Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HOFFMANN_BIVSBII_BI |
| Enrichment Score (ES) | 0.5909592 |
| Normalized Enrichment Score (NES) | 1.9241921 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010101566 |
| FWER p-Value | 0.408 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 21 | 1.039 | 0.0978 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 25 | 0.995 | 0.1928 | Yes |
| 3 | CD9 | CD9 Entrez, Source | CD9 molecule | 41 | 0.871 | 0.2751 | Yes |
| 4 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 119 | 0.621 | 0.3288 | Yes |
| 5 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 159 | 0.550 | 0.3786 | Yes |
| 6 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 164 | 0.541 | 0.4301 | Yes |
| 7 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 356 | 0.362 | 0.4503 | Yes |
| 8 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 407 | 0.334 | 0.4785 | Yes |
| 9 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 433 | 0.319 | 0.5072 | Yes |
| 10 | SQLE | SQLE Entrez, Source | squalene epoxidase | 446 | 0.311 | 0.5361 | Yes |
| 11 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 592 | 0.258 | 0.5499 | Yes |
| 12 | ITM2C | ITM2C Entrez, Source | integral membrane protein 2C | 741 | 0.229 | 0.5607 | Yes |
| 13 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 824 | 0.209 | 0.5745 | Yes |
| 14 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1133 | 0.167 | 0.5673 | Yes |
| 15 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 1191 | 0.162 | 0.5785 | Yes |
| 16 | AKR1C6 | 1356 | 0.146 | 0.5801 | Yes | ||
| 17 | EMB | EMB Entrez, Source | embigin homolog (mouse) | 1474 | 0.137 | 0.5844 | Yes |
| 18 | HEMGN | HEMGN Entrez, Source | hemogen | 1555 | 0.131 | 0.5910 | Yes |
| 19 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 1729 | 0.121 | 0.5895 | No |
| 20 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 1973 | 0.109 | 0.5817 | No |
| 21 | PIK4CB | PIK4CB Entrez, Source | phosphatidylinositol 4-kinase, catalytic, beta polypeptide | 2328 | 0.094 | 0.5640 | No |
| 22 | ADA | ADA Entrez, Source | adenosine deaminase | 2355 | 0.093 | 0.5710 | No |
| 23 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 2432 | 0.090 | 0.5739 | No |
| 24 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3280 | 0.063 | 0.5162 | No |
| 25 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 3460 | 0.059 | 0.5083 | No |
| 26 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 3697 | 0.052 | 0.4956 | No |
| 27 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 3904 | 0.047 | 0.4846 | No |
| 28 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4187 | 0.040 | 0.4671 | No |
| 29 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 4246 | 0.039 | 0.4665 | No |
| 30 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 4443 | 0.035 | 0.4551 | No |
| 31 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 4478 | 0.034 | 0.4558 | No |
| 32 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 4549 | 0.033 | 0.4537 | No |
| 33 | TAX1BP3 | TAX1BP3 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 4614 | 0.032 | 0.4519 | No |
| 34 | CUBN | CUBN Entrez, Source | cubilin (intrinsic factor-cobalamin receptor) | 4696 | 0.030 | 0.4487 | No |
| 35 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 4716 | 0.030 | 0.4501 | No |
| 36 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 4984 | 0.024 | 0.4323 | No |
| 37 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 5302 | 0.019 | 0.4103 | No |
| 38 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 5835 | 0.008 | 0.3710 | No |
| 39 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 6245 | 0.001 | 0.3403 | No |
| 40 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 6336 | -0.001 | 0.3335 | No |
| 41 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 6393 | -0.002 | 0.3295 | No |
| 42 | TLOC1 | TLOC1 Entrez, Source | translocation protein 1 | 6544 | -0.005 | 0.3186 | No |
| 43 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 6695 | -0.007 | 0.3080 | No |
| 44 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 7240 | -0.017 | 0.2686 | No |
| 45 | CRYAA | CRYAA Entrez, Source | crystallin, alpha A | 7303 | -0.018 | 0.2657 | No |
| 46 | CTSL | CTSL Entrez, Source | cathepsin L | 7390 | -0.020 | 0.2611 | No |
| 47 | GIMAP4 | GIMAP4 Entrez, Source | GTPase, IMAP family member 4 | 7523 | -0.022 | 0.2532 | No |
| 48 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 7965 | -0.031 | 0.2230 | No |
| 49 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 8088 | -0.033 | 0.2170 | No |
| 50 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 8557 | -0.043 | 0.1858 | No |
| 51 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 8654 | -0.044 | 0.1828 | No |
| 52 | ENPP1 | ENPP1 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 9193 | -0.056 | 0.1476 | No |
| 53 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 10321 | -0.085 | 0.0709 | No |
| 54 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 10420 | -0.088 | 0.0720 | No |
| 55 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 10439 | -0.088 | 0.0791 | No |
| 56 | ZYX | ZYX Entrez, Source | zyxin | 10834 | -0.102 | 0.0592 | No |
| 57 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 11004 | -0.108 | 0.0568 | No |
| 58 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 11119 | -0.113 | 0.0591 | No |
| 59 | MAPK8IP3 | MAPK8IP3 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 3 | 12138 | -0.167 | -0.0016 | No |
| 60 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12178 | -0.170 | 0.0117 | No |
| 61 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12736 | -0.231 | -0.0082 | No |
| 62 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 12799 | -0.241 | 0.0102 | No |
| 63 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 13083 | -0.319 | 0.0195 | No |
