Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | HYPOXIA_REG_UP |
| Enrichment Score (ES) | -0.4526459 |
| Normalized Enrichment Score (NES) | -1.3726346 |
| Nominal p-value | 0.08898305 |
| FDR q-value | 0.32597017 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPRC5A | GPRC5A Entrez, Source | G protein-coupled receptor, family C, group 5, member A | 104 | 0.658 | 0.1099 | No |
| 2 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 401 | 0.337 | 0.1480 | No |
| 3 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 956 | 0.188 | 0.1400 | No |
| 4 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.1444 | No |
| 5 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 1441 | 0.140 | 0.1563 | No |
| 6 | PFKFB4 | PFKFB4 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 2371 | 0.093 | 0.1032 | No |
| 7 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 2752 | 0.078 | 0.0887 | No |
| 8 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3202 | 0.066 | 0.0667 | No |
| 9 | PHC2 | PHC2 Entrez, Source | polyhomeotic homolog 2 (Drosophila) | 3972 | 0.045 | 0.0170 | No |
| 10 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 4456 | 0.035 | -0.0130 | No |
| 11 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 5039 | 0.023 | -0.0526 | No |
| 12 | ADORA2B | ADORA2B Entrez, Source | adenosine A2b receptor | 5772 | 0.010 | -0.1059 | No |
| 13 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 8468 | -0.041 | -0.3010 | No |
| 14 | MUC1 | MUC1 Entrez, Source | mucin 1, cell surface associated | 9275 | -0.058 | -0.3512 | No |
| 15 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 9855 | -0.073 | -0.3818 | No |
| 16 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 10260 | -0.083 | -0.3972 | No |
| 17 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 10654 | -0.095 | -0.4096 | No |
| 18 | ADM | ADM Entrez, Source | adrenomedullin | 11063 | -0.110 | -0.4205 | No |
| 19 | PTDSR | PTDSR Entrez, Source | phosphatidylserine receptor | 11443 | -0.127 | -0.4263 | No |
| 20 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 11795 | -0.144 | -0.4269 | Yes |
| 21 | SLC16A3 | SLC16A3 Entrez, Source | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | 12008 | -0.158 | -0.4145 | Yes |
| 22 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 12194 | -0.171 | -0.3978 | Yes |
| 23 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 12217 | -0.173 | -0.3686 | Yes |
| 24 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 12221 | -0.173 | -0.3378 | Yes |
| 25 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | -0.3403 | Yes |
| 26 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 12884 | -0.262 | -0.2940 | Yes |
| 27 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12951 | -0.277 | -0.2494 | Yes |
| 28 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13034 | -0.303 | -0.2013 | Yes |
| 29 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.1477 | Yes |
| 30 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 13207 | -0.413 | -0.0834 | Yes |
| 31 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13269 | -0.522 | 0.0055 | Yes |
