Details for gene set NING_COPD

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in class	double_gel_8d
GeneSet	NING_COPD_UP
Enrichment Score (ES)	0.4862242
Normalized Enrichment Score (NES)	1.7086638
Nominal p-value	0.0
FDR q-value	0.05257883
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	3	1.622	0.1267	Yes
2	CTGF	CTGF Entrez, Source	connective tissue growth factor	37	0.888	0.1936	Yes
3	ACTA1	ACTA1 Entrez, Source	actin, alpha 1, skeletal muscle	60	0.762	0.2516	Yes
4	LGALS1	LGALS1 Entrez, Source	lectin, galactoside-binding, soluble, 1 (galectin 1)	82	0.687	0.3037	Yes
5	COL4A1	COL4A1 Entrez, Source	collagen, type IV, alpha 1	89	0.680	0.3564	Yes
6	CDC42EP2	CDC42EP2 Entrez, Source	CDC42 effector protein (Rho GTPase binding) 2	399	0.337	0.3595	Yes
7	TMSB10	TMSB10 Entrez, Source	thymosin, beta 10	476	0.294	0.3767	Yes
8	ALCAM	ALCAM Entrez, Source	activated leukocyte cell adhesion molecule	507	0.282	0.3966	Yes
9	RAMP3	RAMP3 Entrez, Source	receptor (calcitonin) activity modifying protein 3	518	0.280	0.4177	Yes
10	RARRES2	RARRES2 Entrez, Source	retinoic acid receptor responder (tazarotene induced) 2	544	0.271	0.4370	Yes
11	CX3CL1	CX3CL1 Entrez, Source	chemokine (C-X3-C motif) ligand 1	796	0.215	0.4348	Yes
12	TLE2	TLE2 Entrez, Source	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	1029	0.179	0.4313	Yes
13	CYR61	CYR61 Entrez, Source	cysteine-rich, angiogenic inducer, 61	1062	0.175	0.4425	Yes
14	FEZ2	FEZ2 Entrez, Source	fasciculation and elongation protein zeta 2 (zygin II)	1075	0.173	0.4552	Yes
15	COL18A1	COL18A1 Entrez, Source	collagen, type XVIII, alpha 1	1103	0.170	0.4665	Yes
16	DPYSL3	DPYSL3 Entrez, Source	dihydropyrimidinase-like 3	1163	0.164	0.4749	Yes
17	WFS1	WFS1 Entrez, Source	Wolfram syndrome 1 (wolframin)	1182	0.163	0.4862	Yes
18	MAF1	MAF1 Entrez, Source	MAF1 homolog (S. cerevisiae)	1532	0.133	0.4703	No
19	EGR1	EGR1 Entrez, Source	early growth response 1	1666	0.124	0.4699	No
20	VAMP8	VAMP8 Entrez, Source	vesicle-associated membrane protein 8 (endobrevin)	1782	0.118	0.4705	No
21	TGFB1	TGFB1 Entrez, Source	transforming growth factor, beta 1 (Camurati-Engelmann disease)	2076	0.105	0.4565	No
22	FASN	FASN Entrez, Source	fatty acid synthase	2099	0.104	0.4630	No
23	VWF	VWF Entrez, Source	von Willebrand factor	2400	0.092	0.4475	No
24	ATP5B	ATP5B Entrez, Source	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	2564	0.085	0.4419	No
25	APOE	APOE Entrez, Source	apolipoprotein E	2619	0.083	0.4443	No
26	GPX4	GPX4 Entrez, Source	glutathione peroxidase 4 (phospholipid hydroperoxidase)	2713	0.080	0.4435	No
27	INPP1	INPP1 Entrez, Source	inositol polyphosphate-1-phosphatase	2901	0.074	0.4352	No
28	PNRC1	PNRC1 Entrez, Source	proline-rich nuclear receptor coactivator 1	2915	0.074	0.4400	No
29	NBL1	NBL1 Entrez, Source	neuroblastoma, suppression of tumorigenicity 1	2982	0.072	0.4406	No
30	MAPKAPK3	MAPKAPK3 Entrez, Source	mitogen-activated protein kinase-activated protein kinase 3	3069	0.069	0.4395	No
31	CSK	CSK Entrez, Source	c-src tyrosine kinase	3403	0.060	0.4191	No
32	CTSF	CTSF Entrez, Source	cathepsin F	3540	0.056	0.4133	No
33	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	3822	0.050	0.3959	No
34	GTF2I	GTF2I Entrez, Source	general transcription factor II, i	3859	0.048	0.3970	No
35	TGFBI	TGFBI Entrez, Source	transforming growth factor, beta-induced, 68kDa	4125	0.042	0.3803	No
36	G3BP	G3BP Entrez, Source	-	4201	0.039	0.3777	No
37	CAPNS1	CAPNS1 Entrez, Source	calpain, small subunit 1	4212	0.039	0.3800	No
38	MTCH1	MTCH1 Entrez, Source	mitochondrial carrier homolog 1 (C. elegans)	4213	0.039	0.3831	No
39	IGFBP4	IGFBP4 Entrez, Source	insulin-like growth factor binding protein 4	4578	0.032	0.3582	No
40	TFF3	TFF3 Entrez, Source	trefoil factor 3 (intestinal)	4594	0.032	0.3595	No
41	A2M	A2M Entrez, Source	alpha-2-macroglobulin	4951	0.025	0.3346	No
42	CYBRD1	CYBRD1 Entrez, Source	cytochrome b reductase 1	5173	0.021	0.3196	No
43	CPA3	CPA3 Entrez, Source	carboxypeptidase A3 (mast cell)	5582	0.013	0.2898	No
44	PTP4A1	PTP4A1 Entrez, Source	protein tyrosine phosphatase type IVA, member 1	5658	0.012	0.2851	No
45	ATP5D	ATP5D Entrez, Source	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	5816	0.009	0.2739	No
46	LAPTM5	LAPTM5 Entrez, Source	lysosomal associated multispanning membrane protein 5	5827	0.009	0.2738	No
47	ARCN1	ARCN1 Entrez, Source	archain 1	5911	0.007	0.2681	No
48	NDUFA5	NDUFA5 Entrez, Source	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa	6009	0.005	0.2612	No
49	EGFL7	EGFL7 Entrez, Source	EGF-like-domain, multiple 7	6196	0.001	0.2472	No
50	PNMT	PNMT Entrez, Source	phenylethanolamine N-methyltransferase	6269	0.000	0.2418	No
51	NCKAP1	NCKAP1 Entrez, Source	NCK-associated protein 1	6284	0.000	0.2408	No
52	DVL1	DVL1 Entrez, Source	dishevelled, dsh homolog 1 (Drosophila)	6668	-0.007	0.2124	No
53	IL1R1	IL1R1 Entrez, Source	interleukin 1 receptor, type I	6718	-0.007	0.2093	No
54	MSLN	MSLN Entrez, Source	mesothelin	6799	-0.009	0.2039	No
55	HIF3A	HIF3A Entrez, Source	hypoxia inducible factor 3, alpha subunit	6901	-0.011	0.1971	No
56	CDC2L1	CDC2L1 Entrez, Source	cell division cycle 2-like 1 (PITSLRE proteins)	7029	-0.013	0.1886	No
57	DCN	DCN Entrez, Source	decorin	7217	-0.016	0.1757	No
58	NPC2	NPC2 Entrez, Source	Niemann-Pick disease, type C2	7253	-0.017	0.1744	No
59	ITPKB	ITPKB Entrez, Source	inositol 1,4,5-trisphosphate 3-kinase B	7323	-0.018	0.1706	No
60	RPLP1	RPLP1 Entrez, Source	ribosomal protein, large, P1	7767	-0.027	0.1393	No
61	CLDN5	CLDN5 Entrez, Source	claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)	8120	-0.034	0.1154	No
62	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	8582	-0.043	0.0839	No
63	CDKN1A	CDKN1A Entrez, Source	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	8685	-0.045	0.0798	No
64	BCAP31	BCAP31 Entrez, Source	B-cell receptor-associated protein 31	8715	-0.046	0.0812	No
65	RPS15	RPS15 Entrez, Source	ribosomal protein S15	9166	-0.055	0.0515	No
66	ACTN4	ACTN4 Entrez, Source	actinin, alpha 4	9335	-0.059	0.0435	No
67	BLVRA	BLVRA Entrez, Source	biliverdin reductase A	9379	-0.060	0.0449	No
68	H3F3B	H3F3B Entrez, Source	H3 histone, family 3B (H3.3B)	9390	-0.060	0.0489	No
69	RPL32	RPL32 Entrez, Source	ribosomal protein L32	9393	-0.060	0.0534	No
70	GRINA	GRINA Entrez, Source	glutamate receptor, ionotropic, N-methyl D-asparate-associated protein 1 (glutamate binding)	9530	-0.063	0.0481	No
71	FGG	FGG Entrez, Source	fibrinogen gamma chain	9841	-0.072	0.0304	No
72	SSRP1	SSRP1 Entrez, Source	structure specific recognition protein 1	9875	-0.073	0.0336	No
73	PTBP1	PTBP1 Entrez, Source	polypyrimidine tract binding protein 1	10089	-0.079	0.0237	No
74	RPL4	RPL4 Entrez, Source	ribosomal protein L4	10242	-0.083	0.0187	No
75	RPL13	RPL13 Entrez, Source	ribosomal protein L13	10259	-0.083	0.0240	No
76	RPS23	RPS23 Entrez, Source	ribosomal protein S23	10436	-0.088	0.0176	No
77	C1R	C1R Entrez, Source	complement component 1, r subcomponent	10455	-0.089	0.0233	No
78	CALM1	CALM1 Entrez, Source	calmodulin 1 (phosphorylase kinase, delta)	10674	-0.096	0.0143	No
79	EIF4A1	EIF4A1 Entrez, Source	eukaryotic translation initiation factor 4A, isoform 1	11080	-0.111	-0.0075	No
80	RABGGTB	RABGGTB Entrez, Source	Rab geranylgeranyltransferase, beta subunit	11200	-0.116	-0.0074	No
81	DDX52	DDX52 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	11297	-0.120	-0.0053	No
82	EPRS	EPRS Entrez, Source	glutamyl-prolyl-tRNA synthetase	11364	-0.123	-0.0006	No
83	RPL22	RPL22 Entrez, Source	ribosomal protein L22	11388	-0.124	0.0073	No
84	IGJ	IGJ Entrez, Source	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	11506	-0.129	0.0086	No
85	RPS3	RPS3 Entrez, Source	ribosomal protein S3	11507	-0.129	0.0187	No
86	CAPN3	CAPN3 Entrez, Source	calpain 3, (p94)	11560	-0.132	0.0251	No
87	RPL14	RPL14 Entrez, Source	ribosomal protein L14	11799	-0.144	0.0184	No
88	SFRS10	SFRS10 Entrez, Source	splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)	12334	-0.182	-0.0076	No
89	SDC1	SDC1 Entrez, Source	syndecan 1	12438	-0.192	-0.0004	No
90	ILF3	ILF3 Entrez, Source	interleukin enhancer binding factor 3, 90kDa	12940	-0.274	-0.0168	No
91	MAT2A	MAT2A Entrez, Source	methionine adenosyltransferase II, alpha	13299	-0.601	0.0032	No