Details for gene set GTPASE_REGULATOR

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	GTPASE_REGULATOR_ACTIVITY
Enrichment Score (ES)	0.53906363
Normalized Enrichment Score (NES)	1.7820845
Nominal p-value	0.0016750419
FDR q-value	0.03195883
FWER p-Value	0.973

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	50	0.810	0.0785	Yes
2	RGS1	RGS1 Entrez, Source	regulator of G-protein signalling 1	73	0.715	0.1495	Yes
3	RGS5	RGS5 Entrez, Source	regulator of G-protein signalling 5	125	0.616	0.2083	Yes
4	ALDH1A1	ALDH1A1 Entrez, Source	aldehyde dehydrogenase 1 family, member A1	185	0.510	0.2557	Yes
5	RGS16	RGS16 Entrez, Source	regulator of G-protein signalling 16	205	0.482	0.3033	Yes
6	RGS3	RGS3 Entrez, Source	regulator of G-protein signalling 3	301	0.402	0.3370	Yes
7	RAPGEF5	RAPGEF5 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 5	331	0.373	0.3727	Yes
8	RAPGEF4	RAPGEF4 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 4	333	0.373	0.4105	Yes
9	PLCE1	PLCE1 Entrez, Source	phospholipase C, epsilon 1	396	0.339	0.4403	Yes
10	CDC42EP2	CDC42EP2 Entrez, Source	CDC42 effector protein (Rho GTPase binding) 2	399	0.337	0.4744	Yes
11	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	639	0.247	0.4815	Yes
12	TNK2	TNK2 Entrez, Source	tyrosine kinase, non-receptor, 2	715	0.232	0.4994	Yes
13	PSCD1	PSCD1 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)	789	0.217	0.5159	Yes
14	CDC42SE1	CDC42SE1 Entrez, Source	CDC42 small effector 1	975	0.186	0.5208	Yes
15	EIF2B2	EIF2B2 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	1156	0.164	0.5240	Yes
16	RTKN	RTKN Entrez, Source	rhotekin	1233	0.158	0.5343	Yes
17	RALBP1	RALBP1 Entrez, Source	ralA binding protein 1	1617	0.127	0.5183	Yes
18	NET1	NET1 Entrez, Source	neuroepithelial cell transforming gene 1	1732	0.121	0.5220	Yes
19	RASGRP4	RASGRP4 Entrez, Source	RAS guanyl releasing protein 4	1827	0.116	0.5267	Yes
20	RIMS1	RIMS1 Entrez, Source	regulating synaptic membrane exocytosis 1	1929	0.110	0.5303	Yes
21	PSCD2	PSCD2 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)	1961	0.109	0.5391	Yes
22	ARHGDIB	ARHGDIB Entrez, Source	Rho GDP dissociation inhibitor (GDI) beta	2541	0.086	0.5042	No
23	RALGDS	RALGDS Entrez, Source	ral guanine nucleotide dissociation stimulator	2680	0.081	0.5020	No
24	RCBTB2	RCBTB2 Entrez, Source	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	2710	0.080	0.5079	No
25	CENTA1	CENTA1 Entrez, Source	centaurin, alpha 1	3167	0.067	0.4803	No
26	FGD1	FGD1 Entrez, Source	FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia)	3218	0.065	0.4832	No
27	PSCD3	PSCD3 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 3	3279	0.063	0.4851	No
28	RGS6	RGS6 Entrez, Source	regulator of G-protein signalling 6	3368	0.061	0.4847	No
29	ERRFI1	ERRFI1 Entrez, Source	ERBB receptor feedback inhibitor 1	3633	0.054	0.4703	No
30	ARHGEF1	ARHGEF1 Entrez, Source	Rho guanine nucleotide exchange factor (GEF) 1	3915	0.047	0.4539	No
31	WASL	WASL Entrez, Source	Wiskott-Aldrich syndrome-like	4230	0.039	0.4341	No
32	RAPGEF3	RAPGEF3 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 3	4278	0.038	0.4345	No
33	THY1	THY1 Entrez, Source	Thy-1 cell surface antigen	4478	0.034	0.4230	No
34	ARHGAP4	ARHGAP4 Entrez, Source	Rho GTPase activating protein 4	4793	0.028	0.4022	No
35	RAP1GAP	RAP1GAP Entrez, Source	RAP1 GTPase activating protein	5106	0.022	0.3809	No
36	EIF2B1	EIF2B1 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	5418	0.016	0.3591	No
37	ALS2	ALS2 Entrez, Source	amyotrophic lateral sclerosis 2 (juvenile)	5840	0.008	0.3283	No
38	RGS9	RGS9 Entrez, Source	regulator of G-protein signalling 9	5873	0.008	0.3266	No
39	ARHGAP27	ARHGAP27 Entrez, Source	Rho GTPase activating protein 27	6001	0.005	0.3176	No
40	CENTD2	CENTD2 Entrez, Source	centaurin, delta 2	6123	0.003	0.3088	No
41	DLC1	DLC1 Entrez, Source	deleted in liver cancer 1	6645	-0.006	0.2702	No
42	RGS12	RGS12 Entrez, Source	regulator of G-protein signalling 12	6660	-0.007	0.2698	No
43	ARL2BP	ARL2BP Entrez, Source	ADP-ribosylation factor-like 2 binding protein	7379	-0.019	0.2177	No
44	KALRN	KALRN Entrez, Source	kalirin, RhoGEF kinase	7433	-0.020	0.2157	No
45	ARHGEF2	ARHGEF2 Entrez, Source	rho/rac guanine nucleotide exchange factor (GEF) 2	7553	-0.023	0.2091	No
46	GDI2	GDI2 Entrez, Source	GDP dissociation inhibitor 2	7674	-0.025	0.2026	No
47	EIF2B4	EIF2B4 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	8097	-0.033	0.1742	No
48	RGS14	RGS14 Entrez, Source	regulator of G-protein signalling 14	8231	-0.036	0.1678	No
49	FGD4	FGD4 Entrez, Source	FYVE, RhoGEF and PH domain containing 4	8475	-0.041	0.1537	No
50	CHN2	CHN2 Entrez, Source	chimerin (chimaerin) 2	8642	-0.044	0.1457	No
51	ARHGEF11	ARHGEF11 Entrez, Source	Rho guanine nucleotide exchange factor (GEF) 11	8717	-0.046	0.1447	No
52	ARHGAP5	ARHGAP5 Entrez, Source	Rho GTPase activating protein 5	9336	-0.059	0.1042	No
53	RASA2	RASA2 Entrez, Source	RAS p21 protein activator 2	9408	-0.061	0.1050	No
54	TIAM1	TIAM1 Entrez, Source	T-cell lymphoma invasion and metastasis 1	9463	-0.062	0.1072	No
55	EIF2B3	EIF2B3 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	9514	-0.063	0.1099	No
56	RAB3GAP2	RAB3GAP2 Entrez, Source	RAB3 GTPase activating protein subunit 2 (non-catalytic)	9593	-0.065	0.1106	No
57	MADD	MADD Entrez, Source	MAP-kinase activating death domain	10009	-0.077	0.0872	No
58	GPS1	GPS1 Entrez, Source	G protein pathway suppressor 1	10011	-0.077	0.0949	No
59	ARL2	ARL2 Entrez, Source	ADP-ribosylation factor-like 2	10161	-0.081	0.0919	No
60	NF1	NF1 Entrez, Source	neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)	10565	-0.092	0.0709	No
61	RANGAP1	RANGAP1 Entrez, Source	Ran GTPase activating protein 1	10704	-0.097	0.0704	No
62	TSC2	TSC2 Entrez, Source	tuberous sclerosis 2	10848	-0.103	0.0700	No
63	SIPA1	SIPA1 Entrez, Source	signal-induced proliferation-associated gene 1	11004	-0.108	0.0694	No
64	RASA3	RASA3 Entrez, Source	RAS p21 protein activator 3	11272	-0.119	0.0614	No
65	MYO9B	MYO9B Entrez, Source	myosin IXB	11288	-0.120	0.0724	No
66	ARHGDIA	ARHGDIA Entrez, Source	Rho GDP dissociation inhibitor (GDI) alpha	11482	-0.128	0.0709	No
67	RASA1	RASA1 Entrez, Source	RAS p21 protein activator (GTPase activating protein) 1	11793	-0.144	0.0622	No
68	EIF2B5	EIF2B5 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	12772	-0.237	0.0126	No
69	TRIO	TRIO Entrez, Source	triple functional domain (PTPRF interacting)	13021	-0.298	0.0242	No