Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PARP_KO_UP |
| Enrichment Score (ES) | 0.75636387 |
| Normalized Enrichment Score (NES) | 2.0612428 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0024418891 |
| FWER p-Value | 0.045 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TINAGL1 | TINAGL1 Entrez, Source | tubulointerstitial nephritis antigen-like 1 | 16 | 1.099 | 0.1855 | Yes |
| 2 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 21 | 1.039 | 0.3618 | Yes |
| 3 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 55 | 0.785 | 0.4927 | Yes |
| 4 | MGP | MGP Entrez, Source | matrix Gla protein | 108 | 0.644 | 0.5983 | Yes |
| 5 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 242 | 0.449 | 0.6646 | Yes |
| 6 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 484 | 0.291 | 0.6961 | Yes |
| 7 | FST | FST Entrez, Source | follistatin | 678 | 0.240 | 0.7224 | Yes |
| 8 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 834 | 0.207 | 0.7459 | Yes |
| 9 | NOV | NOV Entrez, Source | nephroblastoma overexpressed gene | 1086 | 0.172 | 0.7564 | Yes |
| 10 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 1445 | 0.139 | 0.7531 | No |
| 11 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 2598 | 0.084 | 0.6808 | No |
| 12 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 3153 | 0.067 | 0.6506 | No |
| 13 | CTTN | CTTN Entrez, Source | cortactin | 3158 | 0.067 | 0.6617 | No |
| 14 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 3188 | 0.066 | 0.6708 | No |
| 15 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 3286 | 0.063 | 0.6742 | No |
| 16 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 4578 | 0.032 | 0.5828 | No |
| 17 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 5270 | 0.019 | 0.5342 | No |
| 18 | B2M | B2M Entrez, Source | beta-2-microglobulin | 7066 | -0.014 | 0.4017 | No |
| 19 | DCN | DCN Entrez, Source | decorin | 7217 | -0.016 | 0.3932 | No |
| 20 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 7315 | -0.018 | 0.3890 | No |
| 21 | CD81 | CD81 Entrez, Source | CD81 molecule | 8032 | -0.032 | 0.3407 | No |
| 22 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | 0.2994 | No |
| 23 | EEF2 | EEF2 Entrez, Source | eukaryotic translation elongation factor 2 | 9787 | -0.070 | 0.2287 | No |
| 24 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10704 | -0.097 | 0.1764 | No |
| 25 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | 0.1421 | No |
