Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | MOREAUX_TACI_HI_VS_LOW_DN |
| Enrichment Score (ES) | -0.547906 |
| Normalized Enrichment Score (NES) | -1.9119363 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.019153897 |
| FWER p-Value | 0.358 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 313 | 0.388 | 0.0254 | No |
| 2 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 1051 | 0.177 | -0.0079 | No |
| 3 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1511 | 0.134 | -0.0255 | No |
| 4 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 1760 | 0.119 | -0.0293 | No |
| 5 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 3506 | 0.057 | -0.1535 | No |
| 6 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 3887 | 0.048 | -0.1761 | No |
| 7 | TMEM165 | TMEM165 Entrez, Source | transmembrane protein 165 | 4142 | 0.041 | -0.1900 | No |
| 8 | G3BP | G3BP Entrez, Source | - | 4201 | 0.039 | -0.1894 | No |
| 9 | WDR61 | WDR61 Entrez, Source | WD repeat domain 61 | 4950 | 0.025 | -0.2425 | No |
| 10 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 5360 | 0.018 | -0.2711 | No |
| 11 | FIBP | FIBP Entrez, Source | fibroblast growth factor (acidic) intracellular binding protein | 5466 | 0.016 | -0.2771 | No |
| 12 | SLC33A1 | SLC33A1 Entrez, Source | solute carrier family 33 (acetyl-CoA transporter), member 1 | 6303 | -0.000 | -0.3400 | No |
| 13 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 6739 | -0.008 | -0.3718 | No |
| 14 | C3ORF64 | C3ORF64 Entrez, Source | chromosome 3 open reading frame 64 | 6818 | -0.009 | -0.3765 | No |
| 15 | KEAP1 | KEAP1 Entrez, Source | kelch-like ECH-associated protein 1 | 7472 | -0.021 | -0.4230 | No |
| 16 | UPF3A | UPF3A Entrez, Source | UPF3 regulator of nonsense transcripts homolog A (yeast) | 7537 | -0.022 | -0.4250 | No |
| 17 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 7632 | -0.024 | -0.4291 | No |
| 18 | NMT1 | NMT1 Entrez, Source | N-myristoyltransferase 1 | 8220 | -0.036 | -0.4688 | No |
| 19 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 8251 | -0.036 | -0.4664 | No |
| 20 | NCLN | NCLN Entrez, Source | nicalin homolog (zebrafish) | 8405 | -0.039 | -0.4730 | No |
| 21 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 9220 | -0.056 | -0.5272 | No |
| 22 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 9365 | -0.060 | -0.5305 | No |
| 23 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 9597 | -0.065 | -0.5397 | Yes |
| 24 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 9675 | -0.067 | -0.5370 | Yes |
| 25 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 9677 | -0.067 | -0.5286 | Yes |
| 26 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9796 | -0.071 | -0.5286 | Yes |
| 27 | ZCCHC10 | ZCCHC10 Entrez, Source | zinc finger, CCHC domain containing 10 | 9917 | -0.074 | -0.5282 | Yes |
| 28 | CCT2 | CCT2 Entrez, Source | chaperonin containing TCP1, subunit 2 (beta) | 10085 | -0.079 | -0.5309 | Yes |
| 29 | MATR3 | MATR3 Entrez, Source | matrin 3 | 10114 | -0.079 | -0.5230 | Yes |
| 30 | THYN1 | THYN1 Entrez, Source | thymocyte nuclear protein 1 | 10224 | -0.082 | -0.5208 | Yes |
| 31 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10350 | -0.086 | -0.5194 | Yes |
| 32 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 10402 | -0.087 | -0.5123 | Yes |
| 33 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 10530 | -0.091 | -0.5104 | Yes |
| 34 | TAF2 | TAF2 Entrez, Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 10729 | -0.098 | -0.5129 | Yes |
| 35 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 10771 | -0.100 | -0.5034 | Yes |
| 36 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 10931 | -0.106 | -0.5021 | Yes |
| 37 | IK | IK Entrez, Source | IK cytokine, down-regulator of HLA II | 10954 | -0.107 | -0.4903 | Yes |
| 38 | BTBD1 | BTBD1 Entrez, Source | BTB (POZ) domain containing 1 | 11370 | -0.123 | -0.5060 | Yes |
| 39 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 11423 | -0.126 | -0.4941 | Yes |
| 40 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 11511 | -0.130 | -0.4843 | Yes |
| 41 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11541 | -0.131 | -0.4700 | Yes |
| 42 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 11573 | -0.132 | -0.4557 | Yes |
| 43 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 11603 | -0.133 | -0.4410 | Yes |
| 44 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 11685 | -0.137 | -0.4298 | Yes |
| 45 | MINA | MINA Entrez, Source | MYC induced nuclear antigen | 11787 | -0.144 | -0.4193 | Yes |
| 46 | NUDT5 | NUDT5 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 5 | 11827 | -0.146 | -0.4038 | Yes |
| 47 | ACTL6A | ACTL6A Entrez, Source | actin-like 6A | 11977 | -0.156 | -0.3954 | Yes |
| 48 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 11993 | -0.157 | -0.3768 | Yes |
| 49 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 12016 | -0.158 | -0.3585 | Yes |
| 50 | EIF3S4 | EIF3S4 Entrez, Source | eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa | 12102 | -0.164 | -0.3442 | Yes |
| 51 | DDX18 | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 12109 | -0.165 | -0.3238 | Yes |
| 52 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 12177 | -0.170 | -0.3075 | Yes |
| 53 | PAPD4 | PAPD4 Entrez, Source | PAP associated domain containing 4 | 12288 | -0.178 | -0.2933 | Yes |
| 54 | STAM2 | STAM2 Entrez, Source | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 12300 | -0.180 | -0.2715 | Yes |
| 55 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 12468 | -0.195 | -0.2595 | Yes |
| 56 | IFT74 | IFT74 Entrez, Source | intraflagellar transport 74 homolog (Chlamydomonas) | 12675 | -0.221 | -0.2472 | Yes |
| 57 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 12730 | -0.229 | -0.2224 | Yes |
| 58 | NUDCD2 | NUDCD2 Entrez, Source | NudC domain containing 2 | 12835 | -0.250 | -0.1988 | Yes |
| 59 | GLT8D1 | GLT8D1 Entrez, Source | glycosyltransferase 8 domain containing 1 | 12889 | -0.264 | -0.1695 | Yes |
| 60 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12914 | -0.270 | -0.1373 | Yes |
| 61 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.1047 | Yes |
| 62 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.0720 | Yes |
| 63 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 13036 | -0.304 | -0.0368 | Yes |
| 64 | CCDC5 | CCDC5 Entrez, Source | coiled-coil domain containing 5 (spindle associated) | 13247 | -0.474 | 0.0072 | Yes |
