Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetNUCLEAR_LUMEN
Enrichment Score (ES)-0.46751776
Normalized Enrichment Score (NES)-1.9096102
Nominal p-value0.0
FDR q-value0.018829076
FWER p-Value0.368
Table: GSEA Results Summary



Fig 1: Enrichment plot: NUCLEAR_LUMEN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NOL3NOL3
Entrez,  Source
nucleolar protein 3 (apoptosis repressor with CARD domain)2370.4540.0113No
2LMO4LMO4
Entrez,  Source
LIM domain only 48240.209-0.0197No
3PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 210470.177-0.0251No
4PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha10660.174-0.0152No
5CIB1CIB1
Entrez,  Source
calcium and integrin binding 1 (calmyrin)16050.128-0.0478No
6MEN1MEN1
Entrez,  Source
multiple endocrine neoplasia I17050.122-0.0474No
7SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 218010.117-0.0471No
8HDAC7AHDAC7A
Entrez,  Source
histone deacetylase 7A21330.102-0.0656No
9RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)21620.101-0.0612No
10CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)21830.100-0.0563No
11NAP1L2NAP1L2
Entrez,  Source
nucleosome assembly protein 1-like 222680.097-0.0564No
12PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 124740.089-0.0662No
13PPARGC1BPPARGC1B
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, beta27820.077-0.0845No
14XRCC6XRCC6
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)30800.069-0.1026No
15NAP1L1NAP1L1
Entrez,  Source
nucleosome assembly protein 1-like 131100.068-0.1004No
16NFYBNFYB
Entrez,  Source
nuclear transcription factor Y, beta33420.061-0.1140No
17DEDDDEDD
Entrez,  Source
death effector domain containing35130.057-0.1232No
18HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)37150.052-0.1351No
19MCRS1MCRS1
Entrez,  Source
microspherule protein 137440.051-0.1339No
20PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin38620.048-0.1397No
21HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 138720.048-0.1373No
22EXOSC9EXOSC9
Entrez,  Source
exosome component 940780.043-0.1501No
23NCR1NCR1
Entrez,  Source
natural cytotoxicity triggering receptor 140970.042-0.1487No
24PTF1APTF1A
Entrez,  Source
pancreas specific transcription factor, 1a41390.041-0.1491No
25REXO4REXO4
Entrez,  Source
REX4, RNA exonuclease 4 homolog (S. cerevisiae)41690.040-0.1487No
26HDAC3HDAC3
Entrez,  Source
histone deacetylase 342410.039-0.1516No
27NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor43110.037-0.1545No
28GEMIN6GEMIN6
Entrez,  Source
gem (nuclear organelle) associated protein 643460.037-0.1547No
29ELL2ELL2
Entrez,  Source
elongation factor, RNA polymerase II, 243540.037-0.1528No
30CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)46100.032-0.1701No
31SC65SC65
Entrez,  Source
-47190.030-0.1764No
32ATXN1ATXN1
Entrez,  Source
ataxin 148450.027-0.1841No
33NAP1L4NAP1L4
Entrez,  Source
nucleosome assembly protein 1-like 450890.022-0.2011No
34TBPTBP
Entrez,  Source
TATA box binding protein51400.021-0.2035No
35IKBKAPIKBKAP
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein52260.020-0.2087No
36EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 153060.019-0.2135No
37TAF9TAF9
Entrez,  Source
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa55870.013-0.2339No
38CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)57380.010-0.2446No
39NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 2157760.009-0.2468No
40ACTBACTB
Entrez,  Source
actin, beta57880.009-0.2470No
41SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)58850.007-0.2538No
42RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)58920.007-0.2538No
43DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 960820.004-0.2679No
44SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)62130.001-0.2777No
45FGF18FGF18
Entrez,  Source
fibroblast growth factor 1862460.001-0.2801No
46NUP98NUP98
Entrez,  Source
nucleoporin 98kDa62680.000-0.2817No
47KLHL7KLHL7
Entrez,  Source
kelch-like 7 (Drosophila)62700.000-0.2817No
48GTF3C2GTF3C2
Entrez,  Source
general transcription factor IIIC, polypeptide 2, beta 110kDa6321-0.000-0.2855No
49ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 166337-0.001-0.2866No
50CPSF3CPSF3
Entrez,  Source
cleavage and polyadenylation specific factor 3, 73kDa6401-0.002-0.2913No
51SMARCD2SMARCD2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 26556-0.005-0.3026No
52INTS6INTS6
Entrez,  Source
integrator complex subunit 66560-0.005-0.3026No
53TAF6TAF6
Entrez,  Source
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa6603-0.006-0.3054No
54NFYCNFYC
Entrez,  Source
nuclear transcription factor Y, gamma6617-0.006-0.3060No
55RTCD1RTCD1
Entrez,  Source
RNA terminal phosphate cyclase domain 16731-0.008-0.3141No
56NKX2-5NKX2-5
Entrez,  Source
NK2 transcription factor related, locus 5 (Drosophila)6915-0.011-0.3273No
57PNMA1PNMA1
Entrez,  Source
paraneoplastic antigen MA16990-0.012-0.3321No
58SMARCB1SMARCB1
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 17003-0.012-0.3322No
59TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I7017-0.013-0.3324No
60PRM2PRM2
Entrez,  Source
protamine 27037-0.013-0.3330No
61OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase7089-0.014-0.3360No
62NFYANFYA
Entrez,  Source
nuclear transcription factor Y, alpha7202-0.016-0.3434No
63ZNF148ZNF148
Entrez,  Source
zinc finger protein 1487364-0.019-0.3544No
64GATAD2AGATAD2A
Entrez,  Source
GATA zinc finger domain containing 2A7397-0.020-0.3556No
65FOXE3FOXE3
Entrez,  Source
forkhead box E37406-0.020-0.3549No
66TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa7434-0.020-0.3556No
67PHBPHB
Entrez,  Source
prohibitin7736-0.026-0.3768No
68GCM1GCM1
Entrez,  Source
glial cells missing homolog 1 (Drosophila)7750-0.026-0.3761No
69CHAF1BCHAF1B
Entrez,  Source
chromatin assembly factor 1, subunit B (p60)7839-0.028-0.3809No
70COILCOIL
Entrez,  Source
coilin7869-0.029-0.3813No
71SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)8001-0.031-0.3892No
72KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)8037-0.032-0.3898No
73HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa8212-0.035-0.4007No
74SMARCA4SMARCA4
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 48251-0.036-0.4013No
75ATXN3ATXN3
Entrez,  Source
ataxin 38313-0.038-0.4035No
76UBE2IUBE2I
Entrez,  Source
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)8446-0.040-0.4109No
77SLU7SLU7
Entrez,  Source
-8593-0.043-0.4192No
78SMARCD3SMARCD3
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 38627-0.044-0.4188No
79HDAC5HDAC5
Entrez,  Source
histone deacetylase 58654-0.044-0.4179No
80GIT2GIT2
Entrez,  Source
G protein-coupled receptor kinase interactor 28964-0.051-0.4381No
81SAP18SAP18
Entrez,  Source
Sin3A-associated protein, 18kDa9025-0.052-0.4393No
82ASNA1ASNA1
Entrez,  Source
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)9112-0.054-0.4423No
83THRAP3THRAP3
Entrez,  Source
thyroid hormone receptor associated protein 39349-0.059-0.4564No
84RPL3RPL3
Entrez,  Source
ribosomal protein L39460-0.062-0.4607No
85NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)9513-0.063-0.4606No
86SYMPKSYMPK
Entrez,  Source
symplekin9605-0.065-0.4633Yes
87HDAC2HDAC2
Entrez,  Source
histone deacetylase 29619-0.066-0.4600Yes
88HNRPKHNRPK
Entrez,  Source
heterogeneous nuclear ribonucleoprotein K9627-0.066-0.4563Yes
89HDAC6HDAC6
Entrez,  Source
histone deacetylase 69766-0.070-0.4623Yes
90DDX47DDX47
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 479773-0.070-0.4583Yes
91GTF3C1GTF3C1
Entrez,  Source
general transcription factor IIIC, polypeptide 1, alpha 220kDa9814-0.071-0.4567Yes
92BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 39855-0.073-0.4551Yes
93PHF12PHF12
Entrez,  Source
PHD finger protein 129978-0.076-0.4594Yes
94MPGMPG
Entrez,  Source
N-methylpurine-DNA glycosylase10047-0.078-0.4596Yes
95MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 210054-0.078-0.4550Yes
96PTBP1PTBP1
Entrez,  Source
polypyrimidine tract binding protein 110089-0.079-0.4525Yes
97SP140SP140
Entrez,  Source
SP140 nuclear body protein10141-0.080-0.4512Yes
98TEP1TEP1
Entrez,  Source
telomerase-associated protein 110265-0.083-0.4551Yes
99NUAK2NUAK2
Entrez,  Source
NUAK family, SNF1-like kinase, 210275-0.084-0.4504Yes
100ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)10351-0.086-0.4506Yes
101HES6HES6
Entrez,  Source
hairy and enhancer of split 6 (Drosophila)10379-0.087-0.4470Yes
102LYARLYAR
Entrez,  Source
-10519-0.091-0.4517Yes
103NCOA6NCOA6
Entrez,  Source
nuclear receptor coactivator 610541-0.091-0.4474Yes
104SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310571-0.092-0.4437Yes
105PAX8PAX8
Entrez,  Source
paired box gene 810584-0.093-0.4386Yes
106RPL35RPL35
Entrez,  Source
ribosomal protein L3510613-0.094-0.4347Yes
107DDX24DDX24
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2410660-0.096-0.4320Yes
108RPL11RPL11
Entrez,  Source
ribosomal protein L1110718-0.098-0.4300Yes
109GTF2H4GTF2H4
Entrez,  Source
general transcription factor IIH, polypeptide 4, 52kDa10727-0.098-0.4243Yes
110TAF2TAF2
Entrez,  Source
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa10729-0.098-0.4180Yes
111HDAC10HDAC10
Entrez,  Source
histone deacetylase 1011193-0.116-0.4457Yes
112IMP4IMP4
Entrez,  Source
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)11201-0.116-0.4387Yes
113GTF2F1GTF2F1
Entrez,  Source
general transcription factor IIF, polypeptide 1, 74kDa11265-0.119-0.4358Yes
114TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)11266-0.119-0.4282Yes
115RPS19RPS19
Entrez,  Source
ribosomal protein S1911310-0.121-0.4236Yes
116RPP40RPP40
Entrez,  Source
ribonuclease P 40kDa subunit11331-0.122-0.4173Yes
117TDGTDG
Entrez,  Source
thymine-DNA glycosylase11393-0.124-0.4139Yes
118POLR3CPOLR3C
Entrez,  Source
polymerase (RNA) III (DNA directed) polypeptide C (62kD)11398-0.125-0.4062Yes
119TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa11410-0.125-0.3990Yes
120RPP38RPP38
Entrez,  Source
ribonuclease P/MRP 38kDa subunit11490-0.129-0.3967Yes
121PPIGPPIG
Entrez,  Source
peptidylprolyl isomerase G (cyclophilin G)11519-0.130-0.3904Yes
122DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin11541-0.131-0.3836Yes
123RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)11685-0.137-0.3855Yes
124MED4MED4
Entrez,  Source
mediator of RNA polymerase II transcription, subunit 4 homolog (S. cerevisiae)11726-0.140-0.3796Yes
125CLOCKCLOCK
Entrez,  Source
clock homolog (mouse)11770-0.143-0.3737Yes
126NOC4LNOC4L
Entrez,  Source
nucleolar complex associated 4 homolog (S. cerevisiae)11861-0.148-0.3710Yes
127RBM39RBM39
Entrez,  Source
RNA binding motif protein 3911924-0.152-0.3659Yes
128ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa11943-0.153-0.3574Yes
129NUFIP1NUFIP1
Entrez,  Source
nuclear fragile X mental retardation protein interacting protein 111965-0.155-0.3490Yes
130ACTL6AACTL6A
Entrez,  Source
actin-like 6A11977-0.156-0.3398Yes
131ARID1BARID1B
Entrez,  Source
AT rich interactive domain 1B (SWI1-like)12024-0.159-0.3331Yes
132SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 212039-0.160-0.3238Yes
133UBTFUBTF
Entrez,  Source
upstream binding transcription factor, RNA polymerase I12057-0.161-0.3147Yes
134MYBBP1AMYBBP1A
Entrez,  Source
MYB binding protein (P160) 1a12085-0.163-0.3062Yes
135NCBP1NCBP1
Entrez,  Source
nuclear cap binding protein subunit 1, 80kDa12145-0.168-0.2999Yes
136MKI67IPMKI67IP
Entrez,  Source
MKI67 (FHA domain) interacting nucleolar phosphoprotein12147-0.168-0.2892Yes
137CIRH1ACIRH1A
Entrez,  Source
cirrhosis, autosomal recessive 1A (cirhin)12177-0.170-0.2804Yes
138SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 412190-0.170-0.2704Yes
139FMR1FMR1
Entrez,  Source
fragile X mental retardation 112198-0.171-0.2599Yes
140NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)12259-0.176-0.2530Yes
141DNMT3ADNMT3A
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 alpha12263-0.177-0.2419Yes
142NAP1L3NAP1L3
Entrez,  Source
nucleosome assembly protein 1-like 312307-0.180-0.2335Yes
143SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 212332-0.182-0.2236Yes
144GNL3GNL3
Entrez,  Source
guanine nucleotide binding protein-like 3 (nucleolar)12347-0.183-0.2129Yes
145FUSIP1FUSIP1
Entrez,  Source
FUS interacting protein (serine/arginine-rich) 112534-0.203-0.2139Yes
146NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)12614-0.213-0.2062Yes
147NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 112621-0.214-0.1929Yes
148TFIP11TFIP11
Entrez,  Source
tuftelin interacting protein 1112637-0.216-0.1801Yes
149ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like12653-0.218-0.1672Yes
150DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12656-0.218-0.1533Yes
151RUVBL1RUVBL1
Entrez,  Source
RuvB-like 1 (E. coli)12667-0.220-0.1399Yes
152DDX56DDX56
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5612725-0.229-0.1294Yes
153HMGA1HMGA1
Entrez,  Source
high mobility group AT-hook 112748-0.232-0.1161Yes
154NCLNCL
Entrez,  Source
nucleolin12857-0.256-0.1079Yes
155NUP54NUP54
Entrez,  Source
nucleoporin 54kDa13079-0.318-0.1041Yes
156MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)13101-0.328-0.0846Yes
157XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)13111-0.334-0.0638Yes
158MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)13163-0.372-0.0437Yes
159APTXAPTX
Entrez,  Source
aprataxin13232-0.441-0.0204Yes
160SDAD1SDAD1
Entrez,  Source
SDA1 domain containing 113234-0.4450.0082Yes
Table: GSEA details [plain text format]



Fig 2: NUCLEAR_LUMEN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NUCLEAR_LUMEN: Random ES distribution   
Gene set null distribution of ES for NUCLEAR_LUMEN