Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_E2F1_DN |
| Enrichment Score (ES) | 0.60836524 |
| Normalized Enrichment Score (NES) | 1.8660934 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016578278 |
| FWER p-Value | 0.699 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.0648 | Yes |
| 2 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 91 | 0.673 | 0.1319 | Yes |
| 3 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 115 | 0.625 | 0.1934 | Yes |
| 4 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 127 | 0.610 | 0.2543 | Yes |
| 5 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 170 | 0.532 | 0.3050 | Yes |
| 6 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 205 | 0.482 | 0.3512 | Yes |
| 7 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 267 | 0.426 | 0.3897 | Yes |
| 8 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 309 | 0.393 | 0.4264 | Yes |
| 9 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 347 | 0.366 | 0.4607 | Yes |
| 10 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 362 | 0.357 | 0.4958 | Yes |
| 11 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 432 | 0.320 | 0.5230 | Yes |
| 12 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 602 | 0.257 | 0.5362 | Yes |
| 13 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 622 | 0.251 | 0.5603 | Yes |
| 14 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1043 | 0.177 | 0.5466 | Yes |
| 15 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 1054 | 0.177 | 0.5637 | Yes |
| 16 | GHR | GHR Entrez, Source | growth hormone receptor | 1057 | 0.176 | 0.5813 | Yes |
| 17 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 1108 | 0.170 | 0.5948 | Yes |
| 18 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 1328 | 0.149 | 0.5933 | Yes |
| 19 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1556 | 0.131 | 0.5896 | Yes |
| 20 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1627 | 0.127 | 0.5971 | Yes |
| 21 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1647 | 0.125 | 0.6084 | Yes |
| 22 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 1883 | 0.113 | 0.6021 | No |
| 23 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 2522 | 0.087 | 0.5629 | No |
| 24 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 3211 | 0.065 | 0.5178 | No |
| 25 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4036 | 0.044 | 0.4602 | No |
| 26 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 4228 | 0.039 | 0.4498 | No |
| 27 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 5506 | 0.014 | 0.3552 | No |
| 28 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 5704 | 0.011 | 0.3415 | No |
| 29 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 5856 | 0.008 | 0.3310 | No |
| 30 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6481 | -0.003 | 0.2844 | No |
| 31 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6631 | -0.006 | 0.2738 | No |
| 32 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 6658 | -0.007 | 0.2725 | No |
| 33 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 6898 | -0.010 | 0.2556 | No |
| 34 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7069 | -0.014 | 0.2442 | No |
| 35 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 7172 | -0.015 | 0.2380 | No |
| 36 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 7244 | -0.017 | 0.2344 | No |
| 37 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 7540 | -0.022 | 0.2145 | No |
| 38 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 8129 | -0.034 | 0.1737 | No |
| 39 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 9134 | -0.055 | 0.1037 | No |
| 40 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 9927 | -0.075 | 0.0517 | No |
| 41 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 11489 | -0.129 | -0.0527 | No |
| 42 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 11781 | -0.143 | -0.0601 | No |
| 43 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 11911 | -0.151 | -0.0545 | No |
| 44 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12946 | -0.276 | -0.1044 | No |
| 45 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13097 | -0.326 | -0.0827 | No |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13333 | -0.998 | 0.0007 | No |
