Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HOFFMANN_BIVSBII_BI_TABLE2 |
| Enrichment Score (ES) | -0.35842133 |
| Normalized Enrichment Score (NES) | -1.4072634 |
| Nominal p-value | 0.005319149 |
| FDR q-value | 0.2895664 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.0458 | No |
| 2 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 136 | 0.594 | 0.0852 | No |
| 3 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 323 | 0.378 | 0.0991 | No |
| 4 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 592 | 0.258 | 0.0979 | No |
| 5 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 666 | 0.242 | 0.1103 | No |
| 6 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 823 | 0.209 | 0.1140 | No |
| 7 | IER3 | IER3 Entrez, Source | immediate early response 3 | 908 | 0.195 | 0.1221 | No |
| 8 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 1025 | 0.179 | 0.1266 | No |
| 9 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 1116 | 0.169 | 0.1323 | No |
| 10 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 1262 | 0.155 | 0.1327 | No |
| 11 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1319 | 0.149 | 0.1395 | No |
| 12 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 1790 | 0.117 | 0.1127 | No |
| 13 | E2F8 | E2F8 Entrez, Source | E2F transcription factor 8 | 2573 | 0.084 | 0.0598 | No |
| 14 | SPIN | SPIN Entrez, Source | spindlin | 2620 | 0.083 | 0.0624 | No |
| 15 | RAB4B | RAB4B Entrez, Source | RAB4B, member RAS oncogene family | 2646 | 0.082 | 0.0666 | No |
| 16 | CDC2A | 2741 | 0.079 | 0.0653 | No | ||
| 17 | ARL1 | ARL1 Entrez, Source | ADP-ribosylation factor-like 1 | 2794 | 0.077 | 0.0671 | No |
| 18 | CD2 | CD2 Entrez, Source | CD2 molecule | 2852 | 0.076 | 0.0684 | No |
| 19 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 2891 | 0.074 | 0.0710 | No |
| 20 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 3049 | 0.070 | 0.0643 | No |
| 21 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 3138 | 0.068 | 0.0626 | No |
| 22 | IGSF10 | IGSF10 Entrez, Source | immunoglobulin superfamily, member 10 | 3162 | 0.067 | 0.0658 | No |
| 23 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 3176 | 0.066 | 0.0698 | No |
| 24 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 3937 | 0.046 | 0.0157 | No |
| 25 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.0034 | No |
| 26 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 4248 | 0.038 | -0.0019 | No |
| 27 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 4315 | 0.037 | -0.0042 | No |
| 28 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4357 | 0.037 | -0.0046 | No |
| 29 | RELN | RELN Entrez, Source | reelin | 4416 | 0.035 | -0.0063 | No |
| 30 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 4440 | 0.035 | -0.0055 | No |
| 31 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 4606 | 0.032 | -0.0156 | No |
| 32 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 4726 | 0.030 | -0.0224 | No |
| 33 | NT5DC2 | NT5DC2 Entrez, Source | 5'-nucleotidase domain containing 2 | 4819 | 0.028 | -0.0273 | No |
| 34 | PPIA | PPIA Entrez, Source | peptidylprolyl isomerase A (cyclophilin A) | 5079 | 0.023 | -0.0452 | No |
| 35 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 5186 | 0.020 | -0.0517 | No |
| 36 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 5302 | 0.019 | -0.0590 | No |
| 37 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 5550 | 0.014 | -0.0767 | No |
| 38 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5660 | 0.012 | -0.0841 | No |
| 39 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 5689 | 0.011 | -0.0854 | No |
| 40 | WDSUB1 | WDSUB1 Entrez, Source | WD repeat, sterile alpha motif and U-box domain containing 1 | 5726 | 0.010 | -0.0873 | No |
| 41 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5789 | 0.009 | -0.0913 | No |
| 42 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 5809 | 0.009 | -0.0921 | No |
| 43 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5816 | 0.009 | -0.0919 | No |
| 44 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 6273 | 0.000 | -0.1264 | No |
| 45 | LIPC | LIPC Entrez, Source | lipase, hepatic | 6430 | -0.002 | -0.1380 | No |
| 46 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 6459 | -0.003 | -0.1399 | No |
| 47 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6502 | -0.004 | -0.1428 | No |
| 48 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6540 | -0.004 | -0.1453 | No |
| 49 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6582 | -0.005 | -0.1480 | No |
| 50 | JUN | JUN Entrez, Source | jun oncogene | 6649 | -0.006 | -0.1525 | No |
| 51 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 6695 | -0.007 | -0.1554 | No |
| 52 | NELF | NELF Entrez, Source | nasal embryonic LHRH factor | 6908 | -0.011 | -0.1706 | No |
| 53 | CD151 | CD151 Entrez, Source | CD151 molecule (Raph blood group) | 6998 | -0.012 | -0.1765 | No |
| 54 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 7034 | -0.013 | -0.1781 | No |
| 55 | GPHN | GPHN Entrez, Source | gephyrin | 7196 | -0.016 | -0.1891 | No |
| 56 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 7240 | -0.017 | -0.1912 | No |
| 57 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 7762 | -0.027 | -0.2286 | No |
| 58 | CHAF1B | CHAF1B Entrez, Source | chromatin assembly factor 1, subunit B (p60) | 7839 | -0.028 | -0.2323 | No |
| 59 | COIL | COIL Entrez, Source | coilin | 7869 | -0.029 | -0.2323 | No |
| 60 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 8278 | -0.037 | -0.2605 | No |
| 61 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 8349 | -0.038 | -0.2629 | No |
| 62 | IGH-1A | 8420 | -0.040 | -0.2653 | No | ||
| 63 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 8463 | -0.041 | -0.2654 | No |
| 64 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.2631 | No |
| 65 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 8537 | -0.042 | -0.2647 | No |
| 66 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 8545 | -0.042 | -0.2621 | No |
| 67 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 8632 | -0.044 | -0.2654 | No |
| 68 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | -0.2660 | No |
| 69 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 8702 | -0.045 | -0.2638 | No |
| 70 | FLIIH | 8714 | -0.046 | -0.2613 | No | ||
| 71 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 8855 | -0.049 | -0.2682 | No |
| 72 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 8941 | -0.051 | -0.2709 | No |
| 73 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 9093 | -0.054 | -0.2783 | No |
| 74 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 9094 | -0.054 | -0.2744 | No |
| 75 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 9146 | -0.055 | -0.2742 | No |
| 76 | AZIN1 | AZIN1 Entrez, Source | antizyme inhibitor 1 | 9225 | -0.057 | -0.2759 | No |
| 77 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 9312 | -0.058 | -0.2781 | No |
| 78 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 9335 | -0.059 | -0.2754 | No |
| 79 | HDH | 9410 | -0.061 | -0.2765 | No | ||
| 80 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 9610 | -0.066 | -0.2867 | No |
| 81 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 9934 | -0.075 | -0.3056 | No |
| 82 | NUCKS1 | NUCKS1 Entrez, Source | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 10065 | -0.078 | -0.3096 | No |
| 83 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 10439 | -0.088 | -0.3313 | No |
| 84 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.3348 | No |
| 85 | IDE | IDE Entrez, Source | insulin-degrading enzyme | 10616 | -0.094 | -0.3307 | No |
| 86 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 10772 | -0.100 | -0.3350 | No |
| 87 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 10956 | -0.107 | -0.3410 | No |
| 88 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 11106 | -0.112 | -0.3439 | No |
| 89 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 11114 | -0.113 | -0.3361 | No |
| 90 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11410 | -0.125 | -0.3492 | Yes |
| 91 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11434 | -0.126 | -0.3416 | Yes |
| 92 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 11613 | -0.134 | -0.3451 | Yes |
| 93 | IL4 | IL4 Entrez, Source | interleukin 4 | 11640 | -0.135 | -0.3371 | Yes |
| 94 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11666 | -0.137 | -0.3288 | Yes |
| 95 | AURKB | AURKB Entrez, Source | aurora kinase B | 11946 | -0.153 | -0.3386 | Yes |
| 96 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12163 | -0.169 | -0.3425 | Yes |
| 97 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 12215 | -0.173 | -0.3336 | Yes |
| 98 | ANP32B | ANP32B Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 12233 | -0.174 | -0.3220 | Yes |
| 99 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12234 | -0.174 | -0.3091 | Yes |
| 100 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 12237 | -0.175 | -0.2963 | Yes |
| 101 | AURKA | AURKA Entrez, Source | aurora kinase A | 12238 | -0.175 | -0.2834 | Yes |
| 102 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.2708 | Yes |
| 103 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 12473 | -0.196 | -0.2736 | Yes |
| 104 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.2749 | Yes |
| 105 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 12799 | -0.241 | -0.2636 | Yes |
| 106 | TUBB | TUBB Entrez, Source | tubulin, beta | 12860 | -0.256 | -0.2492 | Yes |
| 107 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12917 | -0.270 | -0.2335 | Yes |
| 108 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 12918 | -0.270 | -0.2135 | Yes |
| 109 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12933 | -0.273 | -0.1944 | Yes |
| 110 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.1762 | Yes |
| 111 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1564 | Yes |
| 112 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 13111 | -0.334 | -0.1405 | Yes |
| 113 | TUBB3 | TUBB3 Entrez, Source | tubulin, beta 3 | 13124 | -0.340 | -0.1162 | Yes |
| 114 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 13130 | -0.345 | -0.0911 | Yes |
| 115 | LGALS3 | LGALS3 Entrez, Source | lectin, galactoside-binding, soluble, 3 (galectin 3) | 13142 | -0.354 | -0.0657 | Yes |
| 116 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13280 | -0.538 | -0.0363 | Yes |
| 117 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
