Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HYPOXIA_RCC_UP |
| Enrichment Score (ES) | -0.48691124 |
| Normalized Enrichment Score (NES) | -1.6443594 |
| Nominal p-value | 0.0065645515 |
| FDR q-value | 0.12601995 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD276 | CD276 Entrez, Source | CD276 molecule | 492 | 0.288 | 0.0081 | No |
| 2 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 1409 | 0.142 | -0.0386 | No |
| 3 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 1830 | 0.115 | -0.0522 | No |
| 4 | WDR6 | WDR6 Entrez, Source | WD repeat domain 6 | 2079 | 0.104 | -0.0545 | No |
| 5 | APLP2 | APLP2 Entrez, Source | amyloid beta (A4) precursor-like protein 2 | 2657 | 0.082 | -0.0851 | No |
| 6 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 2671 | 0.081 | -0.0734 | No |
| 7 | DPM2 | DPM2 Entrez, Source | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | 2678 | 0.081 | -0.0612 | No |
| 8 | MRPL41 | MRPL41 Entrez, Source | mitochondrial ribosomal protein L41 | 2849 | 0.076 | -0.0622 | No |
| 9 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 3636 | 0.054 | -0.1129 | No |
| 10 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 3963 | 0.045 | -0.1303 | No |
| 11 | ATP5G3 | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 4011 | 0.044 | -0.1269 | No |
| 12 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 4467 | 0.035 | -0.1558 | No |
| 13 | CTSC | CTSC Entrez, Source | cathepsin C | 4468 | 0.035 | -0.1504 | No |
| 14 | SSU72 | SSU72 Entrez, Source | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 4650 | 0.031 | -0.1591 | No |
| 15 | ARF5 | ARF5 Entrez, Source | ADP-ribosylation factor 5 | 4657 | 0.031 | -0.1548 | No |
| 16 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 5660 | 0.012 | -0.2283 | No |
| 17 | GADD45GIP1 | GADD45GIP1 Entrez, Source | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 5861 | 0.008 | -0.2421 | No |
| 18 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 6839 | -0.009 | -0.3142 | No |
| 19 | PRPF19 | PRPF19 Entrez, Source | PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) | 8971 | -0.051 | -0.4665 | No |
| 20 | RPL37 | RPL37 Entrez, Source | ribosomal protein L37 | 9243 | -0.057 | -0.4780 | Yes |
| 21 | YIPF5 | YIPF5 Entrez, Source | Yip1 domain family, member 5 | 9320 | -0.059 | -0.4746 | Yes |
| 22 | GTF2A2 | GTF2A2 Entrez, Source | general transcription factor IIA, 2, 12kDa | 9356 | -0.059 | -0.4679 | Yes |
| 23 | LRRC48 | LRRC48 Entrez, Source | leucine rich repeat containing 48 | 9381 | -0.060 | -0.4603 | Yes |
| 24 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 9440 | -0.061 | -0.4551 | Yes |
| 25 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9460 | -0.062 | -0.4468 | Yes |
| 26 | CNTN5 | CNTN5 Entrez, Source | contactin 5 | 9509 | -0.063 | -0.4406 | Yes |
| 27 | GNG12 | GNG12 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 12 | 9591 | -0.065 | -0.4365 | Yes |
| 28 | PPM1F | PPM1F Entrez, Source | protein phosphatase 1F (PP2C domain containing) | 9827 | -0.072 | -0.4430 | Yes |
| 29 | RHOT2 | RHOT2 Entrez, Source | ras homolog gene family, member T2 | 9998 | -0.076 | -0.4438 | Yes |
| 30 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10112 | -0.079 | -0.4399 | Yes |
| 31 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 10391 | -0.087 | -0.4472 | Yes |
| 32 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.4368 | Yes |
| 33 | TRSPAP1 | TRSPAP1 Entrez, Source | tRNA selenocysteine associated protein 1 | 10570 | -0.092 | -0.4322 | Yes |
| 34 | HIRIP3 | HIRIP3 Entrez, Source | HIRA interacting protein 3 | 11261 | -0.119 | -0.4656 | Yes |
| 35 | RAB14 | RAB14 Entrez, Source | RAB14, member RAS oncogene family | 11280 | -0.119 | -0.4482 | Yes |
| 36 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 11388 | -0.124 | -0.4369 | Yes |
| 37 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 11399 | -0.125 | -0.4181 | Yes |
| 38 | CAND1 | CAND1 Entrez, Source | cullin-associated and neddylation-dissociated 1 | 11749 | -0.141 | -0.4223 | Yes |
| 39 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 11900 | -0.150 | -0.4101 | Yes |
| 40 | METTL3 | METTL3 Entrez, Source | methyltransferase like 3 | 12152 | -0.168 | -0.4027 | Yes |
| 41 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 12393 | -0.187 | -0.3915 | Yes |
| 42 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 12401 | -0.188 | -0.3626 | Yes |
| 43 | TMEM5 | TMEM5 Entrez, Source | transmembrane protein 5 | 12435 | -0.191 | -0.3351 | Yes |
| 44 | PARL | PARL Entrez, Source | presenilin associated, rhomboid-like | 12467 | -0.195 | -0.3070 | Yes |
| 45 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.2851 | Yes |
| 46 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 12758 | -0.234 | -0.2587 | Yes |
| 47 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 12770 | -0.237 | -0.2225 | Yes |
| 48 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.1862 | Yes |
| 49 | SCARB2 | SCARB2 Entrez, Source | scavenger receptor class B, member 2 | 12952 | -0.277 | -0.1555 | Yes |
| 50 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 12969 | -0.282 | -0.1126 | Yes |
| 51 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 13164 | -0.372 | -0.0690 | Yes |
| 52 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13274 | -0.526 | 0.0051 | Yes |
