Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | GLYCOLYSIS_AND_GLUCONEOGENESIS |
| Enrichment Score (ES) | 0.62690705 |
| Normalized Enrichment Score (NES) | 1.8048929 |
| Nominal p-value | 0.0018018018 |
| FDR q-value | 0.027541203 |
| FWER p-Value | 0.929 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 15 | 1.102 | 0.1545 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.2484 | Yes |
| 3 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 127 | 0.610 | 0.3308 | Yes |
| 4 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 203 | 0.484 | 0.3936 | Yes |
| 5 | PC | PC Entrez, Source | pyruvate carboxylase | 322 | 0.380 | 0.4385 | Yes |
| 6 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 347 | 0.366 | 0.4884 | Yes |
| 7 | HK1 | HK1 Entrez, Source | hexokinase 1 | 385 | 0.345 | 0.5344 | Yes |
| 8 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 401 | 0.337 | 0.5809 | Yes |
| 9 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 411 | 0.331 | 0.6269 | Yes |
| 10 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 1026 | 0.179 | 0.6061 | No |
| 11 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 1889 | 0.112 | 0.5571 | No |
| 12 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 2152 | 0.101 | 0.5518 | No |
| 13 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 2165 | 0.101 | 0.5651 | No |
| 14 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 2249 | 0.097 | 0.5726 | No |
| 15 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2674 | 0.081 | 0.5522 | No |
| 16 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 2860 | 0.075 | 0.5490 | No |
| 17 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 3477 | 0.058 | 0.5109 | No |
| 18 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 3755 | 0.051 | 0.4973 | No |
| 19 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 4179 | 0.040 | 0.4712 | No |
| 20 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 5039 | 0.023 | 0.4099 | No |
| 21 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 5889 | 0.007 | 0.3471 | No |
| 22 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 6088 | 0.003 | 0.3327 | No |
| 23 | HK2 | HK2 Entrez, Source | hexokinase 2 | 6340 | -0.001 | 0.3140 | No |
| 24 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 6466 | -0.003 | 0.3050 | No |
| 25 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 7034 | -0.013 | 0.2642 | No |
| 26 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 7619 | -0.024 | 0.2237 | No |
| 27 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9641 | -0.066 | 0.0812 | No |
| 28 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 9934 | -0.075 | 0.0698 | No |
| 29 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 10001 | -0.077 | 0.0757 | No |
| 30 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 10093 | -0.079 | 0.0800 | No |
| 31 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 10232 | -0.083 | 0.0813 | No |
| 32 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 11125 | -0.113 | 0.0302 | No |
| 33 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 11369 | -0.123 | 0.0294 | No |
| 34 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 12067 | -0.162 | -0.0001 | No |
| 35 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 12194 | -0.171 | 0.0145 | No |
| 36 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 12501 | -0.200 | 0.0197 | No |
| 37 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 13052 | -0.307 | 0.0218 | No |
