Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetFLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN
Enrichment Score (ES)0.41022083
Normalized Enrichment Score (NES)1.7028275
Nominal p-value0.0
FDR q-value0.054057408
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CYP17A1CYP17A1
Entrez,  Source
cytochrome P450, family 17, subfamily A, polypeptide 121.6230.0289Yes
2SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4131.1950.0495Yes
3MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)310.9350.0650Yes
4DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)320.9250.0815Yes
5CD9CD9
Entrez,  Source
CD9 molecule410.8710.0965Yes
6ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 2510.8090.1103Yes
7CRYABCRYAB
Entrez,  Source
crystallin, alpha B620.7560.1230Yes
8GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)760.6970.1345Yes
9BBOX1BBOX1
Entrez,  Source
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1780.6950.1469Yes
10LGALS2LGALS2
Entrez,  Source
lectin, galactoside-binding, soluble, 2 (galectin 2)950.6720.1577Yes
11F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor1140.6250.1675Yes
12PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)1270.6100.1775Yes
13AZGP1AZGP1
Entrez,  Source
alpha-2-glycoprotein 1, zinc1290.6030.1882Yes
14PAHPAH
Entrez,  Source
phenylalanine hydroxylase1330.5970.1987Yes
15BEXL1BEXL1
Entrez,  Source
brain expressed X-linked-like 11350.5950.2093Yes
16FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 12030.4840.2128Yes
17USP2USP2
Entrez,  Source
ubiquitin specific peptidase 22070.4800.2211Yes
18FAHFAH
Entrez,  Source
fumarylacetoacetate hydrolase (fumarylacetoacetase)2320.4570.2275Yes
19GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)2420.4490.2348Yes
20DPYSDPYS
Entrez,  Source
dihydropyrimidinase2870.4100.2388Yes
21PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)2900.4080.2459Yes
22CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 12990.4020.2525Yes
23ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A13000.4020.2597Yes
24DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)3020.3990.2668Yes
25PCPC
Entrez,  Source
pyruvate carboxylase3220.3800.2721Yes
26RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma3230.3780.2789Yes
27SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 13360.3710.2846Yes
28ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial3460.3670.2905Yes
29G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit3470.3660.2970Yes
30ECH1ECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal3500.3650.3034Yes
31CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)3590.3590.3092Yes
32HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 43610.3580.3156Yes
33EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase3750.3490.3208Yes
34GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase3790.3480.3268Yes
35DEFB1DEFB1
Entrez,  Source
defensin, beta 14290.3220.3288Yes
36MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle4420.3130.3335Yes
37ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A25260.2770.3320Yes
38AHCYAHCY
Entrez,  Source
S-adenosylhomocysteine hydrolase5510.2690.3350Yes
39ASS1ASS1
Entrez,  Source
argininosuccinate synthetase 15560.2680.3395Yes
40PHYHPHYH
Entrez,  Source
phytanoyl-CoA 2-hydroxylase5660.2650.3435Yes
41ALDH5A1ALDH5A1
Entrez,  Source
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)5950.2580.3460Yes
42PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha6030.2570.3501Yes
43ABCD3ABCD3
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 36220.2510.3532Yes
44SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 46230.2510.3577Yes
45ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)6240.2510.3622Yes
46BPHLBPHL
Entrez,  Source
biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen)6520.2450.3645Yes
47HRSP12HRSP12
Entrez,  Source
heat-responsive protein 126540.2440.3687Yes
48ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)6580.2440.3729Yes
49AFMAFM
Entrez,  Source
afamin6810.2390.3755Yes
50APOMAPOM
Entrez,  Source
apolipoprotein M6870.2380.3793Yes
51GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)6900.2370.3834Yes
52PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D7310.2290.3844Yes
53GPC3GPC3
Entrez,  Source
glypican 37570.2240.3865Yes
54PEX3PEX3
Entrez,  Source
peroxisomal biogenesis factor 37600.2230.3904Yes
55GCHFRGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator7620.2230.3943Yes
56HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)7750.2210.3973Yes
57RNF14RNF14
Entrez,  Source
ring finger protein 148360.2070.3964Yes
58SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 58760.1990.3970Yes
59SCP2SCP2
Entrez,  Source
sterol carrier protein 28900.1970.3995Yes
60BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)9060.1950.4018Yes
61ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial9400.1890.4027Yes
62CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)9510.1880.4053Yes
63KLKL
Entrez,  Source
klotho9710.1860.4071Yes
64QPRTQPRT
Entrez,  Source
quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))10020.1820.4081Yes
65BHMTBHMT
Entrez,  Source
betaine-homocysteine methyltransferase10540.1770.4073Yes
66GPSN2GPSN2
Entrez,  Source
glycoprotein, synaptic 210580.1750.4102Yes
67EPHX2EPHX2
Entrez,  Source
epoxide hydrolase 2, cytoplasmic11080.1700.4095No
68PRODH2PRODH2
Entrez,  Source
proline dehydrogenase (oxidase) 211970.1610.4056No
69TACSTD1TACSTD1
Entrez,  Source
tumor-associated calcium signal transducer 112780.1530.4022No
70TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 213000.1500.4032No
71MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)13770.1440.4000No
72PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha14230.1410.3990No
73ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)14820.1360.3970No
74MAOBMAOB
Entrez,  Source
monoamine oxidase B15310.1330.3957No
75PRDX3PRDX3
Entrez,  Source
peroxiredoxin 315340.1320.3979No
76IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa15560.1310.3986No
77CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 116820.1240.3912No
78HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)16890.1230.3930No
79PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 716960.1230.3947No
80ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain17150.1220.3955No
81CBR4CBR4
Entrez,  Source
carbonyl reductase 417330.1210.3964No
82COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb17470.1190.3975No
83MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 117600.1190.3987No
84CRYMCRYM
Entrez,  Source
crystallin, mu18740.1130.3920No
85TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)19140.1110.3910No
86DZIP1DZIP1
Entrez,  Source
DAZ interacting protein 119600.1090.3895No
87TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)19690.1090.3908No
88APOHAPOH
Entrez,  Source
apolipoprotein H (beta-2-glycoprotein I)20110.1070.3896No
89RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 420640.1050.3875No
90CTHCTH
Entrez,  Source
cystathionase (cystathionine gamma-lyase)20880.1040.3875No
91ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)20900.1040.3893No
92CLINT1CLINT1
Entrez,  Source
clathrin interactor 121200.1030.3889No
93ALDOBALDOB
Entrez,  Source
aldolase B, fructose-bisphosphate21520.1010.3884No
94MAOAMAOA
Entrez,  Source
monoamine oxidase A21590.1010.3897No
95PRKRAPRKRA
Entrez,  Source
protein kinase, interferon-inducible double stranded RNA dependent activator21790.1000.3900No
96COMTCOMT
Entrez,  Source
catechol-O-methyltransferase22080.0990.3897No
97ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase23980.0920.3768No
98DDTDDT
Entrez,  Source
D-dopachrome tautomerase24530.0900.3742No
99CLTBCLTB
Entrez,  Source
clathrin, light chain (Lcb)24590.0890.3754No
100PDZK1IP1PDZK1IP1
Entrez,  Source
PDZK1 interacting protein 125120.0870.3730No
101CA4CA4
Entrez,  Source
carbonic anhydrase IV25140.0870.3745No
102FBXO9FBXO9
Entrez,  Source
F-box protein 925390.0860.3742No
103ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)25440.0860.3754No
104ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)25930.0840.3732No
105FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES26230.0830.3724No
106APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 226570.0820.3714No
107MDH1MDH1
Entrez,  Source
malate dehydrogenase 1, NAD (soluble)26740.0810.3716No
108DDCDDC
Entrez,  Source
dopa decarboxylase (aromatic L-amino acid decarboxylase)26920.0810.3717No
109ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1127060.0800.3721No
110ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F627380.0790.3712No
111CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)28480.0760.3641No
112ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A128930.0740.3621No
113ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl29470.0730.3593No
114ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)29520.0720.3603No
115HNMTHNMT
Entrez,  Source
histamine N-methyltransferase29860.0720.3590No
116HADHHADH
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase30830.0690.3528No
117FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase31020.0680.3527No
118IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble31610.0670.3494No
119RAB7L1RAB7L1
Entrez,  Source
RAB7, member RAS oncogene family-like 132070.0660.3471No
120ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)32090.0650.3482No
121CYCSCYCS
Entrez,  Source
cytochrome c, somatic32560.0640.3458No
122SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa33110.0620.3428No
123COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 433200.0620.3433No
124COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 133350.0620.3433No
125PPM1BPPM1B
Entrez,  Source
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform34220.0600.3377No
126NR1D2NR1D2
Entrez,  Source
nuclear receptor subfamily 1, group D, member 234310.0600.3382No
127AKR7A2AKR7A2
Entrez,  Source
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)34580.0590.3372No
128ACO1ACO1
Entrez,  Source
aconitase 1, soluble34620.0590.3381No
129DNM1LDNM1L
Entrez,  Source
dynamin 1-like34990.0580.3363No
130HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase36390.0540.3266No
131SLC22A2SLC22A2
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 236560.0530.3263No
132SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 236850.0530.3251No
133ABP1ABP1
Entrez,  Source
amiloride binding protein 1 (amine oxidase (copper-containing))37740.0510.3192No
134SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A37760.0510.3200No
135ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain37940.0500.3196No
136SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 138010.0500.3201No
137CALB1CALB1
Entrez,  Source
calbindin 1, 28kDa38470.0490.3175No
138IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor38900.0480.3151No
139ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)40050.0440.3071No
140BAMBIBAMBI
Entrez,  Source
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)40350.0440.3057No
141PRDX2PRDX2
Entrez,  Source
peroxiredoxin 240630.0430.3044No
142PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A41610.0410.2976No
143SULT1C1SULT1C1
Entrez,  Source
sulfotransferase family, cytosolic, 1C, member 141880.0400.2963No
144DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)41980.0400.2963No
145G3BPG3BP
Entrez,  Source
-42010.0390.2969No
146SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)42570.0380.2933No
147HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 243570.0370.2864No
148CLDN8CLDN8
Entrez,  Source
claudin 843820.0360.2852No
149ESRRGESRRG
Entrez,  Source
estrogen-related receptor gamma44020.0360.2844No
150KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)44420.0350.2820No
151CGRRF1CGRRF1
Entrez,  Source
cell growth regulator with ring finger domain 144450.0350.2824No
152SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 144690.0350.2813No
153KCNJ15KCNJ15
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1544700.0350.2819No
154IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 445780.0320.2742No
155ADH6ADH6
Entrez,  Source
alcohol dehydrogenase 6 (class V)46240.0320.2714No
156SC5DLSC5DL
Entrez,  Source
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like46440.0310.2704No
157PTPN3PTPN3
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 346940.0300.2672No
158PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)47500.0290.2635No
159NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47670.0290.2628No
160UGT8UGT8
Entrez,  Source
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)48120.0280.2599No
161ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle48840.0260.2549No
162PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform50550.0230.2422No
163SLC12A3SLC12A3
Entrez,  Source
solute carrier family 12 (sodium/chloride transporters), member 350800.0230.2408No
164PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)51230.0220.2379No
165SLC26A4SLC26A4
Entrez,  Source
solute carrier family 26, member 453610.0180.2200No
166FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)53810.0170.2188No
167FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C54360.0160.2149No
168UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II54870.0150.2114No
169MXI1MXI1
Entrez,  Source
MAX interactor 155230.0140.2089No
170SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 155630.0130.2062No
171LRPAP1LRPAP1
Entrez,  Source
low density lipoprotein receptor-related protein associated protein 157270.0100.1938No
172IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)57610.0100.1914No
173ADD3ADD3
Entrez,  Source
adducin 3 (gamma)58200.0090.1871No
174SLC7A8SLC7A8
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 858370.0080.1860No
175SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like58800.0080.1829No
176UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I59270.0070.1795No
177USP14USP14
Entrez,  Source
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)59280.0070.1796No
178PEX11BPEX11B
Entrez,  Source
peroxisomal biogenesis factor 11B59880.0050.1752No
179SCAMP1SCAMP1
Entrez,  Source
secretory carrier membrane protein 160040.0050.1741No
180NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa60090.0050.1739No
181UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 160100.0050.1740No
182DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 960820.0040.1686No
183DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase60880.0030.1683No
184FGF1FGF1
Entrez,  Source
fibroblast growth factor 1 (acidic)60940.0030.1679No
185SLC22A6SLC22A6
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 662300.0010.1576No
186PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 162710.0000.1545No
187ALBALB
Entrez,  Source
albumin62750.0000.1543No
188PFN2PFN2
Entrez,  Source
profilin 262810.0000.1539No
189NCKAP1NCKAP1
Entrez,  Source
NCK-associated protein 162840.0000.1537No
190DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)6342-0.0010.1493No
191MFAP3LMFAP3L
Entrez,  Source
microfibrillar-associated protein 3-like6343-0.0010.1494No
192IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 56450-0.0030.1412No
193HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase6481-0.0030.1390No
194CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)6484-0.0030.1389No
195HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)6540-0.0040.1347No
196ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)6582-0.0050.1317No
197RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family6729-0.0080.1206No
198PCBD1PCBD1
Entrez,  Source
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)6764-0.0080.1181No
199TOB1TOB1
Entrez,  Source
transducer of ERBB2, 16785-0.0090.1167No
200ACY1ACY1
Entrez,  Source
aminoacylase 16868-0.0100.1106No
201FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver6898-0.0100.1085No
202ITGA6ITGA6
Entrez,  Source
integrin, alpha 67051-0.0130.0971No
203HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)7083-0.0140.0949No
204OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase7089-0.0140.0948No
205SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7093-0.0140.0948No
206AQP1AQP1
Entrez,  Source
aquaporin 1 (Colton blood group)7239-0.0170.0839No
207CRYAACRYAA
Entrez,  Source
crystallin, alpha A7303-0.0180.0794No
208DSPDSP
Entrez,  Source
desmoplakin7304-0.0180.0797No
209PEX19PEX19
Entrez,  Source
peroxisomal biogenesis factor 197306-0.0180.0800No
210PHKBPHKB
Entrez,  Source
phosphorylase kinase, beta7355-0.0190.0766No
211ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487364-0.0190.0763No
212GPR116GPR116
Entrez,  Source
G protein-coupled receptor 1167368-0.0190.0764No
213CTSLCTSL
Entrez,  Source
cathepsin L7390-0.0200.0752No
214QDPRQDPR
Entrez,  Source
quinoid dihydropteridine reductase7441-0.0210.0717No
215TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 57449-0.0210.0715No
216CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 27503-0.0220.0678No
217PRKCIPRKCI
Entrez,  Source
protein kinase C, iota7723-0.0260.0514No
218PHBPHB
Entrez,  Source
prohibitin7736-0.0260.0510No
219SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)7827-0.0280.0445No
220DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 17972-0.0310.0340No
221HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit7978-0.0310.0341No
222PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase7997-0.0310.0333No
223SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)8001-0.0310.0336No
224CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)8008-0.0310.0337No
225SERINC1SERINC1
Entrez,  Source
serine incorporator 18027-0.0320.0329No
226PGM1PGM1
Entrez,  Source
phosphoglucomutase 18051-0.0320.0317No
227AP3D1AP3D1
Entrez,  Source
adaptor-related protein complex 3, delta 1 subunit8055-0.0320.0321No
228CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 28129-0.0340.0271No
229HIBCHHIBCH
Entrez,  Source
3-hydroxyisobutyryl-Coenzyme A hydrolase8146-0.0340.0264No
230TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)8177-0.0350.0248No
231NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)8263-0.0370.0189No
232DAPDAP
Entrez,  Source
death-associated protein8268-0.0370.0192No
233MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle8278-0.0370.0192No
234RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A8307-0.0370.0177No
235NQO2NQO2
Entrez,  Source
NAD(P)H dehydrogenase, quinone 28329-0.0380.0168No
236STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 38342-0.0380.0165No
237WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 18375-0.0390.0148No
238VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 28408-0.0400.0130No
239PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)8424-0.0400.0126No
240PPP2R1APPP2R1A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform8432-0.0400.0127No
241CYB5R3CYB5R3
Entrez,  Source
cytochrome b5 reductase 38531-0.0420.0059No
242EFHA1EFHA1
Entrez,  Source
EF-hand domain family, member A18541-0.0420.0060No
243ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 28616-0.0440.0011No
244SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 18681-0.045-0.0030No
245YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8704-0.045-0.0039No
246ITM2BITM2B
Entrez,  Source
integral membrane protein 2B8720-0.046-0.0042No
247HBLD2HBLD2
Entrez,  Source
HESB like domain containing 28732-0.046-0.0043No
248PJA2PJA2
Entrez,  Source
praja 2, RING-H2 motif containing8736-0.046-0.0037No
249CATCAT
Entrez,  Source
catalase8873-0.049-0.0133No
250AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)8947-0.051-0.0180No
251LRP2LRP2
Entrez,  Source
low density lipoprotein-related protein 28982-0.051-0.0197No
252PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 29059-0.053-0.0246No
253PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta9068-0.053-0.0242No
254GLSGLS
Entrez,  Source
glutaminase9073-0.053-0.0236No
255SHANK2SHANK2
Entrez,  Source
SH3 and multiple ankyrin repeat domains 29084-0.054-0.0234No
256PLGPLG
Entrez,  Source
plasminogen9113-0.054-0.0246No
257TEGTTEGT
Entrez,  Source
testis enhanced gene transcript (BAX inhibitor 1)9169-0.055-0.0278No
258TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)9181-0.056-0.0277No
259ANKRD46ANKRD46
Entrez,  Source
ankyrin repeat domain 469239-0.057-0.0311No
260GHITMGHITM
Entrez,  Source
growth hormone inducible transmembrane protein9256-0.057-0.0313No
261HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)9296-0.058-0.0332No
262PGRMC1PGRMC1
Entrez,  Source
progesterone receptor membrane component 19378-0.060-0.0384No
263HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 89449-0.062-0.0427No
264GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 19461-0.062-0.0424No
265PODXLPODXL
Entrez,  Source
podocalyxin-like9478-0.062-0.0425No
266AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)9501-0.063-0.0431No
267DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked9594-0.065-0.0490No
268VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 19595-0.065-0.0479No
269COPS5COPS5
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)9599-0.065-0.0469No
270STCHSTCH
Entrez,  Source
stress 70 protein chaperone, microsome-associated, 60kDa9623-0.066-0.0475No
271HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 19698-0.068-0.0520No
272TSPYL4TSPYL4
Entrez,  Source
TSPY-like 49720-0.069-0.0524No
273PEBP1PEBP1
Entrez,  Source
phosphatidylethanolamine binding protein 19842-0.072-0.0604No
274BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 39855-0.073-0.0600No
275ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 29965-0.075-0.0671No
276MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 210054-0.078-0.0725No
277COPS2COPS2
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)10059-0.078-0.0714No
278CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10104-0.079-0.0733No
279RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family10106-0.079-0.0720No
280RFKRFK
Entrez,  Source
riboflavin kinase10120-0.080-0.0716No
281SNRPN /// SNURF10197-0.082-0.0760No
282COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha10279-0.084-0.0807No
283RDXRDX
Entrez,  Source
radixin10400-0.087-0.0884No
284GRB14GRB14
Entrez,  Source
growth factor receptor-bound protein 1410443-0.089-0.0900No
285CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10674-0.096-0.1060No
286CA2CA2
Entrez,  Source
carbonic anhydrase II10759-0.099-0.1107No
287GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)10782-0.100-0.1106No
288NEK4NEK4
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 410801-0.101-0.1102No
289FOLH1FOLH1
Entrez,  Source
folate hydrolase (prostate-specific membrane antigen) 110825-0.102-0.1101No
290ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)10917-0.106-0.1153No
291C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein10931-0.106-0.1144No
292ANXA7ANXA7
Entrez,  Source
annexin A710981-0.108-0.1162No
293NR3C2NR3C2
Entrez,  Source
nuclear receptor subfamily 3, group C, member 211091-0.112-0.1226No
294SORDSORD
Entrez,  Source
sorbitol dehydrogenase11093-0.112-0.1207No
295LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing11099-0.112-0.1191No
296HRASLS3HRASLS3
Entrez,  Source
HRAS-like suppressor 311191-0.116-0.1240No
297RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit11200-0.116-0.1225No
298STRAPSTRAP
Entrez,  Source
serine/threonine kinase receptor associated protein11237-0.117-0.1232No
299NARSNARS
Entrez,  Source
asparaginyl-tRNA synthetase11247-0.118-0.1218No
300KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)11294-0.120-0.1232No
301PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)11304-0.121-0.1217No
302MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein11344-0.122-0.1225No
303ACPPACPP
Entrez,  Source
acid phosphatase, prostate11357-0.123-0.1213No
304SERBP1SERBP1
Entrez,  Source
SERPINE1 mRNA binding protein 111399-0.125-0.1222No
305PCBP2PCBP2
Entrez,  Source
poly(rC) binding protein 211406-0.125-0.1204No
306IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 211426-0.126-0.1196No
307MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B11505-0.129-0.1233No
308RTN4RTN4
Entrez,  Source
reticulon 411618-0.135-0.1295No
309CFDP1CFDP1
Entrez,  Source
craniofacial development protein 111738-0.140-0.1362No
310TSC22D1TSC22D1
Entrez,  Source
TSC22 domain family, member 111757-0.142-0.1350No
311OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)11781-0.143-0.1342No
312CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211792-0.144-0.1324No
313ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1511802-0.145-0.1305No
314PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa11805-0.145-0.1281No
315PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)11830-0.146-0.1273No
316SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 711894-0.150-0.1295No
317HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)11910-0.150-0.1280No
318WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)11948-0.154-0.1281No
319MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)11986-0.156-0.1281No
320AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1112060-0.162-0.1309No
321AK3L1AK3L1
Entrez,  Source
adenylate kinase 3-like 112108-0.165-0.1315No
322PGK1PGK1
Entrez,  Source
phosphoglycerate kinase 112194-0.171-0.1350No
323FMR1FMR1
Entrez,  Source
fragile X mental retardation 112198-0.171-0.1322No
324VEGFVEGF
Entrez,  Source
vascular endothelial growth factor12221-0.173-0.1308No
325PDZK1PDZK1
Entrez,  Source
PDZ domain containing 112224-0.173-0.1278No
326NAT8NAT8
Entrez,  Source
N-acetyltransferase 8 (camello like)12276-0.177-0.1286No
327ST13ST13
Entrez,  Source
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)12397-0.188-0.1345No
328SDC1SDC1
Entrez,  Source
syndecan 112438-0.192-0.1341No
329EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 212468-0.195-0.1328No
330PRPSAP2PRPSAP2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase-associated protein 212563-0.206-0.1364No
331PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)12567-0.207-0.1329No
332TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)12582-0.208-0.1303No
333GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12617-0.213-0.1291No
334ATF2ATF2
Entrez,  Source
activating transcription factor 212642-0.216-0.1270No
335KIF3AKIF3A
Entrez,  Source
kinesin family member 3A12663-0.219-0.1247No
336SMAD5SMAD5
Entrez,  Source
SMAD, mothers against DPP homolog 5 (Drosophila)12778-0.238-0.1292No
337GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)12796-0.240-0.1262No
338FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 112848-0.253-0.1256No
339VAT1VAT1
Entrez,  Source
vesicle amine transport protein 1 homolog (T californica)12879-0.262-0.1232No
340SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 112983-0.288-0.1260No
341PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 512986-0.289-0.1210No
342SLC4A4SLC4A4
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 413008-0.294-0.1173No
343SLC13A3SLC13A3
Entrez,  Source
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 313078-0.318-0.1169No
344HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 113125-0.341-0.1144No
345UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase13138-0.352-0.1090No
346CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 413159-0.370-0.1039No
347ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 313175-0.381-0.0983No
348ENTPD5ENTPD5
Entrez,  Source
ectonucleoside triphosphate diphosphohydrolase 513183-0.385-0.0919No
349XPNPEP2XPNPEP2
Entrez,  Source
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound13200-0.402-0.0859No
350TNPO1TNPO1
Entrez,  Source
transportin 113223-0.430-0.0799No
351AKR7A3AKR7A3
Entrez,  Source
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)13236-0.447-0.0729No
352NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113268-0.519-0.0660No
353ABCC4ABCC4
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 413272-0.523-0.0568No
354SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 213274-0.526-0.0475No
355SLC17A1SLC17A1
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 113290-0.561-0.0386No
356GSTA2GSTA2
Entrez,  Source
glutathione S-transferase A213300-0.608-0.0284No
357SLC17A3SLC17A3
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 313320-0.761-0.0162No
358RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)13333-0.9980.0007No
Table: GSEA details [plain text format]



Fig 2: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN: Random ES distribution   
Gene set null distribution of ES for FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN