Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NITROGEN_COMPOUND_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.7143594 |
| Normalized Enrichment Score (NES) | 1.9815981 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0066354033 |
| FWER p-Value | 0.205 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.1445 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 138 | 0.591 | 0.2674 | Yes |
| 3 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 232 | 0.457 | 0.3590 | Yes |
| 4 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 258 | 0.431 | 0.4500 | Yes |
| 5 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 276 | 0.416 | 0.5384 | Yes |
| 6 | ARG1 | ARG1 Entrez, Source | arginase, liver | 307 | 0.397 | 0.6217 | Yes |
| 7 | MCCC2 | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 663 | 0.243 | 0.6474 | Yes |
| 8 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 869 | 0.200 | 0.6751 | Yes |
| 9 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 906 | 0.195 | 0.7144 | Yes |
| 10 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 1832 | 0.115 | 0.6697 | No |
| 11 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 1969 | 0.109 | 0.6830 | No |
| 12 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 2090 | 0.104 | 0.6964 | No |
| 13 | AMT | AMT Entrez, Source | aminomethyltransferase | 2221 | 0.098 | 0.7079 | No |
| 14 | COLQ | COLQ Entrez, Source | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 2670 | 0.081 | 0.6917 | No |
| 15 | MPST | MPST Entrez, Source | mercaptopyruvate sulfurtransferase | 3621 | 0.054 | 0.6321 | No |
| 16 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 3887 | 0.048 | 0.6225 | No |
| 17 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 4297 | 0.038 | 0.5999 | No |
| 18 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 6099 | 0.003 | 0.4654 | No |
| 19 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6481 | -0.003 | 0.4375 | No |
| 20 | ASL | ASL Entrez, Source | argininosuccinate lyase | 6773 | -0.008 | 0.4174 | No |
| 21 | DHPS | DHPS Entrez, Source | deoxyhypusine synthase | 7301 | -0.018 | 0.3817 | No |
| 22 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 9270 | -0.057 | 0.2463 | No |
| 23 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9641 | -0.066 | 0.2329 | No |
| 24 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 10558 | -0.092 | 0.1839 | No |
| 25 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11204 | -0.116 | 0.1605 | No |
