Details for gene set LE_MYELIN

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	LE_MYELIN_DN
Enrichment Score (ES)	0.5105269
Normalized Enrichment Score (NES)	1.7520097
Nominal p-value	0.0
FDR q-value	0.03997532
FWER p-Value	0.995

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LPL	LPL Entrez, Source	lipoprotein lipase	107	0.646	0.0590	Yes
2	PCK1	PCK1 Entrez, Source	phosphoenolpyruvate carboxykinase 1 (soluble)	127	0.610	0.1208	Yes
3	OSBPL5	OSBPL5 Entrez, Source	oxysterol binding protein-like 5	150	0.564	0.1777	Yes
4	SULT1A1	SULT1A1 Entrez, Source	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	166	0.540	0.2326	Yes
5	FADS1	FADS1 Entrez, Source	fatty acid desaturase 1	330	0.373	0.2590	Yes
6	ELOVL6	ELOVL6 Entrez, Source	ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)	433	0.319	0.2845	Yes
7	SERPIND1	SERPIND1 Entrez, Source	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	504	0.284	0.3086	Yes
8	LSS	LSS Entrez, Source	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	531	0.275	0.3352	Yes
9	LOX	LOX Entrez, Source	lysyl oxidase	558	0.267	0.3609	Yes
10	DHCR24	DHCR24 Entrez, Source	24-dehydrocholesterol reductase	561	0.267	0.3885	Yes
11	FUT8	FUT8 Entrez, Source	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)	567	0.265	0.4156	Yes
12	GJB1	GJB1 Entrez, Source	gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)	690	0.237	0.4310	Yes
13	THRSP	THRSP Entrez, Source	thyroid hormone responsive (SPOT14 homolog, rat)	889	0.197	0.4365	Yes
14	GFRA1	GFRA1 Entrez, Source	GDNF family receptor alpha 1	947	0.188	0.4517	Yes
15	NSDHL	NSDHL Entrez, Source	NAD(P) dependent steroid dehydrogenase-like	1169	0.164	0.4520	Yes
16	MYO1D	MYO1D Entrez, Source	myosin ID	1284	0.152	0.4592	Yes
17	TGFA	TGFA Entrez, Source	transforming growth factor, alpha	1441	0.140	0.4620	Yes
18	SNCA	SNCA Entrez, Source	synuclein, alpha (non A4 component of amyloid precursor)	1455	0.139	0.4754	Yes
19	SLC1A5	SLC1A5 Entrez, Source	solute carrier family 1 (neutral amino acid transporter), member 5	1487	0.136	0.4871	Yes
20	HMGCS1	HMGCS1 Entrez, Source	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)	1691	0.123	0.4846	Yes
21	SCD	SCD Entrez, Source	stearoyl-CoA desaturase (delta-9-desaturase)	1803	0.117	0.4884	Yes
22	AK3	AK3 Entrez, Source	adenylate kinase 3	1812	0.116	0.4999	Yes
23	IDI1	IDI1 Entrez, Source	isopentenyl-diphosphate delta isomerase 1	1830	0.115	0.5105	Yes
24	MVD	MVD Entrez, Source	mevalonate (diphospho) decarboxylase	1998	0.108	0.5091	No
25	CLTB	CLTB Entrez, Source	clathrin, light chain (Lcb)	2459	0.089	0.4837	No
26	ABCA2	ABCA2 Entrez, Source	ATP-binding cassette, sub-family A (ABC1), member 2	2463	0.089	0.4928	No
27	PEA15	PEA15 Entrez, Source	phosphoprotein enriched in astrocytes 15	2496	0.088	0.4995	No
28	MPZ	MPZ Entrez, Source	myelin protein zero (Charcot-Marie-Tooth neuropathy 1B)	2809	0.077	0.4839	No
29	COX8B	COX8B Entrez, Source	cytochrome c oxidase, subunit 8B pseudogene	2980	0.072	0.4785	No
30	FGL2	FGL2 Entrez, Source	fibrinogen-like 2	3128	0.068	0.4745	No
31	CYP51A1	CYP51A1 Entrez, Source	cytochrome P450, family 51, subfamily A, polypeptide 1	3141	0.067	0.4806	No
32	FGF7	FGF7 Entrez, Source	fibroblast growth factor 7 (keratinocyte growth factor)	3188	0.066	0.4840	No
33	PCYT2	PCYT2 Entrez, Source	phosphate cytidylyltransferase 2, ethanolamine	3493	0.058	0.4670	No
34	ERRFI1	ERRFI1 Entrez, Source	ERBB receptor feedback inhibitor 1	3633	0.054	0.4621	No
35	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	3822	0.050	0.4531	No
36	KCNK1	KCNK1 Entrez, Source	potassium channel, subfamily K, member 1	3913	0.047	0.4512	No
37	MYO1B	MYO1B Entrez, Source	myosin IB	4074	0.043	0.4436	No
38	FDFT1	FDFT1 Entrez, Source	farnesyl-diphosphate farnesyltransferase 1	4118	0.042	0.4447	No
39	CMTM6	CMTM6 Entrez, Source	CKLF-like MARVEL transmembrane domain containing 6	4322	0.037	0.4332	No
40	SLC25A1	SLC25A1 Entrez, Source	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	4469	0.035	0.4258	No
41	S100B	S100B Entrez, Source	S100 calcium binding protein B	4471	0.035	0.4293	No
42	SLC6A15	SLC6A15 Entrez, Source	solute carrier family 6, member 15	4739	0.029	0.4122	No
43	ADIPOQ	ADIPOQ Entrez, Source	adiponectin, C1Q and collagen domain containing	4838	0.027	0.4077	No
44	EPHB6	EPHB6 Entrez, Source	EPH receptor B6	5152	0.021	0.3863	No
45	SLCO3A1	SLCO3A1 Entrez, Source	solute carrier organic anion transporter family, member 3A1	5268	0.019	0.3796	No
46	RTN1	RTN1 Entrez, Source	reticulon 1	5323	0.018	0.3774	No
47	SCN7A	SCN7A Entrez, Source	sodium channel, voltage-gated, type VII, alpha	5325	0.018	0.3793	No
48	SC4MOL	SC4MOL Entrez, Source	sterol-C4-methyl oxidase-like	5880	0.008	0.3383	No
49	PTGDS	PTGDS Entrez, Source	prostaglandin D2 synthase 21kDa (brain)	5900	0.007	0.3376	No
50	FGF1	FGF1 Entrez, Source	fibroblast growth factor 1 (acidic)	6094	0.003	0.3234	No
51	UTRN	UTRN Entrez, Source	utrophin (homologous to dystrophin)	6212	0.001	0.3147	No
52	ZBTB16	ZBTB16 Entrez, Source	zinc finger and BTB domain containing 16	6337	-0.001	0.3054	No
53	EMP2	EMP2 Entrez, Source	epithelial membrane protein 2	6473	-0.003	0.2955	No
54	TMEM30A	TMEM30A Entrez, Source	transmembrane protein 30A	6846	-0.010	0.2685	No
55	SEMA6C	SEMA6C Entrez, Source	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	6955	-0.011	0.2615	No
56	PMP22	PMP22 Entrez, Source	peripheral myelin protein 22	6967	-0.012	0.2619	No
57	ADAM10	ADAM10 Entrez, Source	ADAM metallopeptidase domain 10	7189	-0.016	0.2469	No
58	FTH1	FTH1 Entrez, Source	ferritin, heavy polypeptide 1	7193	-0.016	0.2483	No
59	GNAI1	GNAI1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	7518	-0.022	0.2261	No
60	SIRT2	SIRT2 Entrez, Source	sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)	7882	-0.029	0.2018	No
61	BTBD14A	BTBD14A Entrez, Source	BTB (POZ) domain containing 14A	7987	-0.031	0.1972	No
62	MBP	MBP Entrez, Source	myelin basic protein	8096	-0.033	0.1925	No
63	CLDN5	CLDN5 Entrez, Source	claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)	8120	-0.034	0.1943	No
64	MYH11	MYH11 Entrez, Source	myosin, heavy chain 11, smooth muscle	8278	-0.037	0.1863	No
65	MT3	MT3 Entrez, Source	metallothionein 3 (growth inhibitory factor (neurotrophic))	8612	-0.044	0.1657	No
66	CDKN1A	CDKN1A Entrez, Source	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	8685	-0.045	0.1649	No
67	CAT	CAT Entrez, Source	catalase	8873	-0.049	0.1560	No
68	SNCG	SNCG Entrez, Source	synuclein, gamma (breast cancer-specific protein 1)	8914	-0.050	0.1581	No
69	HMGCR	HMGCR Entrez, Source	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	8972	-0.051	0.1591	No
70	S100A1	S100A1 Entrez, Source	S100 calcium binding protein A1	9993	-0.076	0.0902	No
71	LASS2	LASS2 Entrez, Source	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	10070	-0.079	0.0926	No
72	PIK3R1	PIK3R1 Entrez, Source	phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)	11304	-0.121	0.0121	No
73	MPDZ	MPDZ Entrez, Source	multiple PDZ domain protein	11344	-0.122	0.0219	No
74	SLC2A1	SLC2A1 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 1	11795	-0.144	0.0029	No
75	ABCB1A			11859	-0.148	0.0135	No
76	PCMT1	PCMT1 Entrez, Source	protein-L-isoaspartate (D-aspartate) O-methyltransferase	12428	-0.191	-0.0096	No
77	TKT	TKT Entrez, Source	transketolase (Wernicke-Korsakoff syndrome)	12523	-0.202	0.0043	No
78	NR4A2	NR4A2 Entrez, Source	nuclear receptor subfamily 4, group A, member 2	12585	-0.209	0.0214	No
79	CA3	CA3 Entrez, Source	carbonic anhydrase III, muscle specific	13129	-0.343	0.0161	No