Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | MONOCARBOXYLIC_ACID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.5817579 |
| Normalized Enrichment Score (NES) | 1.9129496 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01115716 |
| FWER p-Value | 0.473 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 18 | 1.071 | 0.0841 | Yes |
| 2 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 46 | 0.834 | 0.1486 | Yes |
| 3 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 47 | 0.829 | 0.2147 | Yes |
| 4 | BBOX1 | BBOX1 Entrez, Source | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 78 | 0.695 | 0.2679 | Yes |
| 5 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 84 | 0.686 | 0.3222 | Yes |
| 6 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 97 | 0.667 | 0.3745 | Yes |
| 7 | AGXT | AGXT Entrez, Source | alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) | 212 | 0.475 | 0.4038 | Yes |
| 8 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 330 | 0.373 | 0.4247 | Yes |
| 9 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 346 | 0.367 | 0.4529 | Yes |
| 10 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 350 | 0.365 | 0.4817 | Yes |
| 11 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 379 | 0.348 | 0.5073 | Yes |
| 12 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 490 | 0.289 | 0.5221 | Yes |
| 13 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 595 | 0.258 | 0.5348 | Yes |
| 14 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 602 | 0.257 | 0.5549 | Yes |
| 15 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 817 | 0.210 | 0.5555 | Yes |
| 16 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 886 | 0.197 | 0.5661 | Yes |
| 17 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 934 | 0.190 | 0.5777 | Yes |
| 18 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | 0.5818 | Yes |
| 19 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1544 | 0.132 | 0.5563 | No |
| 20 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 1689 | 0.123 | 0.5553 | No |
| 21 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1715 | 0.122 | 0.5632 | No |
| 22 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2111 | 0.103 | 0.5417 | No |
| 23 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 2431 | 0.090 | 0.5248 | No |
| 24 | ACOT12 | ACOT12 Entrez, Source | acyl-CoA thioesterase 12 | 2485 | 0.088 | 0.5279 | No |
| 25 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 3002 | 0.071 | 0.4947 | No |
| 26 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 3091 | 0.069 | 0.4936 | No |
| 27 | ADIPOR1 | ADIPOR1 Entrez, Source | adiponectin receptor 1 | 3394 | 0.060 | 0.4757 | No |
| 28 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 3505 | 0.057 | 0.4719 | No |
| 29 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 3581 | 0.055 | 0.4707 | No |
| 30 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 3794 | 0.050 | 0.4588 | No |
| 31 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 3966 | 0.045 | 0.4495 | No |
| 32 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 4489 | 0.034 | 0.4129 | No |
| 33 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 5165 | 0.021 | 0.3638 | No |
| 34 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 5216 | 0.020 | 0.3616 | No |
| 35 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 5265 | 0.019 | 0.3595 | No |
| 36 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 5506 | 0.014 | 0.3426 | No |
| 37 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 5532 | 0.014 | 0.3418 | No |
| 38 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 5556 | 0.014 | 0.3412 | No |
| 39 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 5880 | 0.008 | 0.3175 | No |
| 40 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 5900 | 0.007 | 0.3166 | No |
| 41 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 5998 | 0.005 | 0.3097 | No |
| 42 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 6295 | -0.000 | 0.2874 | No |
| 43 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 6415 | -0.002 | 0.2786 | No |
| 44 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7069 | -0.014 | 0.2305 | No |
| 45 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 7494 | -0.022 | 0.2003 | No |
| 46 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 7978 | -0.031 | 0.1664 | No |
| 47 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 8129 | -0.034 | 0.1578 | No |
| 48 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 8306 | -0.037 | 0.1476 | No |
| 49 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8340 | -0.038 | 0.1481 | No |
| 50 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 9134 | -0.055 | 0.0928 | No |
| 51 | ARPP-19 | ARPP-19 Entrez, Source | - | 9233 | -0.057 | 0.0899 | No |
| 52 | NR1H4 | NR1H4 Entrez, Source | nuclear receptor subfamily 1, group H, member 4 | 9939 | -0.075 | 0.0428 | No |
| 53 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 10884 | -0.104 | -0.0200 | No |
| 54 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11096 | -0.112 | -0.0269 | No |
| 55 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 11617 | -0.134 | -0.0554 | No |
| 56 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 11938 | -0.152 | -0.0673 | No |
| 57 | MIF | MIF Entrez, Source | macrophage migration inhibitory factor (glycosylation-inhibiting factor) | 12291 | -0.179 | -0.0796 | No |
| 58 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 12405 | -0.189 | -0.0730 | No |
| 59 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 13052 | -0.307 | -0.0972 | No |
| 60 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 13138 | -0.352 | -0.0755 | No |
| 61 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 13261 | -0.509 | -0.0441 | No |
| 62 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13307 | -0.629 | 0.0026 | No |
