Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetHUMAN_MITODB_6_2002
Enrichment Score (ES)0.43324775
Normalized Enrichment Score (NES)1.7310896
Nominal p-value0.0
FDR q-value0.045505527
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: HUMAN_MITODB_6_2002   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4131.1950.0349Yes
2COX6A2COX6A2
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 2350.8900.0601Yes
3GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)760.6970.0780Yes
4CPT1ACPT1A
Entrez,  Source
carnitine palmitoyltransferase 1A (liver)840.6860.0981Yes
5OTCOTC
Entrez,  Source
ornithine carbamoyltransferase1150.6250.1146Yes
6CPS1CPS1
Entrez,  Source
carbamoyl-phosphate synthetase 1, mitochondrial1300.6020.1316Yes
7BCL2A1BCL2A1
Entrez,  Source
BCL2-related protein A11470.5680.1475Yes
8HMGCS2HMGCS2
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)1730.5250.1613Yes
9CA5ACA5A
Entrez,  Source
carbonic anhydrase VA, mitochondrial1990.4870.1741Yes
10AGXTAGXT
Entrez,  Source
alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase)2120.4750.1874Yes
11BCKDHABCKDHA
Entrez,  Source
branched chain keto acid dehydrogenase E1, alpha polypeptide2580.4310.1970Yes
12CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide2640.4270.2094Yes
13PDK4PDK4
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 42850.4100.2202Yes
14CYP27A1CYP27A1
Entrez,  Source
cytochrome P450, family 27, subfamily A, polypeptide 12970.4030.2315Yes
15DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)3020.3990.2432Yes
16PCPC
Entrez,  Source
pyruvate carboxylase3220.3800.2532Yes
17POPDC2POPDC2
Entrez,  Source
popeye domain containing 23270.3740.2641Yes
18SLC25A15SLC25A15
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 153380.3710.2745Yes
19ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial3460.3670.2850Yes
20GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase3790.3480.2930Yes
21HK1HK1
Entrez,  Source
hexokinase 13850.3450.3030Yes
22TATTAT
Entrez,  Source
tyrosine aminotransferase3900.3410.3130Yes
23DLATDLAT
Entrez,  Source
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)4110.3310.3214Yes
24CPT2CPT2
Entrez,  Source
carnitine palmitoyltransferase II4190.3260.3307Yes
25UCP2UCP2
Entrez,  Source
uncoupling protein 2 (mitochondrial, proton carrier)4430.3130.3383Yes
26DECR1DECR1
Entrez,  Source
2,4-dienoyl CoA reductase 1, mitochondrial4860.2910.3439Yes
27HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 15010.2860.3514Yes
28DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E25410.2720.3566Yes
29ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)6240.2510.3579Yes
30IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase8000.2130.3509Yes
31NGFRAP1NGFRAP1
Entrez,  Source
nerve growth factor receptor (TNFRSF16) associated protein 18300.2080.3549Yes
32IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha8430.2060.3602Yes
33MIPEPMIPEP
Entrez,  Source
mitochondrial intermediate peptidase8670.2000.3645Yes
34BCKDKBCKDK
Entrez,  Source
branched chain ketoacid dehydrogenase kinase8690.2000.3704Yes
35SCP2SCP2
Entrez,  Source
sterol carrier protein 28900.1970.3748Yes
36BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)9060.1950.3795Yes
37ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial9400.1890.3827Yes
38ETFDHETFDH
Entrez,  Source
electron-transferring-flavoprotein dehydrogenase9620.1870.3867Yes
39POLGPOLG
Entrez,  Source
polymerase (DNA directed), gamma9850.1850.3906Yes
40SLC25A20SLC25A20
Entrez,  Source
solute carrier family 25 (carnitine/acylcarnitine translocase), member 209900.1830.3958Yes
41SDSSDS
Entrez,  Source
serine dehydratase10070.1820.4000Yes
42ABCB8ABCB8
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 810190.1800.4046Yes
43DNASE2DNASE2
Entrez,  Source
deoxyribonuclease II, lysosomal10960.1710.4040Yes
44IDH3GIDH3G
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) gamma11350.1670.4061Yes
45SARDHSARDH
Entrez,  Source
sarcosine dehydrogenase11500.1650.4100Yes
46PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide11520.1650.4148Yes
47SLC25A21SLC25A21
Entrez,  Source
solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 2111930.1620.4166Yes
48BAK1BAK1
Entrez,  Source
BCL2-antagonist/killer 114770.1370.3991Yes
49ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)14820.1360.4029Yes
50CRATCRAT
Entrez,  Source
carnitine acetyltransferase14850.1360.4069Yes
51BADBAD
Entrez,  Source
BCL2-antagonist of cell death15300.1330.4075Yes
52MAOBMAOB
Entrez,  Source
monoamine oxidase B15310.1330.4115Yes
53PRDX3PRDX3
Entrez,  Source
peroxiredoxin 315340.1320.4153Yes
54ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain15440.1320.4186Yes
55NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)15540.1310.4218Yes
56TIMM8BTIMM8B
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog B (yeast)15830.1290.4236Yes
57ARG2ARG2
Entrez,  Source
arginase, type II16060.1280.4258Yes
58COQ7COQ7
Entrez,  Source
coenzyme Q7 homolog, ubiquinone (yeast)16320.1260.4276Yes
59ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain17150.1220.4250Yes
60ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain17200.1220.4284Yes
61COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb17470.1190.4300Yes
62ATP5EATP5E
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit17730.1180.4317Yes
63AK3AK3
Entrez,  Source
adenylate kinase 318120.1160.4322Yes
64SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)18450.1150.4332Yes
65UQCRBUQCRB
Entrez,  Source
ubiquinol-cytochrome c reductase binding protein19050.1110.4321No
66TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)19690.1090.4306No
67ATP7BATP7B
Entrez,  Source
ATPase, Cu++ transporting, beta polypeptide19990.1080.4316No
68MAOAMAOA
Entrez,  Source
monoamine oxidase A21590.1010.4225No
69HADHAHADHA
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit21730.1010.4245No
70AMTAMT
Entrez,  Source
aminomethyltransferase22210.0980.4239No
71PDHA1PDHA1
Entrez,  Source
pyruvate dehydrogenase (lipoamide) alpha 122490.0970.4247No
72TXN2TXN2
Entrez,  Source
thioredoxin 223700.0930.4184No
73ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase23980.0920.4191No
74NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa24280.0900.4196No
75MCCC1MCCC1
Entrez,  Source
methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)24540.0900.4203No
76UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein24940.0880.4200No
77ODC1ODC1
Entrez,  Source
ornithine decarboxylase 125070.0880.4217No
78ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)25440.0860.4216No
79ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide25640.0850.4227No
80NFS1NFS1
Entrez,  Source
NFS1 nitrogen fixation 1 (S. cerevisiae)25700.0850.4248No
81ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)25930.0840.4257No
82GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)27130.0800.4190No
83ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F627380.0790.4195No
84COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc27390.0790.4219No
85SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein28180.0770.4182No
86MDH2MDH2
Entrez,  Source
malate dehydrogenase 2, NAD (mitochondrial)28600.0750.4173No
87NDUFB4NDUFB4
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa29000.0740.4166No
88ACADVLACADVL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, very long chain30020.0710.4110No
89COX7A2COX7A2
Entrez,  Source
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)31230.0680.4039No
90APAF1APAF1
Entrez,  Source
apoptotic peptidase activating factor31640.0670.4028No
91ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)32090.0650.4014No
92CYCSCYCS
Entrez,  Source
cytochrome c, somatic32560.0640.3999No
93UROSUROS
Entrez,  Source
uroporphyrinogen III synthase (congenital erythropoietic porphyria)33050.0630.3981No
94SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa33110.0620.3996No
95COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 133350.0620.3997No
96DNM1LDNM1L
Entrez,  Source
dynamin 1-like34990.0580.3889No
97ACP6ACP6
Entrez,  Source
acid phosphatase 6, lysophosphatidic35210.0570.3890No
98MPSTMPST
Entrez,  Source
mercaptopyruvate sulfurtransferase36210.0540.3831No
99SUCLG1SUCLG1
Entrez,  Source
succinate-CoA ligase, GDP-forming, alpha subunit37540.0510.3746No
100PDHBPDHB
Entrez,  Source
pyruvate dehydrogenase (lipoamide) beta37550.0510.3761No
101CA5BCA5B
Entrez,  Source
carbonic anhydrase VB, mitochondrial37870.0500.3752No
102ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain37940.0500.3763No
103NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)37960.0500.3777No
104SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 138010.0500.3789No
105HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 138720.0480.3750No
106DLSTDLST
Entrez,  Source
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)39050.0470.3740No
107SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 1039660.0450.3708No
108ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)40110.0440.3687No
109BCL2BCL2
Entrez,  Source
B-cell CLL/lymphoma 241870.0400.3566No
110MRPS18AMRPS18A
Entrez,  Source
mitochondrial ribosomal protein S18A41930.0400.3574No
111MTCH1MTCH1
Entrez,  Source
mitochondrial carrier homolog 1 (C. elegans)42130.0390.3571No
112MRPL34MRPL34
Entrez,  Source
mitochondrial ribosomal protein L3442390.0390.3564No
113SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)42570.0380.3562No
114DIABLODIABLO
Entrez,  Source
diablo homolog (Drosophila)42760.0380.3560No
115GLUD1GLUD1
Entrez,  Source
glutamate dehydrogenase 142970.0380.3556No
116SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 144690.0350.3436No
117CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 146490.0310.3308No
118COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va46720.0310.3301No
119NDUFC2NDUFC2
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa47430.0290.3256No
120NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47670.0290.3247No
121SLC25A3SLC25A3
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 348060.0280.3226No
122ATP5F1ATP5F1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B148250.0280.3221No
123NDUFA9NDUFA9
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa48530.0270.3208No
124ETFBETFB
Entrez,  Source
electron-transfer-flavoprotein, beta polypeptide49560.0250.3138No
125PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)51230.0220.3017No
126CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)52650.0190.2916No
127COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb54090.0170.2811No
128FIBPFIBP
Entrez,  Source
fibroblast growth factor (acidic) intracellular binding protein54660.0160.2773No
129UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II54870.0150.2762No
130ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)56040.0130.2678No
131COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 156100.0130.2678No
132ATP5C1ATP5C1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 157170.0110.2600No
133BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like57290.0100.2594No
134IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)57610.0100.2574No
135MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S757870.0090.2557No
136ATP5IATP5I
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E57930.0090.2556No
137ATP5DATP5D
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit58160.0090.2542No
138UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I59270.0070.2460No
139MFN2MFN2
Entrez,  Source
mitofusin 259520.0060.2444No
140NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa60090.0050.2402No
141UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 160100.0050.2404No
142SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 560800.0040.2352No
143BCAT2BCAT2
Entrez,  Source
branched chain aminotransferase 2, mitochondrial60860.0040.2349No
144DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase60880.0030.2350No
145AKAP1AKAP1
Entrez,  Source
A kinase (PRKA) anchor protein 160920.0030.2348No
146NDUFA8NDUFA8
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa6312-0.0000.2181No
147PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)6391-0.0020.2122No
148HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)6540-0.0040.2010No
149GPTGPT
Entrez,  Source
glutamic-pyruvate transaminase (alanine aminotransferase)6620-0.0060.1952No
150MRPL13MRPL13
Entrez,  Source
mitochondrial ribosomal protein L136839-0.0090.1788No
151CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase6929-0.0110.1723No
152HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)7083-0.0140.1611No
153OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase7089-0.0140.1611No
154TRAP1TRAP1
Entrez,  Source
TNF receptor-associated protein 17108-0.0140.1601No
155ATP5HATP5H
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d7126-0.0140.1593No
156CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 17135-0.0140.1591No
157FDXRFDXR
Entrez,  Source
ferredoxin reductase7183-0.0150.1560No
158DAP3DAP3
Entrez,  Source
death associated protein 37418-0.0200.1387No
159SLC25A11SLC25A11
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 117432-0.0200.1383No
160GRID2GRID2
Entrez,  Source
glutamate receptor, ionotropic, delta 27487-0.0210.1348No
161TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)7491-0.0210.1353No
162SLC1A3SLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 37511-0.0220.1345No
163MRPL2MRPL2
Entrez,  Source
mitochondrial ribosomal protein L27520-0.0220.1345No
164BCL2L1BCL2L1
Entrez,  Source
BCL2-like 17544-0.0220.1334No
165GALR3GALR3
Entrez,  Source
galanin receptor 37605-0.0240.1295No
166MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase7607-0.0240.1302No
167MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L127694-0.0250.1244No
168MRPL11MRPL11
Entrez,  Source
mitochondrial ribosomal protein L117805-0.0270.1168No
169SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)7827-0.0280.1160No
170MRPL49MRPL49
Entrez,  Source
mitochondrial ribosomal protein L497943-0.0300.1081No
171NDUFS7NDUFS7
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)7963-0.0310.1076No
172TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)7975-0.0310.1077No
173HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit7978-0.0310.1085No
174UCP3UCP3
Entrez,  Source
uncoupling protein 3 (mitochondrial, proton carrier)8132-0.0340.0978No
175VDAC3VDAC3
Entrez,  Source
voltage-dependent anion channel 38170-0.0350.0960No
176LYPLA2LYPLA2
Entrez,  Source
lysophospholipase II8179-0.0350.0964No
177COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)8234-0.0360.0934No
178NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)8263-0.0370.0924No
179VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 28408-0.0400.0826No
180TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)8638-0.0440.0664No
181MRPL17MRPL17
Entrez,  Source
mitochondrial ribosomal protein L178647-0.0440.0671No
182STARSTAR
Entrez,  Source
steroidogenic acute regulator8839-0.0490.0540No
183IDH3BIDH3B
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) beta8861-0.0490.0538No
184MRPL16MRPL16
Entrez,  Source
mitochondrial ribosomal protein L168903-0.0500.0522No
185PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta9068-0.0530.0413No
186GLSGLS
Entrez,  Source
glutaminase9073-0.0530.0426No
187TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)9181-0.0560.0361No
188MRPL44MRPL44
Entrez,  Source
mitochondrial ribosomal protein L449194-0.0560.0368No
189HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)9296-0.0580.0309No
190TOMM22TOMM22
Entrez,  Source
translocase of outer mitochondrial membrane 22 homolog (yeast)9313-0.0580.0314No
191ABCB6ABCB6
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 69334-0.0590.0317No
192BLVRABLVRA
Entrez,  Source
biliverdin reductase A9379-0.0600.0301No
193RPL3RPL3
Entrez,  Source
ribosomal protein L39460-0.0620.0258No
194RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A9486-0.0630.0258No
195SUPV3L1SUPV3L1
Entrez,  Source
suppressor of var1, 3-like 1 (S. cerevisiae)9489-0.0630.0275No
196MUTYHMUTYH
Entrez,  Source
mutY homolog (E. coli)9606-0.0650.0207No
197GOT2GOT2
Entrez,  Source
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)9641-0.0660.0200No
198SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 19677-0.0670.0194No
199CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)9683-0.0670.0210No
200TFB1MTFB1M
Entrez,  Source
transcription factor B1, mitochondrial9706-0.0680.0214No
201NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)9848-0.0720.0128No
202BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 39855-0.0730.0145No
203ENDOGENDOG
Entrez,  Source
endonuclease G9860-0.0730.0164No
204UCP1UCP1
Entrez,  Source
uncoupling protein 1 (mitochondrial, proton carrier)9902-0.0740.0155No
205ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 19995-0.0760.0108No
206TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)10050-0.0780.0090No
207CLPXCLPX
Entrez,  Source
ClpX caseinolytic peptidase X homolog (E. coli)10353-0.086-0.0115No
208AK2AK2
Entrez,  Source
adenylate kinase 210466-0.089-0.0174No
209BAXBAX
Entrez,  Source
BCL2-associated X protein10485-0.090-0.0161No
210TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)10517-0.091-0.0157No
211TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 210598-0.093-0.0190No
212PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit10702-0.097-0.0239No
213TIMM13TIMM13
Entrez,  Source
translocase of inner mitochondrial membrane 13 homolog (yeast)10719-0.098-0.0222No
214CYP11B1CYP11B1
Entrez,  Source
cytochrome P450, family 11, subfamily B, polypeptide 110757-0.099-0.0221No
215MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1910771-0.100-0.0201No
216GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)10782-0.100-0.0178No
217MTERFMTERF
Entrez,  Source
mitochondrial transcription termination factor10821-0.102-0.0177No
218OPA1OPA1
Entrez,  Source
optic atrophy 1 (autosomal dominant)10860-0.103-0.0175No
219TIMM44TIMM44
Entrez,  Source
translocase of inner mitochondrial membrane 44 homolog (yeast)10966-0.107-0.0223No
220BCL2L11BCL2L11
Entrez,  Source
BCL2-like 11 (apoptosis facilitator)11005-0.108-0.0219No
221BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)11013-0.109-0.0192No
222PDK1PDK1
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 111028-0.109-0.0170No
223DUTDUT
Entrez,  Source
dUTP pyrophosphatase11183-0.116-0.0253No
224MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L4611276-0.119-0.0287No
225RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 111362-0.123-0.0315No
226AFG3L2AFG3L2
Entrez,  Source
AFG3 ATPase family gene 3-like 2 (yeast)11473-0.128-0.0361No
227MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B11505-0.129-0.0345No
228MRPS15MRPS15
Entrez,  Source
mitochondrial ribosomal protein S1511628-0.135-0.0398No
229OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)11781-0.143-0.0471No
230FDX1FDX1
Entrez,  Source
ferredoxin 111784-0.144-0.0429No
231TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)11829-0.146-0.0419No
232SOD2SOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial11883-0.149-0.0415No
233SHMT2SHMT2
Entrez,  Source
serine hydroxymethyltransferase 2 (mitochondrial)11904-0.150-0.0385No
234CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)11907-0.150-0.0341No
235FRAP1FRAP1
Entrez,  Source
FK506 binding protein 12-rapamycin associated protein 111920-0.151-0.0305No
236TFAMTFAM
Entrez,  Source
transcription factor A, mitochondrial11975-0.156-0.0299No
237AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase12034-0.160-0.0295No
238MRPL24MRPL24
Entrez,  Source
mitochondrial ribosomal protein L2412072-0.162-0.0275No
239BIDBID
Entrez,  Source
BH3 interacting domain death agonist12086-0.163-0.0236No
240SURF1SURF1
Entrez,  Source
surfeit 112247-0.175-0.0305No
241MRPL9MRPL9
Entrez,  Source
mitochondrial ribosomal protein L912275-0.177-0.0273No
242MTIF2MTIF2
Entrez,  Source
mitochondrial translational initiation factor 212340-0.183-0.0267No
243DHODHDHODH
Entrez,  Source
dihydroorotate dehydrogenase12530-0.202-0.0350No
244GCATGCAT
Entrez,  Source
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)12561-0.206-0.0311No
245TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)12582-0.208-0.0264No
246PPIDPPID
Entrez,  Source
peptidylprolyl isomerase D (cyclophilin D)12627-0.215-0.0233No
247GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)12638-0.216-0.0176No
248CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)12664-0.219-0.0129No
249CSCS
Entrez,  Source
citrate synthase12671-0.220-0.0067No
250ATP5G2ATP5G2
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)12683-0.222-0.0009No
251ATP5SATP5S
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B)12961-0.279-0.0136No
252GCKGCK
Entrez,  Source
glucokinase (hexokinase 4, maturity onset diabetes of the young 2)13052-0.307-0.0113No
253PRSS15PRSS15
Entrez,  Source
protease, serine, 1513072-0.315-0.0033No
254GSRGSR
Entrez,  Source
glutathione reductase13171-0.3760.0006No
255ATPIF1ATPIF1
Entrez,  Source
ATPase inhibitory factor 113209-0.4130.0102No
Table: GSEA details [plain text format]



Fig 2: HUMAN_MITODB_6_2002   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HUMAN_MITODB_6_2002: Random ES distribution   
Gene set null distribution of ES for HUMAN_MITODB_6_2002