Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | JISON_SICKLE_CELL |
| Enrichment Score (ES) | -0.47964314 |
| Normalized Enrichment Score (NES) | -1.352437 |
| Nominal p-value | 0.108333334 |
| FDR q-value | 0.3595039 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 186 | 0.510 | 0.1238 | No |
| 2 | ATOX1 | ATOX1 Entrez, Source | ATX1 antioxidant protein 1 homolog (yeast) | 585 | 0.261 | 0.1644 | No |
| 3 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 1525 | 0.133 | 0.1298 | No |
| 4 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 2561 | 0.085 | 0.0750 | No |
| 5 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 3086 | 0.069 | 0.0542 | No |
| 6 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 4741 | 0.029 | -0.0620 | No |
| 7 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 4953 | 0.025 | -0.0711 | No |
| 8 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 5729 | 0.010 | -0.1265 | No |
| 9 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 6112 | 0.003 | -0.1543 | No |
| 10 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | -0.3352 | No |
| 11 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 9379 | -0.060 | -0.3710 | No |
| 12 | IL15 | IL15 Entrez, Source | interleukin 15 | 9600 | -0.065 | -0.3699 | No |
| 13 | ADM | ADM Entrez, Source | adrenomedullin | 11063 | -0.110 | -0.4498 | Yes |
| 14 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 11158 | -0.115 | -0.4259 | Yes |
| 15 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | -0.3962 | Yes |
| 16 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12098 | -0.164 | -0.4207 | Yes |
| 17 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 12484 | -0.197 | -0.3964 | Yes |
| 18 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 12574 | -0.208 | -0.3470 | Yes |
| 19 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 12967 | -0.282 | -0.3003 | Yes |
| 20 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 12969 | -0.282 | -0.2242 | Yes |
| 21 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13211 | -0.414 | -0.1305 | Yes |
| 22 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 13267 | -0.519 | 0.0056 | Yes |
