Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_TGFA_DN |
| Enrichment Score (ES) | 0.58306 |
| Normalized Enrichment Score (NES) | 1.8289446 |
| Nominal p-value | 0.0018656716 |
| FDR q-value | 0.022600397 |
| FWER p-Value | 0.869 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 33 | 0.905 | 0.0654 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.1145 | Yes |
| 3 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 91 | 0.673 | 0.1640 | Yes |
| 4 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 115 | 0.625 | 0.2091 | Yes |
| 5 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 127 | 0.610 | 0.2540 | Yes |
| 6 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 170 | 0.532 | 0.2907 | Yes |
| 7 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.3280 | Yes |
| 8 | CA5A | CA5A Entrez, Source | carbonic anhydrase VA, mitochondrial | 199 | 0.487 | 0.3635 | Yes |
| 9 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 202 | 0.486 | 0.3999 | Yes |
| 10 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 205 | 0.482 | 0.4359 | Yes |
| 11 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 267 | 0.426 | 0.4632 | Yes |
| 12 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 309 | 0.393 | 0.4896 | Yes |
| 13 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 347 | 0.366 | 0.5143 | Yes |
| 14 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 419 | 0.326 | 0.5334 | Yes |
| 15 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 432 | 0.320 | 0.5565 | Yes |
| 16 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 602 | 0.257 | 0.5630 | Yes |
| 17 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 638 | 0.247 | 0.5789 | Yes |
| 18 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1043 | 0.177 | 0.5618 | Yes |
| 19 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 1054 | 0.177 | 0.5743 | Yes |
| 20 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 1108 | 0.170 | 0.5831 | Yes |
| 21 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 1328 | 0.149 | 0.5777 | No |
| 22 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 1883 | 0.113 | 0.5445 | No |
| 23 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 2398 | 0.092 | 0.5127 | No |
| 24 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 2522 | 0.087 | 0.5100 | No |
| 25 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 2947 | 0.073 | 0.4836 | No |
| 26 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 3103 | 0.068 | 0.4770 | No |
| 27 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 3211 | 0.065 | 0.4739 | No |
| 28 | CRISP2 | CRISP2 Entrez, Source | cysteine-rich secretory protein 2 | 3446 | 0.059 | 0.4607 | No |
| 29 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4036 | 0.044 | 0.4197 | No |
| 30 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 4228 | 0.039 | 0.4082 | No |
| 31 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 4726 | 0.030 | 0.3731 | No |
| 32 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 5856 | 0.008 | 0.2887 | No |
| 33 | CMAH | CMAH Entrez, Source | cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) | 6224 | 0.001 | 0.2612 | No |
| 34 | LIPC | LIPC Entrez, Source | lipase, hepatic | 6430 | -0.002 | 0.2459 | No |
| 35 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6481 | -0.003 | 0.2424 | No |
| 36 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 6898 | -0.010 | 0.2119 | No |
| 37 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7069 | -0.014 | 0.2001 | No |
| 38 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 8129 | -0.034 | 0.1230 | No |
| 39 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 8862 | -0.049 | 0.0716 | No |
| 40 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 9134 | -0.055 | 0.0553 | No |
| 41 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 11157 | -0.115 | -0.0882 | No |
| 42 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 11294 | -0.120 | -0.0894 | No |
| 43 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 11781 | -0.143 | -0.1152 | No |
| 44 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 12871 | -0.259 | -0.1777 | No |
| 45 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12946 | -0.276 | -0.1626 | No |
| 46 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13097 | -0.326 | -0.1494 | No |
| 47 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13129 | -0.343 | -0.1260 | No |
| 48 | IGFALS | IGFALS Entrez, Source | insulin-like growth factor binding protein, acid labile subunit | 13179 | -0.383 | -0.1009 | No |
| 49 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 13261 | -0.509 | -0.0688 | No |
| 50 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13333 | -0.998 | 0.0007 | No |
