Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HSA00790_FOLATE_BIOSYNTHESIS |
| Enrichment Score (ES) | -0.5460311 |
| Normalized Enrichment Score (NES) | -1.4692184 |
| Nominal p-value | 0.045833334 |
| FDR q-value | 0.24682938 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 1478 | 0.137 | -0.0531 | No |
| 2 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 1801 | 0.117 | -0.0278 | No |
| 3 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 2681 | 0.081 | -0.0596 | No |
| 4 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 7441 | -0.021 | -0.4081 | No |
| 5 | ALPI | ALPI Entrez, Source | alkaline phosphatase, intestinal | 7566 | -0.023 | -0.4077 | No |
| 6 | ALPL | ALPL Entrez, Source | alkaline phosphatase, liver/bone/kidney | 8125 | -0.034 | -0.4353 | No |
| 7 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 9602 | -0.065 | -0.5184 | Yes |
| 8 | DDX47 | DDX47 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 9773 | -0.070 | -0.5016 | Yes |
| 9 | DDX50 | DDX50 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 10290 | -0.084 | -0.5048 | Yes |
| 10 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 10351 | -0.086 | -0.4730 | Yes |
| 11 | DDX52 | DDX52 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 11297 | -0.120 | -0.4931 | Yes |
| 12 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 11685 | -0.137 | -0.4640 | Yes |
| 13 | NUDT5 | NUDT5 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 5 | 11827 | -0.146 | -0.4127 | Yes |
| 14 | DDX18 | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 12109 | -0.165 | -0.3639 | Yes |
| 15 | EP400 | EP400 Entrez, Source | E1A binding protein p400 | 12246 | -0.175 | -0.3000 | Yes |
| 16 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12298 | -0.179 | -0.2280 | Yes |
| 17 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12617 | -0.213 | -0.1616 | Yes |
| 18 | DDX56 | DDX56 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 | 12725 | -0.229 | -0.0730 | Yes |
| 19 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12968 | -0.282 | 0.0281 | Yes |
