Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | MRNA_PROCESSING_GO_0006397 |
| Enrichment Score (ES) | -0.5727551 |
| Normalized Enrichment Score (NES) | -1.7402381 |
| Nominal p-value | 0.006880734 |
| FDR q-value | 0.07856947 |
| FWER p-Value | 0.974 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | -0.0303 | No |
| 2 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 4049 | 0.043 | -0.2419 | No |
| 3 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 4346 | 0.037 | -0.2537 | No |
| 4 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 4464 | 0.035 | -0.2526 | No |
| 5 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 5776 | 0.009 | -0.3484 | No |
| 6 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 6401 | -0.002 | -0.3948 | No |
| 7 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.4113 | No |
| 8 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 6946 | -0.011 | -0.4305 | No |
| 9 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 7029 | -0.013 | -0.4330 | No |
| 10 | SLU7 | SLU7 Entrez, Source | - | 8593 | -0.043 | -0.5381 | No |
| 11 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 9013 | -0.052 | -0.5546 | No |
| 12 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 9255 | -0.057 | -0.5565 | Yes |
| 13 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.5416 | Yes |
| 14 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 9303 | -0.058 | -0.5269 | Yes |
| 15 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 9480 | -0.062 | -0.5223 | Yes |
| 16 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9796 | -0.071 | -0.5258 | Yes |
| 17 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10089 | -0.079 | -0.5252 | Yes |
| 18 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10252 | -0.083 | -0.5137 | Yes |
| 19 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10349 | -0.086 | -0.4964 | Yes |
| 20 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 10840 | -0.103 | -0.5039 | Yes |
| 21 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 10842 | -0.103 | -0.4747 | Yes |
| 22 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11175 | -0.115 | -0.4667 | Yes |
| 23 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.4360 | Yes |
| 24 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11293 | -0.120 | -0.4079 | Yes |
| 25 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.4182 | Yes |
| 26 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12145 | -0.168 | -0.3782 | Yes |
| 27 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12161 | -0.169 | -0.3311 | Yes |
| 28 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12304 | -0.180 | -0.2904 | Yes |
| 29 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.2406 | Yes |
| 30 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12402 | -0.188 | -0.1919 | Yes |
| 31 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12534 | -0.203 | -0.1439 | Yes |
| 32 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12665 | -0.219 | -0.0910 | Yes |
| 33 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12732 | -0.229 | -0.0304 | Yes |
| 34 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 12901 | -0.267 | 0.0331 | Yes |
