Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | FATTY_ACID_METABOLISM |
| Enrichment Score (ES) | 0.57097167 |
| Normalized Enrichment Score (NES) | 1.8473554 |
| Nominal p-value | 0.0034722222 |
| FDR q-value | 0.018705312 |
| FWER p-Value | 0.783 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 75 | 0.697 | 0.0500 | Yes |
| 2 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 77 | 0.697 | 0.1055 | Yes |
| 3 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 84 | 0.686 | 0.1598 | Yes |
| 4 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 91 | 0.673 | 0.2131 | Yes |
| 5 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 97 | 0.667 | 0.2660 | Yes |
| 6 | LPL | LPL Entrez, Source | lipoprotein lipase | 107 | 0.646 | 0.3169 | Yes |
| 7 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.3518 | Yes |
| 8 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 302 | 0.399 | 0.3749 | Yes |
| 9 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 329 | 0.374 | 0.4028 | Yes |
| 10 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 346 | 0.367 | 0.4309 | Yes |
| 11 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 375 | 0.349 | 0.4566 | Yes |
| 12 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 419 | 0.326 | 0.4794 | Yes |
| 13 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.4935 | Yes |
| 14 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 624 | 0.251 | 0.5062 | Yes |
| 15 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 722 | 0.231 | 0.5173 | Yes |
| 16 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 886 | 0.197 | 0.5208 | Yes |
| 17 | SDS | SDS Entrez, Source | serine dehydratase | 1007 | 0.182 | 0.5263 | Yes |
| 18 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 1221 | 0.159 | 0.5229 | Yes |
| 19 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 1343 | 0.147 | 0.5256 | Yes |
| 20 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.5304 | Yes |
| 21 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 1446 | 0.139 | 0.5403 | Yes |
| 22 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1482 | 0.136 | 0.5485 | Yes |
| 23 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1544 | 0.132 | 0.5544 | Yes |
| 24 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1627 | 0.127 | 0.5584 | Yes |
| 25 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1715 | 0.122 | 0.5616 | Yes |
| 26 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 1720 | 0.122 | 0.5710 | Yes |
| 27 | FASN | FASN Entrez, Source | fatty acid synthase | 2099 | 0.104 | 0.5508 | No |
| 28 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 2116 | 0.103 | 0.5578 | No |
| 29 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2173 | 0.101 | 0.5616 | No |
| 30 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.5406 | No |
| 31 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2640 | 0.082 | 0.5400 | No |
| 32 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 2671 | 0.081 | 0.5443 | No |
| 33 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 2893 | 0.074 | 0.5336 | No |
| 34 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 2947 | 0.073 | 0.5354 | No |
| 35 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 3091 | 0.069 | 0.5301 | No |
| 36 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 3141 | 0.067 | 0.5318 | No |
| 37 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 3429 | 0.060 | 0.5149 | No |
| 38 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 3710 | 0.052 | 0.4980 | No |
| 39 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 3794 | 0.050 | 0.4957 | No |
| 40 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 4375 | 0.036 | 0.4550 | No |
| 41 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 4410 | 0.036 | 0.4553 | No |
| 42 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 4448 | 0.035 | 0.4553 | No |
| 43 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 4624 | 0.032 | 0.4446 | No |
| 44 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 5216 | 0.020 | 0.4017 | No |
| 45 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 5880 | 0.008 | 0.3524 | No |
| 46 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6589 | -0.005 | 0.2996 | No |
| 47 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 6898 | -0.010 | 0.2772 | No |
| 48 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 7978 | -0.031 | 0.1984 | No |
| 49 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 9007 | -0.052 | 0.1252 | No |
| 50 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 10884 | -0.104 | -0.0077 | No |
| 51 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 11617 | -0.134 | -0.0520 | No |
| 52 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 11911 | -0.151 | -0.0621 | No |
| 53 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 11938 | -0.152 | -0.0519 | No |
| 54 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 12050 | -0.161 | -0.0474 | No |
| 55 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 12405 | -0.189 | -0.0590 | No |
| 56 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12528 | -0.202 | -0.0521 | No |
| 57 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 13275 | -0.526 | -0.0662 | No |
| 58 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 13330 | -0.892 | 0.0009 | No |
