Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | IFN_BETA_UP |
| Enrichment Score (ES) | -0.62829334 |
| Normalized Enrichment Score (NES) | -2.0234897 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0062002703 |
| FWER p-Value | 0.08 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 898 | 0.196 | -0.0355 | No |
| 2 | AP3M2 | AP3M2 Entrez, Source | adaptor-related protein complex 3, mu 2 subunit | 2256 | 0.097 | -0.1217 | No |
| 3 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 2474 | 0.089 | -0.1235 | No |
| 4 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 2628 | 0.083 | -0.1215 | No |
| 5 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 3080 | 0.069 | -0.1441 | No |
| 6 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 3083 | 0.069 | -0.1331 | No |
| 7 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 3329 | 0.062 | -0.1414 | No |
| 8 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 3401 | 0.060 | -0.1369 | No |
| 9 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 3715 | 0.052 | -0.1519 | No |
| 10 | PPP5C | PPP5C Entrez, Source | protein phosphatase 5, catalytic subunit | 4288 | 0.038 | -0.1888 | No |
| 11 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 5081 | 0.023 | -0.2446 | No |
| 12 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 5132 | 0.022 | -0.2449 | No |
| 13 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 5285 | 0.019 | -0.2532 | No |
| 14 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5509 | 0.014 | -0.2676 | No |
| 15 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 6929 | -0.011 | -0.3725 | No |
| 16 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6942 | -0.011 | -0.3715 | No |
| 17 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7229 | -0.017 | -0.3903 | No |
| 18 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 7528 | -0.022 | -0.4091 | No |
| 19 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 7978 | -0.031 | -0.4378 | No |
| 20 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 8711 | -0.046 | -0.4854 | No |
| 21 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 10074 | -0.079 | -0.5750 | No |
| 22 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 10451 | -0.089 | -0.5887 | No |
| 23 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 10574 | -0.093 | -0.5828 | No |
| 24 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | -0.6095 | Yes |
| 25 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 11364 | -0.123 | -0.6031 | Yes |
| 26 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 11435 | -0.126 | -0.5878 | Yes |
| 27 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11603 | -0.133 | -0.5786 | Yes |
| 28 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 11843 | -0.147 | -0.5726 | Yes |
| 29 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12097 | -0.164 | -0.5648 | Yes |
| 30 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 12473 | -0.196 | -0.5611 | Yes |
| 31 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 12573 | -0.208 | -0.5346 | Yes |
| 32 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 12750 | -0.233 | -0.5098 | Yes |
| 33 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 12770 | -0.237 | -0.4727 | Yes |
| 34 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12920 | -0.270 | -0.4397 | Yes |
| 35 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 12999 | -0.292 | -0.3980 | Yes |
| 36 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 13047 | -0.306 | -0.3516 | Yes |
| 37 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 13115 | -0.335 | -0.3019 | Yes |
| 38 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 13228 | -0.440 | -0.2386 | Yes |
| 39 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 13294 | -0.577 | -0.1493 | Yes |
| 40 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 13331 | -0.937 | 0.0008 | Yes |
