Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetLI_FETAL_VS_WT_KIDNEY_UP
Enrichment Score (ES)0.58300865
Normalized Enrichment Score (NES)2.1099696
Nominal p-value0.0
FDR q-value0.0015555734
FWER p-Value0.02
Table: GSEA Results Summary



Fig 1: Enrichment plot: LI_FETAL_VS_WT_KIDNEY_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 7111.2760.0611Yes
2COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 2121.2540.1219Yes
3MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)310.9350.1659Yes
4DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)320.9250.2108Yes
5CRYABCRYAB
Entrez,  Source
crystallin, alpha B620.7560.2453Yes
6FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)1560.5540.2652Yes
7AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)1640.5410.2909Yes
8ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A11850.5100.3141Yes
9PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)2900.4080.3261Yes
10CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 12990.4020.3450Yes
11ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A13000.4020.3645Yes
12SLC22A5SLC22A5
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 53110.3920.3828Yes
13CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)3590.3590.3966Yes
14ANXA3ANXA3
Entrez,  Source
annexin A34840.2910.4014Yes
15CREBL2CREBL2
Entrez,  Source
cAMP responsive element binding protein-like 24940.2880.4147Yes
16ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule5070.2820.4275Yes
17TPST1TPST1
Entrez,  Source
tyrosylprotein sulfotransferase 16170.2530.4315Yes
18SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 46230.2510.4433Yes
19HRSP12HRSP12
Entrez,  Source
heat-responsive protein 126540.2440.4529Yes
20ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)6580.2440.4645Yes
21LEPRLEPR
Entrez,  Source
leptin receptor6850.2380.4741Yes
22APOMAPOM
Entrez,  Source
apolipoprotein M6870.2380.4856Yes
23ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 17220.2310.4942Yes
24CLDN3CLDN3
Entrez,  Source
claudin 37450.2280.5036Yes
25HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)7750.2210.5121Yes
26CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 17960.2150.5210Yes
27AGRINAGRIN
Entrez,  Source
agrin8010.2130.5311Yes
28SEPP1SEPP1
Entrez,  Source
selenoprotein P, plasma, 18230.2090.5397Yes
29SCP2SCP2
Entrez,  Source
sterol carrier protein 28900.1970.5442Yes
30CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)9510.1880.5488Yes
31ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide9730.1860.5562Yes
32MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase10000.1830.5631Yes
33TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)10520.1770.5679Yes
34ANXA4ANXA4
Entrez,  Source
annexin A411090.1700.5719Yes
35TSPOTSPO
Entrez,  Source
translocator protein (18kDa)12650.1540.5676Yes
36TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 213000.1500.5724Yes
37CTSHCTSH
Entrez,  Source
cathepsin H14010.1430.5717Yes
38ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b14270.1400.5767Yes
39TGOLN2TGOLN2
Entrez,  Source
trans-golgi network protein 214340.1400.5830Yes
40DYNC2LI1DYNC2LI1
Entrez,  Source
dynein, cytoplasmic 2, light intermediate chain 115820.1290.5782No
41ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 116270.1270.5810No
42PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 716960.1230.5818No
43HERPUD1HERPUD1
Entrez,  Source
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 118610.1140.5749No
44PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)20300.1060.5674No
45PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A23130.0950.5507No
46SPP1SPP1
Entrez,  Source
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)23450.0940.5529No
47ATP1A1ATP1A1
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 1 polypeptide23600.0930.5564No
48SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 123610.0930.5609No
49APOEAPOE
Entrez,  Source
apolipoprotein E26190.0830.5455No
50CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta26280.0830.5489No
51GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 328160.0770.5385No
52SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein28180.0770.5421No
53CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)28480.0760.5436No
54ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)30400.0700.5326No
55CASTCAST
Entrez,  Source
calpastatin30520.0700.5351No
56AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase30860.0690.5359No
57FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase31020.0680.5381No
58BPGMBPGM
Entrez,  Source
2,3-bisphosphoglycerate mutase33580.0610.5218No
59KIFC3KIFC3
Entrez,  Source
kinesin family member C336360.0540.5035No
60SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 236850.0530.5024No
61SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A37760.0510.4981No
62PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A41610.0410.4710No
63DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)41980.0400.4702No
64LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 242800.0380.4660No
65KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)44420.0350.4555No
66S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1046300.0310.4429No
67SYNGR2SYNGR2
Entrez,  Source
synaptogyrin 250710.0230.4107No
68FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)53810.0170.3882No
69UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase53840.0170.3889No
70FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C54360.0160.3858No
71CLUCLU
Entrez,  Source
clusterin54430.0160.3861No
72SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like58800.0080.3535No
73DUSP9DUSP9
Entrez,  Source
dual specificity phosphatase 959740.0060.3468No
74TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 262450.0010.3264No
75IFIT1IFIT1
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 16477-0.0030.3091No
76ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)6582-0.0050.3015No
77IL1R1IL1R1
Entrez,  Source
interleukin 1 receptor, type I6718-0.0070.2917No
78TOB1TOB1
Entrez,  Source
transducer of ERBB2, 16785-0.0090.2871No
79PMP22PMP22
Entrez,  Source
peripheral myelin protein 226967-0.0120.2740No
80CAV2CAV2
Entrez,  Source
caveolin 27012-0.0120.2713No
81TCF21TCF21
Entrez,  Source
transcription factor 217391-0.0200.2436No
82TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 57449-0.0210.2403No
83GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 17518-0.0220.2363No
84GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 117863-0.0280.2116No
85PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)8424-0.0400.1713No
86MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 28516-0.0420.1664No
87ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 68557-0.0430.1655No
88ITM2BITM2B
Entrez,  Source
integral membrane protein 2B8720-0.0460.1554No
89PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 29059-0.0530.1325No
90PODXLPODXL
Entrez,  Source
podocalyxin-like9478-0.0620.1039No
91GNG12GNG12
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 129591-0.0650.0986No
92NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)9848-0.0720.0828No
93NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 39971-0.0760.0772No
94ANGPT1ANGPT1
Entrez,  Source
angiopoietin 110068-0.0790.0738No
95CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10104-0.0790.0750No
96LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog10258-0.0830.0674No
97SERINC5SERINC5
Entrez,  Source
serine incorporator 510779-0.1000.0330No
98TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)11338-0.122-0.0033No
99IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 211426-0.126-0.0037No
100ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)11435-0.1260.0018No
101MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12058-0.161-0.0374No
102PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase12137-0.167-0.0352No
103VEGFVEGF
Entrez,  Source
vascular endothelial growth factor12221-0.173-0.0330No
104SLC35A3SLC35A3
Entrez,  Source
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A312262-0.176-0.0275No
105GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha12556-0.205-0.0397No
106XBP1XBP1
Entrez,  Source
X-box binding protein 112599-0.210-0.0327No
107PRPS2PRPS2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 212773-0.237-0.0342No
108SLC30A1SLC30A1
Entrez,  Source
solute carrier family 30 (zinc transporter), member 112795-0.240-0.0242No
109ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 313175-0.381-0.0343No
110VLDLRVLDLR
Entrez,  Source
very low density lipoprotein receptor13233-0.442-0.0172No
111PPP1R3CPPP1R3C
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3C13269-0.5220.0055No
Table: GSEA details [plain text format]



Fig 2: LI_FETAL_VS_WT_KIDNEY_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LI_FETAL_VS_WT_KIDNEY_UP: Random ES distribution   
Gene set null distribution of ES for LI_FETAL_VS_WT_KIDNEY_UP