Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | NUCLEOLUS |
| Enrichment Score (ES) | -0.5828427 |
| Normalized Enrichment Score (NES) | -1.907686 |
| Nominal p-value | 0.0022935779 |
| FDR q-value | 0.0185019 |
| FWER p-Value | 0.381 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 237 | 0.454 | 0.0586 | No |
| 2 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 2474 | 0.089 | -0.0946 | No |
| 3 | DEDD | DEDD Entrez, Source | death effector domain containing | 3513 | 0.057 | -0.1630 | No |
| 4 | EXOSC9 | EXOSC9 Entrez, Source | exosome component 9 | 4078 | 0.043 | -0.1983 | No |
| 5 | REXO4 | REXO4 Entrez, Source | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 4169 | 0.040 | -0.1982 | No |
| 6 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 4610 | 0.032 | -0.2260 | No |
| 7 | SC65 | SC65 Entrez, Source | - | 4719 | 0.030 | -0.2291 | No |
| 8 | IKBKAP | IKBKAP Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | 5226 | 0.020 | -0.2638 | No |
| 9 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 6082 | 0.004 | -0.3275 | No |
| 10 | FGF18 | FGF18 Entrez, Source | fibroblast growth factor 18 | 6246 | 0.001 | -0.3396 | No |
| 11 | KLHL7 | KLHL7 Entrez, Source | kelch-like 7 (Drosophila) | 6270 | 0.000 | -0.3413 | No |
| 12 | PNMA1 | PNMA1 Entrez, Source | paraneoplastic antigen MA1 | 6990 | -0.012 | -0.3934 | No |
| 13 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 7017 | -0.013 | -0.3932 | No |
| 14 | COIL | COIL Entrez, Source | coilin | 7869 | -0.029 | -0.4524 | No |
| 15 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9112 | -0.054 | -0.5367 | No |
| 16 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9460 | -0.062 | -0.5524 | No |
| 17 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 9513 | -0.063 | -0.5457 | No |
| 18 | DDX47 | DDX47 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 9773 | -0.070 | -0.5534 | No |
| 19 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 10054 | -0.078 | -0.5613 | No |
| 20 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10089 | -0.079 | -0.5506 | No |
| 21 | LYAR | LYAR Entrez, Source | - | 10519 | -0.091 | -0.5676 | Yes |
| 22 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 10613 | -0.094 | -0.5587 | Yes |
| 23 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 10660 | -0.096 | -0.5461 | Yes |
| 24 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 10718 | -0.098 | -0.5340 | Yes |
| 25 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 11201 | -0.116 | -0.5507 | Yes |
| 26 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11266 | -0.119 | -0.5354 | Yes |
| 27 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 11310 | -0.121 | -0.5183 | Yes |
| 28 | RPP40 | RPP40 Entrez, Source | ribonuclease P 40kDa subunit | 11331 | -0.122 | -0.4994 | Yes |
| 29 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11410 | -0.125 | -0.4842 | Yes |
| 30 | RPP38 | RPP38 Entrez, Source | ribonuclease P/MRP 38kDa subunit | 11490 | -0.129 | -0.4685 | Yes |
| 31 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11541 | -0.131 | -0.4502 | Yes |
| 32 | NOC4L | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 11861 | -0.148 | -0.4493 | Yes |
| 33 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11965 | -0.155 | -0.4311 | Yes |
| 34 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 12057 | -0.161 | -0.4108 | Yes |
| 35 | MYBBP1A | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 12085 | -0.163 | -0.3854 | Yes |
| 36 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 12147 | -0.168 | -0.3617 | Yes |
| 37 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 12177 | -0.170 | -0.3353 | Yes |
| 38 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12198 | -0.171 | -0.3081 | Yes |
| 39 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.2829 | Yes |
| 40 | SLC29A2 | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 12332 | -0.182 | -0.2577 | Yes |
| 41 | GNL3 | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 12347 | -0.183 | -0.2279 | Yes |
| 42 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12614 | -0.213 | -0.2121 | Yes |
| 43 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.1766 | Yes |
| 44 | DDX56 | DDX56 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 | 12725 | -0.229 | -0.1459 | Yes |
| 45 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.1127 | Yes |
| 46 | APTX | APTX Entrez, Source | aprataxin | 13232 | -0.441 | -0.0666 | Yes |
| 47 | SDAD1 | SDAD1 Entrez, Source | SDA1 domain containing 1 | 13234 | -0.445 | 0.0081 | Yes |
