Details for gene set NETPATH_IL_4_PATHWAY

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	NETPATH_IL_4_PATHWAY_UP
Enrichment Score (ES)	0.49431282
Normalized Enrichment Score (NES)	1.8323927
Nominal p-value	0.0
FDR q-value	0.02176017
FWER p-Value	0.856

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	3	1.622	0.0765	Yes
2	ANXA1	ANXA1 Entrez, Source	annexin A1	25	0.995	0.1220	Yes
3	MAF	MAF Entrez, Source	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	31	0.935	0.1658	Yes
4	TIMP2	TIMP2 Entrez, Source	TIMP metallopeptidase inhibitor 2	49	0.810	0.2028	Yes
5	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	50	0.810	0.2411	Yes
6	CYP1A1	CYP1A1 Entrez, Source	cytochrome P450, family 1, subfamily A, polypeptide 1	75	0.697	0.2722	Yes
7	VCAM1	VCAM1 Entrez, Source	vascular cell adhesion molecule 1	183	0.515	0.2885	Yes
8	F13A1	F13A1 Entrez, Source	coagulation factor XIII, A1 polypeptide	186	0.510	0.3124	Yes
9	KLF4	KLF4 Entrez, Source	Kruppel-like factor 4 (gut)	255	0.437	0.3280	Yes
10	ARG1	ARG1 Entrez, Source	arginase, liver	307	0.397	0.3429	Yes
11	EGR2	EGR2 Entrez, Source	early growth response 2 (Krox-20 homolog, Drosophila)	312	0.390	0.3610	Yes
12	JAG1	JAG1 Entrez, Source	jagged 1 (Alagille syndrome)	318	0.386	0.3789	Yes
13	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	405	0.336	0.3883	Yes
14	FKBP5	FKBP5 Entrez, Source	FK506 binding protein 5	412	0.330	0.4034	Yes
15	CPT2	CPT2 Entrez, Source	carnitine palmitoyltransferase II	419	0.326	0.4184	Yes
16	BMP2	BMP2 Entrez, Source	bone morphogenetic protein 2	509	0.282	0.4250	Yes
17	LOX	LOX Entrez, Source	lysyl oxidase	558	0.267	0.4339	Yes
18	ABCD3	ABCD3 Entrez, Source	ATP-binding cassette, sub-family D (ALD), member 3	622	0.251	0.4411	Yes
19	GUCY1B3	GUCY1B3 Entrez, Source	guanylate cyclase 1, soluble, beta 3	744	0.228	0.4427	Yes
20	PSCD1	PSCD1 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)	789	0.217	0.4496	Yes
21	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	793	0.215	0.4595	Yes
22	PAWR	PAWR Entrez, Source	PRKC, apoptosis, WT1, regulator	899	0.196	0.4609	Yes
23	F3	F3 Entrez, Source	coagulation factor III (thromboplastin, tissue factor)	956	0.188	0.4655	Yes
24	FBN1	FBN1 Entrez, Source	fibrillin 1	968	0.187	0.4735	Yes
25	TFPI	TFPI Entrez, Source	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	1052	0.177	0.4755	Yes
26	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	1070	0.174	0.4825	Yes
27	HS3ST1	HS3ST1 Entrez, Source	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	1203	0.161	0.4801	Yes
28	FN1	FN1 Entrez, Source	fibronectin 1	1246	0.156	0.4843	Yes
29	SLC39A8	SLC39A8 Entrez, Source	solute carrier family 39 (zinc transporter), member 8	1256	0.156	0.4910	Yes
30	PTGER2	PTGER2 Entrez, Source	prostaglandin E receptor 2 (subtype EP2), 53kDa	1419	0.141	0.4854	Yes
31	TIMP3	TIMP3 Entrez, Source	TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)	1445	0.139	0.4901	Yes
32	HPCAL1	HPCAL1 Entrez, Source	hippocalcin-like 1	1490	0.136	0.4932	Yes
33	ITGAM	ITGAM Entrez, Source	integrin, alpha M (complement component 3 receptor 3 subunit)	1608	0.128	0.4904	Yes
34	SLC38A1	SLC38A1 Entrez, Source	solute carrier family 38, member 1	1676	0.124	0.4911	Yes
35	SULF1	SULF1 Entrez, Source	sulfatase 1	1735	0.120	0.4924	Yes
36	BMP4	BMP4 Entrez, Source	bone morphogenetic protein 4	1870	0.113	0.4877	Yes
37	GCNT1	GCNT1 Entrez, Source	glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)	1898	0.112	0.4909	Yes
38	TMOD1	TMOD1 Entrez, Source	tropomodulin 1	2135	0.102	0.4779	Yes
39	MAOA	MAOA Entrez, Source	monoamine oxidase A	2159	0.101	0.4809	Yes
40	GATA6	GATA6 Entrez, Source	GATA binding protein 6	2206	0.099	0.4821	Yes
41	ALOX15	ALOX15 Entrez, Source	arachidonate 15-lipoxygenase	2217	0.099	0.4860	Yes
42	IL2RB	IL2RB Entrez, Source	interleukin 2 receptor, beta	2225	0.098	0.4901	Yes
43	TLR4	TLR4 Entrez, Source	toll-like receptor 4	2232	0.098	0.4943	Yes
44	IL10RA	IL10RA Entrez, Source	interleukin 10 receptor, alpha	2351	0.093	0.4898	No
45	AGC1	AGC1 Entrez, Source	aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)	2489	0.088	0.4836	No
46	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	2490	0.088	0.4878	No
47	PDZK1IP1	PDZK1IP1 Entrez, Source	PDZK1 interacting protein 1	2512	0.087	0.4903	No
48	SAMSN1	SAMSN1 Entrez, Source	SAM domain, SH3 domain and nuclear localisation signals, 1	2606	0.083	0.4872	No
49	GAS6	GAS6 Entrez, Source	growth arrest-specific 6	3043	0.070	0.4575	No
50	SCGB3A1	SCGB3A1 Entrez, Source	secretoglobin, family 3A, member 1	3058	0.069	0.4597	No
51	SPINT2	SPINT2 Entrez, Source	serine peptidase inhibitor, Kunitz type, 2	3064	0.069	0.4626	No
52	FGL2	FGL2 Entrez, Source	fibrinogen-like 2	3128	0.068	0.4611	No
53	CART1	CART1 Entrez, Source	cartilage paired-class homeoprotein 1	3328	0.062	0.4489	No
54	IL10	IL10 Entrez, Source	interleukin 10	3439	0.059	0.4434	No
55	ST6GAL1	ST6GAL1 Entrez, Source	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	3452	0.059	0.4453	No
56	ACTN1	ACTN1 Entrez, Source	actinin, alpha 1	3460	0.059	0.4475	No
57	ID3	ID3 Entrez, Source	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	3479	0.058	0.4489	No
58	ST8SIA1	ST8SIA1 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	3554	0.056	0.4460	No
59	UBL3	UBL3 Entrez, Source	ubiquitin-like 3	3635	0.054	0.4425	No
60	ALDH1A2	ALDH1A2 Entrez, Source	aldehyde dehydrogenase 1 family, member A2	3710	0.052	0.4393	No
61	CXCR4	CXCR4 Entrez, Source	chemokine (C-X-C motif) receptor 4	3767	0.051	0.4375	No
62	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3795	0.050	0.4378	No
63	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	3822	0.050	0.4382	No
64	CDC25A	CDC25A Entrez, Source	cell division cycle 25A	4102	0.042	0.4190	No
65	BCL2	BCL2 Entrez, Source	B-cell CLL/lymphoma 2	4187	0.040	0.4146	No
66	ELL2	ELL2 Entrez, Source	elongation factor, RNA polymerase II, 2	4354	0.037	0.4037	No
67	CTSC	CTSC Entrez, Source	cathepsin C	4468	0.035	0.3968	No
68	CASP3	CASP3 Entrez, Source	caspase 3, apoptosis-related cysteine peptidase	4606	0.032	0.3879	No
69	IGHE	IGHE Entrez, Source	immunoglobulin heavy constant epsilon	4757	0.029	0.3779	No
70	NFKB1	NFKB1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	4778	0.028	0.3778	No
71	ATXN1	ATXN1 Entrez, Source	ataxin 1	4845	0.027	0.3741	No
72	IFNG	IFNG Entrez, Source	interferon, gamma	4856	0.027	0.3746	No
73	SATB1	SATB1 Entrez, Source	special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)	5070	0.023	0.3595	No
74	IL13RA2	IL13RA2 Entrez, Source	interleukin 13 receptor, alpha 2	5146	0.021	0.3549	No
75	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	5285	0.019	0.3453	No
76	XCL1	XCL1 Entrez, Source	chemokine (C motif) ligand 1	5671	0.012	0.3167	No
77	RELA	RELA Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	5892	0.007	0.3004	No
78	KCNK3	KCNK3 Entrez, Source	potassium channel, subfamily K, member 3	5898	0.007	0.3003	No
79	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	6062	0.004	0.2882	No
80	VDR	VDR Entrez, Source	vitamin D (1,25- dihydroxyvitamin D3) receptor	6077	0.004	0.2873	No
81	GATA3	GATA3 Entrez, Source	GATA binding protein 3	6151	0.002	0.2819	No
82	POU4F1	POU4F1 Entrez, Source	POU domain, class 4, transcription factor 1	6349	-0.001	0.2670	No
83	CHST10	CHST10 Entrez, Source	carbohydrate sulfotransferase 10	6568	-0.005	0.2507	No
84	JUN	JUN Entrez, Source	jun oncogene	6649	-0.006	0.2450	No
85	IL13	IL13 Entrez, Source	interleukin 13	6740	-0.008	0.2385	No
86	CCL22	CCL22 Entrez, Source	chemokine (C-C motif) ligand 22	7142	-0.015	0.2089	No
87	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	7236	-0.017	0.2026	No
88	CTSL	CTSL Entrez, Source	cathepsin L	7390	-0.020	0.1919	No
89	GNAI1	GNAI1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	7518	-0.022	0.1834	No
90	RBMS1	RBMS1 Entrez, Source	RNA binding motif, single stranded interacting protein 1	7645	-0.024	0.1750	No
91	GJA5	GJA5 Entrez, Source	gap junction protein, alpha 5, 40kDa (connexin 40)	7650	-0.025	0.1758	No
92	CD86	CD86 Entrez, Source	CD86 molecule	7686	-0.025	0.1744	No
93	INHBA	INHBA Entrez, Source	inhibin, beta A (activin A, activin AB alpha polypeptide)	7768	-0.027	0.1695	No
94	SLC11A2	SLC11A2 Entrez, Source	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	7794	-0.027	0.1689	No
95	CSPG2	CSPG2 Entrez, Source	chondroitin sulfate proteoglycan 2 (versican)	7897	-0.029	0.1625	No
96	NKG7	NKG7 Entrez, Source	natural killer cell group 7 sequence	7948	-0.030	0.1602	No
97	RIPK2	RIPK2 Entrez, Source	receptor-interacting serine-threonine kinase 2	8400	-0.039	0.1279	No
98	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	8582	-0.043	0.1162	No
99	TFEC	TFEC Entrez, Source	transcription factor EC	8607	-0.044	0.1165	No
100	CREM	CREM Entrez, Source	cAMP responsive element modulator	8985	-0.051	0.0904	No
101	LRRN3	LRRN3 Entrez, Source	leucine rich repeat neuronal 3	9072	-0.053	0.0864	No
102	AHR	AHR Entrez, Source	aryl hydrocarbon receptor	9118	-0.054	0.0855	No
103	IGF1	IGF1 Entrez, Source	insulin-like growth factor 1 (somatomedin C)	9134	-0.055	0.0870	No
104	ENPP1	ENPP1 Entrez, Source	ectonucleotide pyrophosphatase/phosphodiesterase 1	9193	-0.056	0.0852	No
105	IL4R	IL4R Entrez, Source	interleukin 4 receptor	9312	-0.058	0.0791	No
106	RASA2	RASA2 Entrez, Source	RAS p21 protein activator 2	9408	-0.061	0.0747	No
107	HSPA8	HSPA8 Entrez, Source	heat shock 70kDa protein 8	9449	-0.062	0.0746	No
108	GZMB	GZMB Entrez, Source	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	9634	-0.066	0.0638	No
109	SOCS3	SOCS3 Entrez, Source	suppressor of cytokine signaling 3	9839	-0.072	0.0518	No
110	DMD	DMD Entrez, Source	dystrophin (muscular dystrophy, Duchenne and Becker types)	9896	-0.074	0.0510	No
111	LIFR	LIFR Entrez, Source	leukemia inhibitory factor receptor alpha	9964	-0.075	0.0495	No
112	STK17B	STK17B Entrez, Source	serine/threonine kinase 17b (apoptosis-inducing)	9987	-0.076	0.0515	No
113	CH25H	CH25H Entrez, Source	cholesterol 25-hydroxylase	10018	-0.077	0.0528	No
114	RASGRP1	RASGRP1 Entrez, Source	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	10260	-0.083	0.0385	No
115	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	10321	-0.085	0.0380	No
116	RDX	RDX Entrez, Source	radixin	10400	-0.087	0.0362	No
117	EDNRA	EDNRA Entrez, Source	endothelin receptor type A	10591	-0.093	0.0263	No
118	SELE	SELE Entrez, Source	selectin E (endothelial adhesion molecule 1)	10650	-0.095	0.0264	No
119	NFIL3	NFIL3 Entrez, Source	nuclear factor, interleukin 3 regulated	10654	-0.095	0.0307	No
120	CA2	CA2 Entrez, Source	carbonic anhydrase II	10759	-0.099	0.0275	No
121	BCL2L11	BCL2L11 Entrez, Source	BCL2-like 11 (apoptosis facilitator)	11005	-0.108	0.0140	No
122	EEF1A2	EEF1A2 Entrez, Source	eukaryotic translation elongation factor 1 alpha 2	11120	-0.113	0.0108	No
123	TOP2A	TOP2A Entrez, Source	topoisomerase (DNA) II alpha 170kDa	11410	-0.125	-0.0052	No
124	MET	MET Entrez, Source	met proto-oncogene (hepatocyte growth factor receptor)	11573	-0.132	-0.0112	No
125	IL1RN	IL1RN Entrez, Source	interleukin 1 receptor antagonist	11709	-0.139	-0.0149	No
126	CYP2E1	CYP2E1 Entrez, Source	cytochrome P450, family 2, subfamily E, polypeptide 1	11911	-0.151	-0.0230	No
127	PMCH	PMCH Entrez, Source	pro-melanin-concentrating hormone	12026	-0.159	-0.0241	No
128	HSPB8	HSPB8 Entrez, Source	heat shock 22kDa protein 8	12237	-0.175	-0.0317	No
129	MYC	MYC Entrez, Source	v-myc myelocytomatosis viral oncogene homolog (avian)	12249	-0.175	-0.0243	No
130	IL13RA1	IL13RA1 Entrez, Source	interleukin 13 receptor, alpha 1	12296	-0.179	-0.0193	No
131	SLC22A4	SLC22A4 Entrez, Source	solute carrier family 22 (organic cation transporter), member 4	12628	-0.215	-0.0342	No
132	DNAJC3	DNAJC3 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 3	12713	-0.226	-0.0299	No
133	MCM7	MCM7 Entrez, Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	13101	-0.328	-0.0437	No
134	CASP2	CASP2 Entrez, Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	13151	-0.360	-0.0304	No
135	EDG1	EDG1 Entrez, Source	endothelial differentiation, sphingolipid G-protein-coupled receptor, 1	13191	-0.391	-0.0148	No
136	MCM6	MCM6 Entrez, Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	13288	-0.553	0.0041	No