Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LYSINE_DEGRADATION |
| Enrichment Score (ES) | 0.7019926 |
| Normalized Enrichment Score (NES) | 1.871793 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016669264 |
| FWER p-Value | 0.681 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BBOX1 | BBOX1 Entrez, Source | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 78 | 0.695 | 0.1660 | Yes |
| 2 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.2842 | Yes |
| 3 | AADAT | AADAT Entrez, Source | aminoadipate aminotransferase | 204 | 0.482 | 0.4021 | Yes |
| 4 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 346 | 0.367 | 0.4823 | Yes |
| 5 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 375 | 0.349 | 0.5665 | Yes |
| 6 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.6236 | Yes |
| 7 | SDS | SDS Entrez, Source | serine dehydratase | 1007 | 0.182 | 0.6326 | Yes |
| 8 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 1343 | 0.147 | 0.6438 | Yes |
| 9 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.6722 | Yes |
| 10 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1482 | 0.136 | 0.7020 | Yes |
| 11 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 2173 | 0.101 | 0.6751 | No |
| 12 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.6685 | No |
| 13 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 2893 | 0.074 | 0.6608 | No |
| 14 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 3710 | 0.052 | 0.6124 | No |
| 15 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 4375 | 0.036 | 0.5715 | No |
| 16 | EHMT2 | EHMT2 Entrez, Source | euchromatic histone-lysine N-methyltransferase 2 | 6753 | -0.008 | 0.3951 | No |
| 17 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 7827 | -0.028 | 0.3214 | No |
| 18 | TMLHE | TMLHE Entrez, Source | trimethyllysine hydroxylase, epsilon | 8430 | -0.040 | 0.2861 | No |
| 19 | PLOD3 | PLOD3 Entrez, Source | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 9471 | -0.062 | 0.2234 | No |
| 20 | PLOD1 | PLOD1 Entrez, Source | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 11305 | -0.121 | 0.1157 | No |
| 21 | SHMT2 | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 11904 | -0.150 | 0.1079 | No |
