Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NETPATH_ANDROGEN_RECEPTOR_PATHWAY_DOWN |
| Enrichment Score (ES) | 0.4834612 |
| Normalized Enrichment Score (NES) | 1.7267207 |
| Nominal p-value | 0.0016778524 |
| FDR q-value | 0.046798054 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 2 | 1.623 | 0.0970 | Yes |
| 2 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 21 | 1.039 | 0.1578 | Yes |
| 3 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 49 | 0.810 | 0.2042 | Yes |
| 4 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 61 | 0.759 | 0.2488 | Yes |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 107 | 0.646 | 0.2841 | Yes |
| 6 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 318 | 0.386 | 0.2914 | Yes |
| 7 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 336 | 0.371 | 0.3123 | Yes |
| 8 | HRG | HRG Entrez, Source | histidine-rich glycoprotein | 515 | 0.280 | 0.3156 | Yes |
| 9 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 533 | 0.274 | 0.3307 | Yes |
| 10 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 592 | 0.258 | 0.3418 | Yes |
| 11 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 738 | 0.229 | 0.3445 | Yes |
| 12 | GCHFR | GCHFR Entrez, Source | GTP cyclohydrolase I feedback regulator | 762 | 0.223 | 0.3561 | Yes |
| 13 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 783 | 0.219 | 0.3677 | Yes |
| 14 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 793 | 0.215 | 0.3799 | Yes |
| 15 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 796 | 0.215 | 0.3926 | Yes |
| 16 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 807 | 0.212 | 0.4045 | Yes |
| 17 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 862 | 0.201 | 0.4125 | Yes |
| 18 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.4201 | Yes |
| 19 | CAMK2N2 | CAMK2N2 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 2 | 1127 | 0.168 | 0.4142 | Yes |
| 20 | FN1 | FN1 Entrez, Source | fibronectin 1 | 1246 | 0.156 | 0.4147 | Yes |
| 21 | RALB | RALB Entrez, Source | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 1279 | 0.153 | 0.4214 | Yes |
| 22 | SLC44A1 | SLC44A1 Entrez, Source | solute carrier family 44, member 1 | 1330 | 0.149 | 0.4265 | Yes |
| 23 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 1448 | 0.139 | 0.4260 | Yes |
| 24 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1482 | 0.136 | 0.4316 | Yes |
| 25 | CRAT | CRAT Entrez, Source | carnitine acetyltransferase | 1485 | 0.136 | 0.4396 | Yes |
| 26 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1511 | 0.134 | 0.4458 | Yes |
| 27 | SMPD1 | SMPD1 Entrez, Source | sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) | 1607 | 0.128 | 0.4462 | Yes |
| 28 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 1666 | 0.124 | 0.4493 | Yes |
| 29 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 1682 | 0.124 | 0.4556 | Yes |
| 30 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 1732 | 0.121 | 0.4591 | Yes |
| 31 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 1760 | 0.119 | 0.4642 | Yes |
| 32 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1803 | 0.117 | 0.4680 | Yes |
| 33 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 1889 | 0.112 | 0.4683 | Yes |
| 34 | FZD3 | FZD3 Entrez, Source | frizzled homolog 3 (Drosophila) | 1904 | 0.111 | 0.4739 | Yes |
| 35 | PAMCI | PAMCI Entrez, Source | peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor | 2043 | 0.106 | 0.4698 | Yes |
| 36 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 2064 | 0.105 | 0.4746 | Yes |
| 37 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 2076 | 0.105 | 0.4800 | Yes |
| 38 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 2261 | 0.097 | 0.4719 | Yes |
| 39 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2345 | 0.094 | 0.4712 | Yes |
| 40 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 2357 | 0.093 | 0.4760 | Yes |
| 41 | P2RY2 | P2RY2 Entrez, Source | purinergic receptor P2Y, G-protein coupled, 2 | 2405 | 0.092 | 0.4779 | Yes |
| 42 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 2422 | 0.091 | 0.4821 | Yes |
| 43 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 2489 | 0.088 | 0.4824 | Yes |
| 44 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.4835 | Yes |
| 45 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 2692 | 0.081 | 0.4772 | No |
| 46 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 2744 | 0.079 | 0.4780 | No |
| 47 | OXT | OXT Entrez, Source | oxytocin, prepro- (neurophysin I) | 2750 | 0.079 | 0.4823 | No |
| 48 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 3429 | 0.060 | 0.4347 | No |
| 49 | ACP6 | ACP6 Entrez, Source | acid phosphatase 6, lysophosphatidic | 3521 | 0.057 | 0.4312 | No |
| 50 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 3618 | 0.054 | 0.4272 | No |
| 51 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 3759 | 0.051 | 0.4197 | No |
| 52 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3799 | 0.050 | 0.4197 | No |
| 53 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3890 | 0.048 | 0.4158 | No |
| 54 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 3904 | 0.047 | 0.4176 | No |
| 55 | CNTFR | CNTFR Entrez, Source | ciliary neurotrophic factor receptor | 3971 | 0.045 | 0.4153 | No |
| 56 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 4035 | 0.044 | 0.4132 | No |
| 57 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 4556 | 0.033 | 0.3758 | No |
| 58 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4778 | 0.028 | 0.3608 | No |
| 59 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 5184 | 0.021 | 0.3314 | No |
| 60 | ASNS | ASNS Entrez, Source | asparagine synthetase | 5217 | 0.020 | 0.3302 | No |
| 61 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 5285 | 0.019 | 0.3263 | No |
| 62 | CGA | CGA Entrez, Source | glycoprotein hormones, alpha polypeptide | 5370 | 0.017 | 0.3210 | No |
| 63 | CLU | CLU Entrez, Source | clusterin | 5443 | 0.016 | 0.3165 | No |
| 64 | SNX1 | SNX1 Entrez, Source | sorting nexin 1 | 5489 | 0.015 | 0.3140 | No |
| 65 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 5563 | 0.013 | 0.3093 | No |
| 66 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5643 | 0.012 | 0.3040 | No |
| 67 | CAMK2N1 | CAMK2N1 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 5852 | 0.008 | 0.2888 | No |
| 68 | BCHE | BCHE Entrez, Source | butyrylcholinesterase | 5853 | 0.008 | 0.2893 | No |
| 69 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 5920 | 0.007 | 0.2847 | No |
| 70 | LRRN1 | LRRN1 Entrez, Source | leucine rich repeat neuronal 1 | 6069 | 0.004 | 0.2737 | No |
| 71 | MBTPS1 | MBTPS1 Entrez, Source | membrane-bound transcription factor peptidase, site 1 | 6090 | 0.003 | 0.2724 | No |
| 72 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 6140 | 0.002 | 0.2689 | No |
| 73 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 6599 | -0.006 | 0.2346 | No |
| 74 | JUN | JUN Entrez, Source | jun oncogene | 6649 | -0.006 | 0.2313 | No |
| 75 | SNRK | SNRK Entrez, Source | SNF related kinase | 6919 | -0.011 | 0.2116 | No |
| 76 | GATA2 | GATA2 Entrez, Source | GATA binding protein 2 | 6947 | -0.011 | 0.2102 | No |
| 77 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 7067 | -0.014 | 0.2020 | No |
| 78 | HMGCL | HMGCL Entrez, Source | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 7083 | -0.014 | 0.2017 | No |
| 79 | PLEKHB1 | PLEKHB1 Entrez, Source | pleckstrin homology domain containing, family B (evectins) member 1 | 7270 | -0.017 | 0.1887 | No |
| 80 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 7478 | -0.021 | 0.1743 | No |
| 81 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 7532 | -0.022 | 0.1716 | No |
| 82 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 8141 | -0.034 | 0.1277 | No |
| 83 | PDYN | PDYN Entrez, Source | prodynorphin | 8248 | -0.036 | 0.1219 | No |
| 84 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 8318 | -0.038 | 0.1189 | No |
| 85 | SMARCD3 | SMARCD3 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 8627 | -0.044 | 0.0983 | No |
| 86 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | 0.0967 | No |
| 87 | GRN | GRN Entrez, Source | granulin | 8784 | -0.047 | 0.0921 | No |
| 88 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 8793 | -0.048 | 0.0943 | No |
| 89 | STAR | STAR Entrez, Source | steroidogenic acute regulator | 8839 | -0.049 | 0.0938 | No |
| 90 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 8942 | -0.051 | 0.0892 | No |
| 91 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 8961 | -0.051 | 0.0909 | No |
| 92 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 9817 | -0.071 | 0.0305 | No |
| 93 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 10340 | -0.086 | -0.0038 | No |
| 94 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 10608 | -0.094 | -0.0184 | No |
| 95 | SLC20A2 | SLC20A2 Entrez, Source | solute carrier family 20 (phosphate transporter), member 2 | 10867 | -0.104 | -0.0317 | No |
| 96 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 10944 | -0.106 | -0.0311 | No |
| 97 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 11129 | -0.113 | -0.0382 | No |
| 98 | PRKD1 | PRKD1 Entrez, Source | protein kinase D1 | 11159 | -0.115 | -0.0335 | No |
| 99 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 11229 | -0.117 | -0.0317 | No |
| 100 | ACPP | ACPP Entrez, Source | acid phosphatase, prostate | 11357 | -0.123 | -0.0340 | No |
| 101 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 11736 | -0.140 | -0.0542 | No |
| 102 | COLEC12 | COLEC12 Entrez, Source | collectin sub-family member 12 | 11746 | -0.141 | -0.0464 | No |
| 103 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 11961 | -0.154 | -0.0534 | No |
| 104 | NFIX | NFIX Entrez, Source | nuclear factor I/X (CCAAT-binding transcription factor) | 12029 | -0.159 | -0.0489 | No |
| 105 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.0550 | No |
| 106 | FOXQ1 | FOXQ1 Entrez, Source | forkhead box Q1 | 12350 | -0.183 | -0.0516 | No |
| 107 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 12512 | -0.201 | -0.0517 | No |
| 108 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 12827 | -0.248 | -0.0606 | No |
| 109 | TXNIP | TXNIP Entrez, Source | thioredoxin interacting protein | 13000 | -0.292 | -0.0561 | No |
| 110 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 13130 | -0.345 | -0.0452 | No |
| 111 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 13207 | -0.413 | -0.0263 | No |
| 112 | GSTA2 | GSTA2 Entrez, Source | glutathione S-transferase A2 | 13300 | -0.608 | 0.0032 | No |
