Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00252_ALANINE_AND_ASPARTATE_METABOLISM |
| Enrichment Score (ES) | 0.61902314 |
| Normalized Enrichment Score (NES) | 1.7090704 |
| Nominal p-value | 0.018484289 |
| FDR q-value | 0.052593336 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.1666 | Yes |
| 2 | AGXT | AGXT Entrez, Source | alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) | 212 | 0.475 | 0.2739 | Yes |
| 3 | PC | PC Entrez, Source | pyruvate carboxylase | 322 | 0.380 | 0.3598 | Yes |
| 4 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 411 | 0.331 | 0.4349 | Yes |
| 5 | AGXT2 | AGXT2 Entrez, Source | alanine-glyoxylate aminotransferase 2 | 428 | 0.322 | 0.5134 | Yes |
| 6 | ASS1 | ASS1 Entrez, Source | argininosuccinate synthetase 1 | 556 | 0.268 | 0.5702 | Yes |
| 7 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 1026 | 0.179 | 0.5792 | Yes |
| 8 | ACY3 | ACY3 Entrez, Source | aspartoacylase (aminocyclase) 3 | 1354 | 0.146 | 0.5909 | Yes |
| 9 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 1485 | 0.136 | 0.6148 | Yes |
| 10 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 2090 | 0.104 | 0.5952 | Yes |
| 11 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 2249 | 0.097 | 0.6074 | Yes |
| 12 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 2398 | 0.092 | 0.6190 | Yes |
| 13 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 3755 | 0.051 | 0.5298 | No |
| 14 | ASNS | ASNS Entrez, Source | asparagine synthetase | 5217 | 0.020 | 0.4251 | No |
| 15 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 6088 | 0.003 | 0.3606 | No |
| 16 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 6099 | 0.003 | 0.3607 | No |
| 17 | GPT | GPT Entrez, Source | glutamic-pyruvate transaminase (alanine aminotransferase) | 6620 | -0.006 | 0.3231 | No |
| 18 | ASL | ASL Entrez, Source | argininosuccinate lyase | 6773 | -0.008 | 0.3138 | No |
| 19 | DARS2 | DARS2 Entrez, Source | aspartyl-tRNA synthetase 2 (mitochondrial) | 8067 | -0.033 | 0.2248 | No |
| 20 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.1487 | No |
| 21 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9641 | -0.066 | 0.1374 | No |
| 22 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11204 | -0.116 | 0.0488 | No |
| 23 | NARS | NARS Entrez, Source | asparaginyl-tRNA synthetase | 11247 | -0.118 | 0.0749 | No |
| 24 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 12016 | -0.158 | 0.0564 | No |
| 25 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12234 | -0.174 | 0.0832 | No |
