Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetIRITANI_ADPROX_VASC
Enrichment Score (ES)0.571636
Normalized Enrichment Score (NES)2.0380063
Nominal p-value0.0
FDR q-value0.003022846
FWER p-Value0.073
Table: GSEA Results Summary



Fig 1: Enrichment plot: IRITANI_ADPROX_VASC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 2121.2540.0731Yes
2LDHBLDHB
Entrez,  Source
lactate dehydrogenase B151.1020.1380Yes
3LAMC2LAMC2
Entrez,  Source
laminin, gamma 2231.0210.1977Yes
4CLDN7CLDN7
Entrez,  Source
claudin 7360.8880.2492Yes
5TAGLNTAGLN
Entrez,  Source
transgelin400.8740.3005Yes
6PROCRPROCR
Entrez,  Source
protein C receptor, endothelial (EPCR)590.7630.3442Yes
7BGNBGN
Entrez,  Source
biglycan2410.4500.3571Yes
8RGS10RGS10
Entrez,  Source
regulator of G-protein signalling 102470.4430.3828Yes
9PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)2900.4080.4037Yes
10LAMA5LAMA5
Entrez,  Source
laminin, alpha 53680.3520.4187Yes
11CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 24050.3360.4358Yes
12CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)4740.2940.4480Yes
13ANXA3ANXA3
Entrez,  Source
annexin A34840.2910.4645Yes
14PKIAPKIA
Entrez,  Source
protein kinase (cAMP-dependent, catalytic) inhibitor alpha5880.2600.4721Yes
15RGS4RGS4
Entrez,  Source
regulator of G-protein signalling 46390.2470.4829Yes
16IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 37460.2280.4883Yes
17AGRINAGRIN
Entrez,  Source
agrin8010.2130.4968Yes
18ECE1ECE1
Entrez,  Source
endothelin converting enzyme 18140.2110.5084Yes
19CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein8180.2100.5206Yes
20FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)8350.2070.5316Yes
21IER3IER3
Entrez,  Source
immediate early response 39080.1950.5376Yes
22ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide9730.1860.5438Yes
23LPXNLPXN
Entrez,  Source
leupaxin9790.1850.5543Yes
24BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 110310.1780.5610Yes
25UPP1UPP1
Entrez,  Source
uridine phosphorylase 110700.1740.5684Yes
26EIF2B2EIF2B2
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa11560.1640.5716Yes
27VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C14100.1420.5609No
28ANXA6ANXA6
Entrez,  Source
annexin A617140.1220.5452No
29TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia17290.1210.5513No
30ENO2ENO2
Entrez,  Source
enolase 2 (gamma, neuronal)18890.1120.5459No
31NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 220480.1060.5402No
32RHOBRHOB
Entrez,  Source
ras homolog gene family, member B20720.1050.5447No
33ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta25410.0860.5144No
34ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)25440.0860.5193No
35SLC38A6SLC38A6
Entrez,  Source
solute carrier family 38, member 627490.0790.5086No
36ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 228730.0750.5037No
37CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like28910.0740.5068No
38MAPKAPK3MAPKAPK3
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 330690.0690.4975No
39AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase30860.0690.5004No
40MMP14MMP14
Entrez,  Source
matrix metallopeptidase 14 (membrane-inserted)31760.0660.4976No
41LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 233240.0620.4901No
42BMP6BMP6
Entrez,  Source
bone morphogenetic protein 633480.0610.4920No
43EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 133780.0610.4934No
44BTG2BTG2
Entrez,  Source
BTG family, member 237590.0510.4677No
45CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 437670.0510.4702No
46PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)37850.0500.4719No
47SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)37900.0500.4745No
48SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 138010.0500.4767No
49TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa41250.0420.4548No
50PFKMPFKM
Entrez,  Source
phosphofructokinase, muscle41790.0400.4532No
51CHST1CHST1
Entrez,  Source
carbohydrate (keratan sulfate Gal-6) sulfotransferase 142270.0390.4519No
52LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 242800.0380.4502No
53CTSCCTSC
Entrez,  Source
cathepsin C44680.0350.4382No
54SELPSELP
Entrez,  Source
selectin P (granule membrane protein 140kDa, antigen CD62)47410.0290.4193No
55ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta48270.0270.4145No
56LPHN2LPHN2
Entrez,  Source
latrophilin 249820.0240.4044No
57SRPXSRPX
Entrez,  Source
sushi-repeat-containing protein, X-linked51530.0210.3928No
58PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule52640.0190.3856No
59IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)52850.0190.3852No
60NISCHNISCH
Entrez,  Source
nischarin53320.0180.3828No
61CLUCLU
Entrez,  Source
clusterin54430.0160.3754No
62MVPMVP
Entrez,  Source
major vault protein60490.0040.3300No
63CDH2CDH2
Entrez,  Source
cadherin 2, type 1, N-cadherin (neuronal)61220.0030.3247No
64TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 262450.0010.3156No
65PFN2PFN2
Entrez,  Source
profilin 262810.0000.3129No
66TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)6293-0.0000.3121No
67RAC2RAC2
Entrez,  Source
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)6381-0.0010.3056No
68CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)6484-0.0030.2981No
69ICAM1ICAM1
Entrez,  Source
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor6591-0.0050.2904No
70JUNJUN
Entrez,  Source
jun oncogene6649-0.0060.2865No
71MT1AMT1A
Entrez,  Source
metallothionein 1A (functional)6765-0.0080.2783No
72PDLIM4PDLIM4
Entrez,  Source
PDZ and LIM domain 46797-0.0090.2765No
73ITGB5ITGB5
Entrez,  Source
integrin, beta 57282-0.0180.2410No
74CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)7897-0.0290.1963No
75LYL1LYL1
Entrez,  Source
lymphoblastic leukemia derived sequence 17941-0.0300.1948No
76TFECTFEC
Entrez,  Source
transcription factor EC8607-0.0440.1472No
77MT3MT3
Entrez,  Source
metallothionein 3 (growth inhibitory factor (neurotrophic))8612-0.0440.1495No
78CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)8685-0.0450.1467No
79PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein8718-0.0460.1470No
80IL4RIL4R
Entrez,  Source
interleukin 4 receptor9312-0.0580.1057No
81ARL6IP5ARL6IP5
Entrez,  Source
ADP-ribosylation-like factor 6 interacting protein 59523-0.0630.0935No
82MLLT11MLLT11
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1110269-0.0830.0422No
83FAPFAP
Entrez,  Source
fibroblast activation protein, alpha10470-0.0890.0324No
84TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 210598-0.0930.0283No
85SELESELE
Entrez,  Source
selectin E (endothelial adhesion molecule 1)10650-0.0950.0301No
86ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)10917-0.1060.0162No
87TGM2TGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)10955-0.1070.0197No
88SORDSORD
Entrez,  Source
sorbitol dehydrogenase11093-0.1120.0160No
89SLC6A8SLC6A8
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, creatine), member 811242-0.1180.0118No
90FHL2FHL2
Entrez,  Source
four and a half LIM domains 211359-0.1230.0103No
91CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)11461-0.1270.0101No
92SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 711894-0.150-0.0136No
93PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase12137-0.167-0.0220No
94UCHL1UCHL1
Entrez,  Source
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)12209-0.172-0.0173No
95GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha12556-0.205-0.0313No
96NRCAMNRCAM
Entrez,  Source
neuronal cell adhesion molecule12687-0.222-0.0280No
97GBP2GBP2
Entrez,  Source
guanylate binding protein 2, interferon-inducible12797-0.241-0.0220No
98NMT2NMT2
Entrez,  Source
N-myristoyltransferase 212888-0.263-0.0133No
99SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 112951-0.277-0.0016No
100SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 213274-0.5260.0051No
Table: GSEA details [plain text format]



Fig 2: IRITANI_ADPROX_VASC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: IRITANI_ADPROX_VASC: Random ES distribution   
Gene set null distribution of ES for IRITANI_ADPROX_VASC