Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00010_GLYCOLYSIS_AND_GLUCONEOGENESIS |
| Enrichment Score (ES) | 0.54560685 |
| Normalized Enrichment Score (NES) | 1.7129943 |
| Nominal p-value | 0.0051903115 |
| FDR q-value | 0.05164467 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 15 | 1.102 | 0.1482 | Yes |
| 2 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 77 | 0.697 | 0.2381 | Yes |
| 3 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 203 | 0.484 | 0.2944 | Yes |
| 4 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 329 | 0.374 | 0.3356 | Yes |
| 5 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 347 | 0.366 | 0.3840 | Yes |
| 6 | HK1 | HK1 Entrez, Source | hexokinase 1 | 385 | 0.345 | 0.4280 | Yes |
| 7 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 401 | 0.337 | 0.4725 | Yes |
| 8 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 411 | 0.331 | 0.5167 | Yes |
| 9 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.5456 | Yes |
| 10 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 1026 | 0.179 | 0.5324 | No |
| 11 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 1179 | 0.163 | 0.5430 | No |
| 12 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.5434 | No |
| 13 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 1889 | 0.112 | 0.5240 | No |
| 14 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 2152 | 0.101 | 0.5180 | No |
| 15 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 2165 | 0.101 | 0.5308 | No |
| 16 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 2249 | 0.097 | 0.5378 | No |
| 17 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.5273 | No |
| 18 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 2893 | 0.074 | 0.5112 | No |
| 19 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 3358 | 0.061 | 0.4846 | No |
| 20 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 3477 | 0.058 | 0.4837 | No |
| 21 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 3755 | 0.051 | 0.4697 | No |
| 22 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 4179 | 0.040 | 0.4434 | No |
| 23 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 4375 | 0.036 | 0.4336 | No |
| 24 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 4448 | 0.035 | 0.4329 | No |
| 25 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 4624 | 0.032 | 0.4240 | No |
| 26 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 5039 | 0.023 | 0.3961 | No |
| 27 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 5889 | 0.007 | 0.3332 | No |
| 28 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 6088 | 0.003 | 0.3188 | No |
| 29 | HK2 | HK2 Entrez, Source | hexokinase 2 | 6340 | -0.001 | 0.3000 | No |
| 30 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 6466 | -0.003 | 0.2910 | No |
| 31 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6589 | -0.005 | 0.2825 | No |
| 32 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 7034 | -0.013 | 0.2509 | No |
| 33 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 7619 | -0.024 | 0.2102 | No |
| 34 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 8051 | -0.032 | 0.1822 | No |
| 35 | GALM | GALM Entrez, Source | galactose mutarotase (aldose 1-epimerase) | 8209 | -0.035 | 0.1752 | No |
| 36 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 8947 | -0.051 | 0.1266 | No |
| 37 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 9934 | -0.075 | 0.0626 | No |
| 38 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 10001 | -0.077 | 0.0680 | No |
| 39 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 10093 | -0.079 | 0.0719 | No |
| 40 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 10232 | -0.083 | 0.0727 | No |
| 41 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 11040 | -0.109 | 0.0268 | No |
| 42 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 11125 | -0.113 | 0.0359 | No |
| 43 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 11369 | -0.123 | 0.0343 | No |
| 44 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 12067 | -0.162 | 0.0038 | No |
| 45 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 12194 | -0.171 | 0.0175 | No |
| 46 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 12501 | -0.200 | 0.0215 | No |
| 47 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 13052 | -0.307 | 0.0218 | No |
