Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetNETPATH_ALPHA6_BETA4_INTEGRIN_PATHWAY
Enrichment Score (ES)0.54554754
Normalized Enrichment Score (NES)1.7037581
Nominal p-value0.0017152659
FDR q-value0.053800303
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: NETPATH_ALPHA6_BETA4_INTEGRIN_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1VIMVIM
Entrez,  Source
vimentin71.3910.1841Yes
2LAMC2LAMC2
Entrez,  Source
laminin, gamma 2231.0210.3185Yes
3ITGB4ITGB4
Entrez,  Source
integrin, beta 42660.4260.3569Yes
4LAMA5LAMA5
Entrez,  Source
laminin, alpha 53680.3520.3960Yes
5LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)5300.2750.4203Yes
6LAMB2LAMB2
Entrez,  Source
laminin, beta 2 (laminin S)5900.2600.4504Yes
7PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6430.2470.4792Yes
8ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)7380.2290.5025Yes
9RTKNRTKN
Entrez,  Source
rhotekin12330.1580.4863Yes
10MMP7MMP7
Entrez,  Source
matrix metallopeptidase 7 (matrilysin, uterine)13850.1440.4940Yes
11PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha14230.1410.5099Yes
12YWHAQYWHAQ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide14470.1390.5266Yes
13BADBAD
Entrez,  Source
BCL2-antagonist of cell death15300.1330.5380Yes
14AKT1AKT1
Entrez,  Source
v-akt murine thymoma viral oncogene homolog 116520.1250.5455Yes
15ARAR
Entrez,  Source
androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)18860.1120.5429No
16FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES26230.0830.4986No
17PIK3R3PIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)27440.0790.5000No
18LAMA3LAMA3
Entrez,  Source
laminin, alpha 333440.0610.4631No
19CLCA2CLCA2
Entrez,  Source
chloride channel, calcium activated, family member 233500.0610.4708No
20SRCSRC
Entrez,  Source
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)34200.0600.4736No
21SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)37900.0500.4525No
22CASP3CASP3
Entrez,  Source
caspase 3, apoptosis-related cysteine peptidase46060.0320.3954No
23YWHABYWHAB
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide60580.0040.2868No
24SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)62130.0010.2753No
25PIK3R2PIK3R2
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)6330-0.0010.2667No
26PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 26465-0.0030.2570No
27EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E6696-0.0070.2406No
28EIF4EBP1EIF4EBP1
Entrez,  Source
eukaryotic translation initiation factor 4E binding protein 16902-0.0110.2266No
29CD151CD151
Entrez,  Source
CD151 molecule (Raph blood group)6998-0.0120.2210No
30ITGA6ITGA6
Entrez,  Source
integrin, alpha 67051-0.0130.2189No
31DSPDSP
Entrez,  Source
desmoplakin7304-0.0180.2023No
32NTN1NTN1
Entrez,  Source
netrin 17361-0.0190.2006No
33YWHAHYWHAH
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide7564-0.0230.1884No
34PRKCDPRKCD
Entrez,  Source
protein kinase C, delta7739-0.0260.1788No
35SHC1SHC1
Entrez,  Source
SHC (Src homology 2 domain containing) transforming protein 17776-0.0270.1797No
36PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa8108-0.0340.1592No
37YWHAZYWHAZ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide8135-0.0340.1618No
38RHOARHOA
Entrez,  Source
ras homolog gene family, member A8243-0.0360.1586No
39ITGB4BPITGB4BP
Entrez,  Source
integrin beta 4 binding protein8401-0.0390.1520No
40YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide8704-0.0450.1353No
41RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)9101-0.0540.1127No
42PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide9133-0.0550.1176No
43RPSARPSA
Entrez,  Source
ribosomal protein SA9241-0.0570.1171No
44PIK3CBPIK3CB
Entrez,  Source
phosphoinositide-3-kinase, catalytic, beta polypeptide9345-0.0590.1172No
45METAP2METAP2
Entrez,  Source
methionyl aminopeptidase 29592-0.0650.1073No
46IRS1IRS1
Entrez,  Source
insulin receptor substrate 111226-0.117-0.0000No
47PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)11304-0.1210.0102No
48GRB2GRB2
Entrez,  Source
growth factor receptor-bound protein 211803-0.145-0.0081No
49FRAP1FRAP1
Entrez,  Source
FK506 binding protein 12-rapamycin associated protein 111920-0.1510.0033No
50EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)12946-0.276-0.0372No
51LAMB3LAMB3
Entrez,  Source
laminin, beta 313259-0.5040.0062No
Table: GSEA details [plain text format]



Fig 2: NETPATH_ALPHA6_BETA4_INTEGRIN_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NETPATH_ALPHA6_BETA4_INTEGRIN_PATHWAY: Random ES distribution   
Gene set null distribution of ES for NETPATH_ALPHA6_BETA4_INTEGRIN_PATHWAY