Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA01430_CELL_COMMUNICATION |
| Enrichment Score (ES) | 0.7362973 |
| Normalized Enrichment Score (NES) | 2.2902348 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.1460313E-4 |
| FWER p-Value | 0.0010 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 7 | 1.391 | 0.1125 | Yes |
| 2 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12 | 1.254 | 0.2142 | Yes |
| 3 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 23 | 1.021 | 0.2965 | Yes |
| 4 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 43 | 0.843 | 0.3636 | Yes |
| 5 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 61 | 0.759 | 0.4241 | Yes |
| 6 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 89 | 0.680 | 0.4773 | Yes |
| 7 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 171 | 0.530 | 0.5143 | Yes |
| 8 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 210 | 0.476 | 0.5502 | Yes |
| 9 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 266 | 0.426 | 0.5807 | Yes |
| 10 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 316 | 0.387 | 0.6085 | Yes |
| 11 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 368 | 0.352 | 0.6332 | Yes |
| 12 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 525 | 0.277 | 0.6440 | Yes |
| 13 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 530 | 0.275 | 0.6661 | Yes |
| 14 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 579 | 0.262 | 0.6837 | Yes |
| 15 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 590 | 0.260 | 0.7041 | Yes |
| 16 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 628 | 0.250 | 0.7216 | Yes |
| 17 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 690 | 0.237 | 0.7363 | Yes |
| 18 | KRT20 | KRT20 Entrez, Source | keratin 20 | 1224 | 0.159 | 0.7091 | No |
| 19 | FN1 | FN1 Entrez, Source | fibronectin 1 | 1246 | 0.156 | 0.7203 | No |
| 20 | KRT25 | KRT25 Entrez, Source | keratin 25 | 1595 | 0.128 | 0.7045 | No |
| 21 | VTN | VTN Entrez, Source | vitronectin | 1776 | 0.118 | 0.7006 | No |
| 22 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2345 | 0.094 | 0.6655 | No |
| 23 | VWF | VWF Entrez, Source | von Willebrand factor | 2400 | 0.092 | 0.6689 | No |
| 24 | NES | NES Entrez, Source | nestin | 2870 | 0.075 | 0.6397 | No |
| 25 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2981 | 0.072 | 0.6372 | No |
| 26 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 3222 | 0.065 | 0.6245 | No |
| 27 | DES | DES Entrez, Source | desmin | 3260 | 0.064 | 0.6269 | No |
| 28 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 3320 | 0.062 | 0.6275 | No |
| 29 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 3344 | 0.061 | 0.6307 | No |
| 30 | RELN | RELN Entrez, Source | reelin | 4416 | 0.035 | 0.5531 | No |
| 31 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 4738 | 0.029 | 0.5313 | No |
| 32 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 4849 | 0.027 | 0.5252 | No |
| 33 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 5170 | 0.021 | 0.5029 | No |
| 34 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 5689 | 0.011 | 0.4648 | No |
| 35 | ACTB | ACTB Entrez, Source | actin, beta | 5788 | 0.009 | 0.4582 | No |
| 36 | GJB4 | GJB4 Entrez, Source | gap junction protein, beta 4 (connexin 30.3) | 6443 | -0.002 | 0.4092 | No |
| 37 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 7051 | -0.013 | 0.3646 | No |
| 38 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 7541 | -0.022 | 0.3296 | No |
| 39 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 7650 | -0.025 | 0.3235 | No |
| 40 | CHAD | CHAD Entrez, Source | chondroadherin | 7677 | -0.025 | 0.3236 | No |
| 41 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 8979 | -0.051 | 0.2299 | No |
| 42 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 9154 | -0.055 | 0.2213 | No |
| 43 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 9402 | -0.061 | 0.2076 | No |
| 44 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 9434 | -0.061 | 0.2103 | No |
| 45 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10524 | -0.091 | 0.1357 | No |
| 46 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 10977 | -0.107 | 0.1105 | No |
| 47 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 11366 | -0.123 | 0.0913 | No |
| 48 | LMNA | LMNA Entrez, Source | lamin A/C | 12500 | -0.199 | 0.0223 | No |
| 49 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13259 | -0.504 | 0.0062 | No |
