Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NETPATH_IL_4_PATHWAY_DOWN |
| Enrichment Score (ES) | 0.64615935 |
| Normalized Enrichment Score (NES) | 2.0484154 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0027240475 |
| FWER p-Value | 0.06 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 7 | 1.391 | 0.1355 | Yes |
| 2 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 27 | 0.963 | 0.2282 | Yes |
| 3 | CD9 | CD9 Entrez, Source | CD9 molecule | 41 | 0.871 | 0.3124 | Yes |
| 4 | LGALS2 | LGALS2 Entrez, Source | lectin, galactoside-binding, soluble, 2 (galectin 2) | 95 | 0.672 | 0.3741 | Yes |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 107 | 0.646 | 0.4365 | Yes |
| 6 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 202 | 0.486 | 0.4770 | Yes |
| 7 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.5219 | Yes |
| 8 | KCNN2 | KCNN2 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 403 | 0.336 | 0.5410 | Yes |
| 9 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 405 | 0.336 | 0.5738 | Yes |
| 10 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 407 | 0.334 | 0.6063 | Yes |
| 11 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 565 | 0.265 | 0.6204 | Yes |
| 12 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 740 | 0.229 | 0.6297 | Yes |
| 13 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 799 | 0.213 | 0.6462 | Yes |
| 14 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 1095 | 0.171 | 0.6407 | No |
| 15 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 1736 | 0.120 | 0.6043 | No |
| 16 | TLR4 | TLR4 Entrez, Source | toll-like receptor 4 | 2232 | 0.098 | 0.5767 | No |
| 17 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 2345 | 0.094 | 0.5774 | No |
| 18 | CLTB | CLTB Entrez, Source | clathrin, light chain (Lcb) | 2459 | 0.089 | 0.5776 | No |
| 19 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3071 | 0.069 | 0.5384 | No |
| 20 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 3136 | 0.068 | 0.5402 | No |
| 21 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3202 | 0.066 | 0.5417 | No |
| 22 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 3344 | 0.061 | 0.5371 | No |
| 23 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 3438 | 0.060 | 0.5360 | No |
| 24 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 3449 | 0.059 | 0.5410 | No |
| 25 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.5445 | No |
| 26 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 3503 | 0.057 | 0.5484 | No |
| 27 | CYSLTR2 | CYSLTR2 Entrez, Source | cysteinyl leukotriene receptor 2 | 3517 | 0.057 | 0.5530 | No |
| 28 | KLK6 | KLK6 Entrez, Source | kallikrein 6 (neurosin, zyme) | 4060 | 0.043 | 0.5164 | No |
| 29 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4575 | 0.033 | 0.4809 | No |
| 30 | CAV3 | CAV3 Entrez, Source | caveolin 3 | 4995 | 0.024 | 0.4518 | No |
| 31 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5155 | 0.021 | 0.4419 | No |
| 32 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 5285 | 0.019 | 0.4340 | No |
| 33 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 5689 | 0.011 | 0.4048 | No |
| 34 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6181 | 0.001 | 0.3680 | No |
| 35 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 6479 | -0.003 | 0.3460 | No |
| 36 | CHST10 | CHST10 Entrez, Source | carbohydrate sulfotransferase 10 | 6568 | -0.005 | 0.3398 | No |
| 37 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 6591 | -0.005 | 0.3387 | No |
| 38 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6942 | -0.011 | 0.3135 | No |
| 39 | TRPV5 | TRPV5 Entrez, Source | transient receptor potential cation channel, subfamily V, member 5 | 7267 | -0.017 | 0.2908 | No |
| 40 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7323 | -0.018 | 0.2884 | No |
| 41 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 7528 | -0.022 | 0.2752 | No |
| 42 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 8233 | -0.036 | 0.2258 | No |
| 43 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 8298 | -0.037 | 0.2246 | No |
| 44 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 8369 | -0.039 | 0.2231 | No |
| 45 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | 0.2039 | No |
| 46 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 9259 | -0.057 | 0.1663 | No |
| 47 | MFNG | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 10295 | -0.084 | 0.0967 | No |
| 48 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | 0.0414 | No |
| 49 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 12217 | -0.173 | -0.0196 | No |
| 50 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 12797 | -0.241 | -0.0396 | No |
| 51 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 12892 | -0.265 | -0.0208 | No |
| 52 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12946 | -0.276 | 0.0022 | No |
| 53 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 12969 | -0.282 | 0.0281 | No |
