Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | NUCLEAR_ENVELOPE |
| Enrichment Score (ES) | -0.50989914 |
| Normalized Enrichment Score (NES) | -1.6932749 |
| Nominal p-value | 0.0022172949 |
| FDR q-value | 0.10312452 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRICKLE1 | PRICKLE1 Entrez, Source | prickle homolog 1 (Drosophila) | 927 | 0.191 | -0.0291 | No |
| 2 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 1210 | 0.160 | -0.0162 | No |
| 3 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 1507 | 0.134 | -0.0098 | No |
| 4 | NUP50 | NUP50 Entrez, Source | nucleoporin 50kDa | 2190 | 0.100 | -0.0399 | No |
| 5 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 2474 | 0.089 | -0.0422 | No |
| 6 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4187 | 0.040 | -0.1625 | No |
| 7 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.1573 | No |
| 8 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 4311 | 0.037 | -0.1555 | No |
| 9 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 4726 | 0.030 | -0.1803 | No |
| 10 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5474 | 0.015 | -0.2332 | No |
| 11 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 5642 | 0.012 | -0.2432 | No |
| 12 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 5728 | 0.010 | -0.2474 | No |
| 13 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 5729 | 0.010 | -0.2452 | No |
| 14 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 6115 | 0.003 | -0.2735 | No |
| 15 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6268 | 0.000 | -0.2849 | No |
| 16 | NRM | NRM Entrez, Source | nurim (nuclear envelope membrane protein) | 6596 | -0.006 | -0.3083 | No |
| 17 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7190 | -0.016 | -0.3495 | No |
| 18 | SREBF1 | SREBF1 Entrez, Source | sterol regulatory element binding transcription factor 1 | 7713 | -0.026 | -0.3834 | No |
| 19 | EMD | EMD Entrez, Source | emerin (Emery-Dreifuss muscular dystrophy) | 7893 | -0.029 | -0.3906 | No |
| 20 | KPNA3 | KPNA3 Entrez, Source | karyopherin alpha 3 (importin alpha 4) | 8218 | -0.036 | -0.4074 | No |
| 21 | GUCY2D | GUCY2D Entrez, Source | guanylate cyclase 2D, membrane (retina-specific) | 9331 | -0.059 | -0.4785 | No |
| 22 | DULLARD | DULLARD Entrez, Source | dullard homolog (Xenopus laevis) | 9749 | -0.069 | -0.4952 | Yes |
| 23 | GRINL1A | GRINL1A Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A | 9811 | -0.071 | -0.4846 | Yes |
| 24 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 9855 | -0.073 | -0.4725 | Yes |
| 25 | MATR3 | MATR3 Entrez, Source | matrin 3 | 10114 | -0.079 | -0.4749 | Yes |
| 26 | LBR | LBR Entrez, Source | lamin B receptor | 10137 | -0.080 | -0.4596 | Yes |
| 27 | SP140 | SP140 Entrez, Source | SP140 nuclear body protein | 10141 | -0.080 | -0.4428 | Yes |
| 28 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 10142 | -0.080 | -0.4257 | Yes |
| 29 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 10178 | -0.081 | -0.4111 | Yes |
| 30 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10524 | -0.091 | -0.4177 | Yes |
| 31 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10704 | -0.097 | -0.4105 | Yes |
| 32 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 10771 | -0.100 | -0.3942 | Yes |
| 33 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 11085 | -0.111 | -0.3941 | Yes |
| 34 | XPO7 | XPO7 Entrez, Source | exportin 7 | 11138 | -0.114 | -0.3738 | Yes |
| 35 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 11241 | -0.118 | -0.3564 | Yes |
| 36 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 11328 | -0.121 | -0.3370 | Yes |
| 37 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 11453 | -0.127 | -0.3193 | Yes |
| 38 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11546 | -0.131 | -0.2983 | Yes |
| 39 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 11576 | -0.132 | -0.2723 | Yes |
| 40 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 11618 | -0.135 | -0.2468 | Yes |
| 41 | SENP2 | SENP2 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 2 | 11664 | -0.136 | -0.2211 | Yes |
| 42 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 11760 | -0.142 | -0.1980 | Yes |
| 43 | KPNA1 | KPNA1 Entrez, Source | karyopherin alpha 1 (importin alpha 5) | 11791 | -0.144 | -0.1697 | Yes |
| 44 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 11830 | -0.146 | -0.1414 | Yes |
| 45 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11979 | -0.156 | -0.1193 | Yes |
| 46 | NUP88 | NUP88 Entrez, Source | nucleoporin 88kDa | 12448 | -0.193 | -0.1134 | Yes |
| 47 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12477 | -0.196 | -0.0738 | Yes |
| 48 | NUP54 | NUP54 Entrez, Source | nucleoporin 54kDa | 13079 | -0.318 | -0.0513 | Yes |
| 49 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 13111 | -0.334 | 0.0174 | Yes |
