interphotoreceptor matrix proteoglycan 29065-0.0530.0553No
219REG3AREG3A
Entrez,  Source
regenerating islet-derived 3 alpha9086-0.0540.0551No
220FGF5FGF5
Entrez,  Source
fibroblast growth factor 59095-0.0540.0560No
221PLGPLG
Entrez,  Source
plasminogen9113-0.0540.0561No
222SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)9144-0.0550.0552No
223COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein9154-0.0550.0560No
224ACE2ACE2
Entrez,  Source
angiotensin I converting enzyme (peptidyl-dipeptidase A) 29170-0.0550.0563No
225IL7IL7
Entrez,  Source
interleukin 79178-0.0550.0572No
226FGF4FGF4
Entrez,  Source
fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)9186-0.0560.0582No
227CTRLCTRL
Entrez,  Source
chymotrypsin-like9254-0.0570.0545No
228MMP3MMP3
Entrez,  Source
matrix metallopeptidase 3 (stromelysin 1, progelatinase)9259-0.0570.0557No
229PDZD2PDZD2
Entrez,  Source
PDZ domain containing 29485-0.0630.0402No
230UTP11LUTP11L
Entrez,  Source
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)9535-0.0640.0381No
231IL15IL15
Entrez,  Source
interleukin 159600-0.0650.0349No
232IL18BPIL18BP
Entrez,  Source
interleukin 18 binding protein9609-0.0650.0360No
233FSTL3FSTL3
Entrez,  Source
follistatin-like 3 (secreted glycoprotein)9616-0.0660.0373No
234FRZBFRZB
Entrez,  Source
frizzled-related protein9647-0.0670.0368No
235AMHAMH
Entrez,  Source
anti-Mullerian hormone9648-0.0670.0385No
236FIGFFIGF
Entrez,  Source
c-fos induced growth factor (vascular endothelial growth factor D)9671-0.0670.0386No
237HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 19698-0.0680.0384No
238IL1BIL1B
Entrez,  Source
interleukin 1, beta9721-0.0690.0385No
239PLA2G2DPLA2G2D
Entrez,  Source
phospholipase A2, group IID9730-0.0690.0397No
240PVRPVR
Entrez,  Source
poliovirus receptor9752-0.0690.0400No
241FGGFGG
Entrez,  Source
fibrinogen gamma chain9841-0.0720.0351No
242GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone9852-0.0720.0363No
243PCSK5PCSK5
Entrez,  Source
proprotein convertase subtilisin/kexin type 59890-0.0730.0354No
244DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)9896-0.0740.0369No
245SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)9915-0.0740.0375No
246YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase9947-0.0750.0371No
247GRPGRP
Entrez,  Source
gastrin-releasing peptide10118-0.0790.0262No
248MSMBMSMB
Entrez,  Source
microseminoprotein, beta-10215-0.0820.0210No
249COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha10279-0.0840.0184No
250MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)10293-0.0840.0196No
251MFNGMFNG
Entrez,  Source
manic fringe homolog (Drosophila)10295-0.0840.0218No
252FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)10457-0.0890.0118No
253AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)10487-0.0900.0120No
254C2C2
Entrez,  Source
complement component 210542-0.0910.0102No
255SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310571-0.0920.0105No
256IDEIDE
Entrez,  Source
insulin-degrading enzyme10616-0.0940.0096No
257FGF17FGF17
Entrez,  Source
fibroblast growth factor 1710631-0.0950.0111No
258FGF16FGF16
Entrez,  Source
fibroblast growth factor 1610721-0.0980.0068No
259COL10A1COL10A1
Entrez,  Source
collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia)10885-0.104-0.0029No
260IKIK
Entrez,  Source
IK cytokine, down-regulator of HLA II10954-0.107-0.0053No
261RTN3RTN3
Entrez,  Source
reticulon 310973-0.107-0.0038No
262LGALS8LGALS8
Entrez,  Source
lectin, galactoside-binding, soluble, 8 (galectin 8)11061-0.110-0.0076No
263ADMADM
Entrez,  Source
adrenomedullin11063-0.110-0.0047No
264CCL4CCL4
Entrez,  Source
chemokine (C-C motif) ligand 411087-0.111-0.0036No
265HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor11219-0.117-0.0105No
266TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)11249-0.118-0.0096No
267APOA2APOA2
Entrez,  Source
apolipoprotein A-II11263-0.119-0.0075No
268LALBALALBA
Entrez,  Source
lactalbumin, alpha-11296-0.120-0.0067No
269CKLFCKLF
Entrez,  Source
chemokine-like factor11326-0.121-0.0058No
270COL5A3COL5A3
Entrez,  Source
collagen, type V, alpha 311366-0.123-0.0055No
271CFHR1CFHR1
Entrez,  Source
complement factor H-related 111475-0.128-0.0104No
272FGAFGA
Entrez,  Source
fibrinogen alpha chain11480-0.128-0.0073No
273APCSAPCS
Entrez,  Source
amyloid P component, serum11626-0.135-0.0149No
274IL4IL4
Entrez,  Source
interleukin 411640-0.135-0.0123No
275INHBCINHBC
Entrez,  Source
inhibin, beta C11706-0.138-0.0136No
276IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist11709-0.139-0.0101No
277FGL1FGL1
Entrez,  Source
fibrinogen-like 111898-0.150-0.0205No
278HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)11910-0.150-0.0174No
279MBL2MBL2
Entrez,  Source
mannose-binding lectin (protein C) 2, soluble (opsonic defect)11957-0.154-0.0169No
280CPA1CPA1
Entrez,  Source
carboxypeptidase A1 (pancreatic)12056-0.161-0.0201No
281FGBFGB
Entrez,  Source
fibrinogen beta chain12236-0.175-0.0292No
282MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)12291-0.179-0.0286No
283IL1AIL1A
Entrez,  Source
interleukin 1, alpha12379-0.186-0.0304No
284SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)12401-0.188-0.0270No
285RNH1RNH1
Entrez,  Source
ribonuclease/angiogenin inhibitor 112694-0.224-0.0435No
286IGFALSIGFALS
Entrez,  Source
insulin-like growth factor binding protein, acid labile subunit13179-0.383-0.0705No
287A1BGA1BG
Entrez,  Source
alpha-1-B glycoprotein13196-0.396-0.0612No
288CD5LCD5L
Entrez,  Source
CD5 molecule-like13324-0.805-0.0497No
289SERPINA7SERPINA7
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 713325-0.823-0.0280No
290CXCL9CXCL9
Entrez,  Source
chemokine (C-X-C motif) ligand 913337-1.1050.0004No
Table: GSEA details [plain text format]



Fig 2: EXTRACELLULAR_REGION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: EXTRACELLULAR_REGION: Random ES distribution   
Gene set null distribution of ES for EXTRACELLULAR_REGION