Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00410_BETA_ALANINE_METABOLISM |
| Enrichment Score (ES) | 0.64837825 |
| Normalized Enrichment Score (NES) | 1.7043742 |
| Nominal p-value | 0.015444015 |
| FDR q-value | 0.054002922 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 112 | 0.632 | 0.1436 | Yes |
| 2 | UPB1 | UPB1 Entrez, Source | ureidopropionase, beta | 265 | 0.427 | 0.2350 | Yes |
| 3 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 287 | 0.410 | 0.3321 | Yes |
| 4 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 346 | 0.367 | 0.4161 | Yes |
| 5 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 375 | 0.349 | 0.4980 | Yes |
| 6 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.5533 | Yes |
| 7 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 817 | 0.210 | 0.5821 | Yes |
| 8 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 1179 | 0.163 | 0.5942 | Yes |
| 9 | CNDP1 | CNDP1 Entrez, Source | carnosine dipeptidase 1 (metallopeptidase M20 family) | 1188 | 0.162 | 0.6326 | Yes |
| 10 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.6484 | Yes |
| 11 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2173 | 0.101 | 0.6167 | No |
| 12 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 2398 | 0.092 | 0.6220 | No |
| 13 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.6318 | No |
| 14 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 2893 | 0.074 | 0.6236 | No |
| 15 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 3774 | 0.051 | 0.5697 | No |
| 16 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 3794 | 0.050 | 0.5803 | No |
| 17 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 4375 | 0.036 | 0.5455 | No |
| 18 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 5594 | 0.013 | 0.4572 | No |
| 19 | HIBCH | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 8146 | -0.034 | 0.2739 | No |
| 20 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.2034 | No |
| 21 | SRM | SRM Entrez, Source | spermidine synthase | 10934 | -0.106 | 0.1040 | No |
| 22 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11204 | -0.116 | 0.1118 | No |
| 23 | SMS | SMS Entrez, Source | spermine synthase | 12527 | -0.202 | 0.0612 | No |
