Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetPOD1_KO_DN
Enrichment Score (ES)0.43823233
Normalized Enrichment Score (NES)1.7860245
Nominal p-value0.0
FDR q-value0.031514164
FWER p-Value0.968
Table: GSEA Results Summary



Fig 1: Enrichment plot: POD1_KO_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CLEC14ACLEC14A
Entrez,  Source
C-type lectin domain family 14, member A02.0250.0438Yes
2VIMVIM
Entrez,  Source
vimentin71.3910.0734Yes
3ANXA1ANXA1
Entrez,  Source
annexin A1250.9950.0936Yes
4CTGFCTGF
Entrez,  Source
connective tissue growth factor370.8880.1120Yes
5SYCP3SYCP3
Entrez,  Source
synaptonemal complex protein 3480.8210.1290Yes
6RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa500.8100.1464Yes
7CRYABCRYAB
Entrez,  Source
crystallin, alpha B620.7560.1619Yes
8TACC1TACC1
Entrez,  Source
transforming, acidic coiled-coil containing protein 1800.6880.1755Yes
9LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1030.6590.1881Yes
10CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A1100.6330.2013Yes
11OSBPL5OSBPL5
Entrez,  Source
oxysterol binding protein-like 51500.5640.2105Yes
12DPYSL2DPYSL2
Entrez,  Source
dihydropyrimidinase-like 21580.5520.2219Yes
13AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)1640.5410.2333Yes
14GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 51880.5070.2425Yes
15SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase1910.4980.2531Yes
16SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 12170.4720.2613Yes
17AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 12200.4690.2713Yes
18SLCO2A1SLCO2A1
Entrez,  Source
solute carrier organic anion transporter family, member 2A12300.4590.2806Yes
19KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)2550.4370.2882Yes
20PLCL1PLCL1
Entrez,  Source
phospholipase C-like 12920.4080.2942Yes
21TSPAN2TSPAN2
Entrez,  Source
tetraspanin 23190.3840.3005Yes
22PLATPLAT
Entrez,  Source
plasminogen activator, tissue3210.3830.3087Yes
23RAPGEF5RAPGEF5
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 53310.3730.3161Yes
24MYADMMYADM
Entrez,  Source
myeloid-associated differentiation marker3320.3730.3242Yes
25RAPGEF4RAPGEF4
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 43330.3730.3323Yes
26PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)3930.3400.3351Yes
27PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 13960.3390.3423Yes
28PDLIM2PDLIM2
Entrez,  Source
PDZ and LIM domain 2 (mystique)4230.3250.3473Yes
29DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 24690.2970.3502Yes
30DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E25410.2720.3507Yes
31NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha5650.2650.3546Yes
32DNAJB4DNAJB4
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 46450.2460.3539Yes
33GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)6660.2420.3576Yes
34SPRED2SPRED2
Entrez,  Source
sprouty-related, EVH1 domain containing 26700.2420.3626Yes
35EHD3EHD3
Entrez,  Source
EH-domain containing 36760.2410.3674Yes
36MGLLMGLL
Entrez,  Source
monoglyceride lipase7180.2320.3693Yes
37FLI1FLI1
Entrez,  Source
Friend leukemia virus integration 17240.2310.3739Yes
38CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 27930.2150.3733Yes
39PCOLCEPCOLCE
Entrez,  Source
procollagen C-endopeptidase enhancer8040.2130.3771Yes
40FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)8350.2070.3793Yes
41GRM7GRM7
Entrez,  Source
glutamate receptor, metabotropic 78450.2060.3831Yes
42MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)8560.2030.3867Yes
43THBDTHBD
Entrez,  Source
thrombomodulin8770.1980.3894Yes
44IL2RGIL2RG
Entrez,  Source
interleukin 2 receptor, gamma (severe combined immunodeficiency)8790.1980.3936Yes
45SULF2SULF2
Entrez,  Source
sulfatase 28850.1970.3975Yes
46ITGA9ITGA9
Entrez,  Source
integrin, alpha 99230.1920.3988Yes
47SLC38A4SLC38A4
Entrez,  Source
solute carrier family 38, member 49440.1890.4014Yes
48OPTNOPTN
Entrez,  Source
optineurin9970.1830.4013Yes
49MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase10000.1830.4051Yes
50TSPAN8TSPAN8
Entrez,  Source
tetraspanin 810160.1800.4079Yes
51ANXA4ANXA4
Entrez,  Source
annexin A411090.1700.4045Yes
52PDE4DIPPDE4DIP
Entrez,  Source
phosphodiesterase 4D interacting protein (myomegalin)11340.1670.4062Yes
53P2RX4P2RX4
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 411510.1650.4086Yes
54PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B11570.1640.4117Yes
55SH3BP5SH3BP5
Entrez,  Source
SH3-domain binding protein 5 (BTK-associated)11840.1620.4132Yes
56TRAK2TRAK2
Entrez,  Source
trafficking protein, kinesin binding 212050.1610.4152Yes
57LMO7LMO7
Entrez,  Source
LIM domain 712190.1590.4176Yes
58ACSL4ACSL4
Entrez,  Source
acyl-CoA synthetase long-chain family member 412210.1590.4210Yes
59CTSSCTSS
Entrez,  Source
cathepsin S12640.1540.4211Yes
60RALBRALB
Entrez,  Source
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)12790.1530.4233Yes
61SOS2SOS2
Entrez,  Source
son of sevenless homolog 2 (Drosophila)13120.1490.4241Yes
62LZTFL1LZTFL1
Entrez,  Source
leucine zipper transcription factor-like 113500.1470.4244Yes
63PON2PON2
Entrez,  Source
paraoxonase 214020.1430.4236Yes
64SEC11L3SEC11L3
Entrez,  Source
SEC11-like 3 (S. cerevisiae)14160.1420.4257Yes
65PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha14230.1410.4282Yes
66ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b14270.1400.4311Yes
67TIMP3TIMP3
Entrez,  Source
TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)14450.1390.4328Yes
68CUGBP2CUGBP2
Entrez,  Source
CUG triplet repeat, RNA binding protein 215010.1350.4314Yes
69ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)15220.1330.4328Yes
70SERINC3SERINC3
Entrez,  Source
serine incorporator 315490.1320.4336Yes
71SH3GLB1SH3GLB1
Entrez,  Source
SH3-domain GRB2-like endophilin B115670.1300.4351Yes
72LEPREL1LEPREL1
Entrez,  Source
leprecan-like 115840.1290.4367Yes
73SEMA3GSEMA3G
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G17270.1210.4284Yes
74ST8SIA4ST8SIA4
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 417490.1190.4294Yes
75SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)17540.1190.4316Yes
76EFNB1EFNB1
Entrez,  Source
ephrin-B117700.1180.4330Yes
77BICD2BICD2
Entrez,  Source
bicaudal D homolog 2 (Drosophila)17940.1170.4338Yes
78ATP2A3ATP2A3
Entrez,  Source
ATPase, Ca++ transporting, ubiquitous18370.1150.4331Yes
79PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C18440.1150.4351Yes
80PROS1PROS1
Entrez,  Source
protein S (alpha)19010.1120.4332Yes
81MYO1CMYO1C
Entrez,  Source
myosin IC19080.1110.4351Yes
82TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)19140.1110.4372Yes
83TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)19320.1100.4382Yes
84PDE10APDE10A
Entrez,  Source
phosphodiesterase 10A19720.1090.4376No
85PAMCIPAMCI
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor20430.1060.4345No
86TSPAN12TSPAN12
Entrez,  Source
tetraspanin 1220910.1040.4331No
87MYO1EMYO1E
Entrez,  Source
myosin IE21170.1030.4334No
88CTTNBP2CTTNBP2
Entrez,  Source
cortactin binding protein 221190.1030.4356No
89RAP1BRAP1B
Entrez,  Source
RAP1B, member of RAS oncogene family21320.1020.4369No
90ARRB1ARRB1
Entrez,  Source
arrestin, beta 122280.0980.4317No
91TLR4TLR4
Entrez,  Source
toll-like receptor 422320.0980.4336No
92PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A23130.0950.4295No
93PPP1R2PPP1R2
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 224110.0910.4240No
94PIP5K2BPIP5K2B
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type II, beta24390.0900.4239No
95DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 624900.0880.4219No
96PRKCHPRKCH
Entrez,  Source
protein kinase C, eta25450.0860.4196No
97CALCRLCALCRL
Entrez,  Source
calcitonin receptor-like26080.0830.4167No
98FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES26230.0830.4174No
99CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator26860.0810.4143No
100ING3ING3
Entrez,  Source
inhibitor of growth family, member 326960.0800.4154No
101SLC9A3R2SLC9A3R2
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 227200.0790.4153No
102STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)27560.0780.4143No
103GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 328160.0770.4115No
104ABCA5ABCA5
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 528550.0760.4102No
105NESNES
Entrez,  Source
nestin28700.0750.4107No
106ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 228730.0750.4122No
107VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)29370.0730.4089No
108ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl29470.0730.4098No
109FOXC2FOXC2
Entrez,  Source
forkhead box C2 (MFH-1, mesenchyme forkhead 1)30270.0700.4052No
110ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)30400.0700.4058No
111CASTCAST
Entrez,  Source
calpastatin30520.0700.4065No
112LYSTLYST
Entrez,  Source
lysosomal trafficking regulator30590.0690.4075No
113AK1AK1
Entrez,  Source
adenylate kinase 131530.0670.4018No
114ODZ2ODZ2
Entrez,  Source
odz, odd Oz/ten-m homolog 2 (Drosophila)31910.0660.4004No
115COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 433200.0620.3919No
116ACBD5ACBD5
Entrez,  Source
acyl-Coenzyme A binding domain containing 533340.0620.3923No
117CLCA2CLCA2
Entrez,  Source
chloride channel, calcium activated, family member 233500.0610.3924No
118SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)33620.0610.3929No
119PARP4PARP4
Entrez,  Source
poly (ADP-ribose) polymerase family, member 434010.0600.3913No
120IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 134720.0580.3872No
121CXCR7CXCR7
Entrez,  Source
chemokine (C-X-C motif) receptor 734890.0580.3872No
122TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)35060.0570.3872No
123CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 535150.0570.3878No
124FRKFRK
Entrez,  Source
fyn-related kinase35330.0560.3877No
125PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 135610.0560.3869No
126DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)35810.0550.3866No
127SH2D4ASH2D4A
Entrez,  Source
SH2 domain containing 4A36340.0540.3838No
128HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase36390.0540.3846No
129CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 437670.0510.3759No
130YPEL5YPEL5
Entrez,  Source
yippee-like 5 (Drosophila)38800.0480.3684No
131NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 939030.0470.3677No
132GPC1GPC1
Entrez,  Source
glypican 139280.0460.3668No
133MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 139420.0460.3668No
134ATP10AATP10A
Entrez,  Source
ATPase, Class V, type 10A39850.0450.3646No
135NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)40250.0440.3625No
136TRPC1TRPC1
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 140330.0440.3629No
137INPP4AINPP4A
Entrez,  Source
inositol polyphosphate-4-phosphatase, type I, 107kDa40440.0440.3631No
138MYO1BMYO1B
Entrez,  Source
myosin IB40740.0430.3618No
139GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 242770.0380.3471No
140RAPGEF3RAPGEF3
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 342780.0380.3479No
141EPN2EPN2
Entrez,  Source
epsin 243140.0370.3460No
142NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)43870.0360.3413No
143PBX2PBX2
Entrez,  Source
pre-B-cell leukemia transcription factor 244260.0350.3391No
144LYPLA1LYPLA1
Entrez,  Source
lysophospholipase I44460.0350.3384No
145SYNPOSYNPO
Entrez,  Source
synaptopodin44650.0350.3378No
146ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)44980.0340.3360No
147RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 245020.0340.3365No
148ELTD1ELTD1
Entrez,  Source
EGF, latrophilin and seven transmembrane domain containing 145260.0330.3355No
149SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)45690.0330.3330No
150SYBL1SYBL1
Entrez,  Source
synaptobrevin-like 145910.0320.3320No
151ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 146000.0320.3321No
152TMEM23TMEM23
Entrez,  Source
transmembrane protein 2347090.0300.3245No
153MAPTMAPT
Entrez,  Source
microtubule-associated protein tau47160.0300.3246No
154GLRX2GLRX2
Entrez,  Source
glutaredoxin 248700.0270.3134No
155DDNDDN
Entrez,  Source
dendrin48900.0260.3126No
156NID1NID1
Entrez,  Source
nidogen 148910.0260.3131No
157EBF1EBF1
Entrez,  Source
early B-cell factor 149710.0250.3076No
158PLSCR4PLSCR4
Entrez,  Source
phospholipid scramblase 452300.0200.2882No
159GPSM3GPSM3
Entrez,  Source
G-protein signalling modulator 3 (AGS3-like, C. elegans)52550.0200.2867No
160PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule52640.0190.2865No
161EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 153060.0190.2838No
162BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA53090.0190.2840No
163SCN7ASCN7A
Entrez,  Source
sodium channel, voltage-gated, type VII, alpha53250.0180.2833No
164METRNLMETRNL
Entrez,  Source
meteorin, glial cell differentiation regulator-like53650.0170.2807No
165SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 155630.0130.2658No
166CTBSCTBS
Entrez,  Source
chitobiase, di-N-acetyl-56020.0130.2631No
167SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase56500.0120.2598No
168ART3ART3
Entrez,  Source
ADP-ribosyltransferase 358670.0080.2433No
169TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)58690.0080.2434No
170MPP3MPP3
Entrez,  Source
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)58820.0070.2427No
171PDE4DPDE4D
Entrez,  Source
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)58900.0070.2423No
172SIRPASIRPA
Entrez,  Source
signal-regulatory protein alpha59010.0070.2417No
173TMEM33TMEM33
Entrez,  Source
transmembrane protein 3359470.0060.2383No
174CAMK2DCAMK2D
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta59750.0060.2364No
175EHD4EHD4
Entrez,  Source
EH-domain containing 459860.0050.2357No
176CD97CD97
Entrez,  Source
CD97 molecule59950.0050.2352No
177CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta60620.0040.2302No
178ABI3ABI3
Entrez,  Source
ABI gene family, member 361090.0030.2268No
179GATA3GATA3
Entrez,  Source
GATA binding protein 361510.0020.2237No
180NOSTRINNOSTRIN
Entrez,  Source
nitric oxide synthase trafficker62590.0000.2154No
181TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)6293-0.0000.2129No
182SLC33A1SLC33A1
Entrez,  Source
solute carrier family 33 (acetyl-CoA transporter), member 16303-0.0000.2122No
183DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)6342-0.0010.2093No
184LASP1LASP1
Entrez,  Source
LIM and SH3 protein 16351-0.0010.2087No
185PTPRVPTPRV
Entrez,  Source
protein tyrosine phosphatase, receptor type, V (pseudogene)6358-0.0010.2083No
186MTM1MTM1
Entrez,  Source
myotubularin 16543-0.0050.1942No
187DLC1DLC1
Entrez,  Source
deleted in liver cancer 16645-0.0060.1866No
188MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)6652-0.0060.1863No
189PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 36678-0.0070.1845No
190GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase6723-0.0080.1813No
191CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b6744-0.0080.1799No
192LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)6756-0.0080.1792No
193TOB1TOB1
Entrez,  Source
transducer of ERBB2, 16785-0.0090.1773No
194WSB2WSB2
Entrez,  Source
WD repeat and SOCS box-containing 26832-0.0090.1739No
195TMEM30ATMEM30A
Entrez,  Source
transmembrane protein 30A6846-0.0100.1731No
196CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)6851-0.0100.1730No
197SNRKSNRK
Entrez,  Source
SNF related kinase6919-0.0110.1681No
198SPOPSPOP
Entrez,  Source
speckle-type POZ protein6946-0.0110.1664No
199CAV2CAV2
Entrez,  Source
caveolin 27012-0.0120.1616No
200GIMAP6GIMAP6
Entrez,  Source
GTPase, IMAP family member 67054-0.0130.1588No
201EDNRBEDNRB
Entrez,  Source
endothelin receptor type B7168-0.0150.1504No
202PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)7179-0.0150.1500No
203ITGB5ITGB5
Entrez,  Source
integrin, beta 57282-0.0180.1425No
204DSPDSP
Entrez,  Source
desmoplakin7304-0.0180.1413No
205TCP11L2TCP11L2
Entrez,  Source
t-complex 11 (mouse) like 27322-0.0180.1404No
206ITPKBITPKB
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase B7323-0.0180.1408No
207SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 37341-0.0190.1398No
208YIPF4YIPF4
Entrez,  Source
Yip1 domain family, member 47353-0.0190.1394No
209GPR116GPR116
Entrez,  Source
G protein-coupled receptor 1167368-0.0190.1387No
210TMEM106BTMEM106B
Entrez,  Source
transmembrane protein 106B7375-0.0190.1387No
211GALNT10GALNT10
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)7383-0.0190.1386No
212TCF21TCF21
Entrez,  Source
transcription factor 217391-0.0200.1385No
213HIP1HIP1
Entrez,  Source
huntingtin interacting protein 17430-0.0200.1360No
214SLC12A1SLC12A1
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 17514-0.0220.1301No
215GIMAP4GIMAP4
Entrez,  Source
GTPase, IMAP family member 47523-0.0220.1299No
216SPEGSPEG
Entrez,  Source
SPEG complex locus7555-0.0230.1280No
217PDE2APDE2A
Entrez,  Source
phosphodiesterase 2A, cGMP-stimulated7556-0.0230.1285No
218CENTB2CENTB2
Entrez,  Source
centaurin, beta 27595-0.0230.1261No
219RBMS1RBMS1
Entrez,  Source
RNA binding motif, single stranded interacting protein 17645-0.0240.1229No
220GYG1GYG1
Entrez,  Source
glycogenin 17679-0.0250.1209No
221NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)7707-0.0250.1193No
222NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor7733-0.0260.1180No
223PER2PER2
Entrez,  Source
period homolog 2 (Drosophila)7759-0.0270.1166No
224TSPAN5TSPAN5
Entrez,  Source
tetraspanin 57785-0.0270.1153No
225SLKSLK
Entrez,  Source
STE20-like kinase (yeast)7815-0.0280.1137No
226EMCNEMCN
Entrez,  Source
endomucin7816-0.0280.1143No
227STXBP3STXBP3
Entrez,  Source
syntaxin binding protein 37968-0.0310.1033No
228DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 17972-0.0310.1037No
229CDC73CDC73
Entrez,  Source
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)8021-0.0320.1007No
230SERINC1SERINC1
Entrez,  Source
serine incorporator 18027-0.0320.1010No
231UMODUMOD
Entrez,  Source
uromodulin (uromucoid, Tamm-Horsfall glycoprotein)8036-0.0320.1011No
232IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)8056-0.0320.1004No
233CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 38073-0.0330.0998No
234SH2B3SH2B3
Entrez,  Source
SH2B adaptor protein 38077-0.0330.1003No
235ATP7AATP7A
Entrez,  Source
ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)8081-0.0330.1008No
236ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)8134-0.0340.0975No
237TPP1TPP1
Entrez,  Source
tripeptidyl peptidase I8284-0.0370.0869No
238CBARA1CBARA1
Entrez,  Source
calcium binding atopy-related autoantigen 18308-0.0380.0859No
239WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 18375-0.0390.0817No
240PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O8433-0.0400.0782No
241MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase8458-0.0410.0772No
242PTPRJPTPRJ
Entrez,  Source
protein tyrosine phosphatase, receptor type, J8486-0.0410.0760No
243MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 28516-0.0420.0747No
244FUT11FUT11
Entrez,  Source
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)8544-0.0420.0735No
245ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 68557-0.0430.0735No
246LYSMD3LYSMD3
Entrez,  Source
LysM, putative peptidoglycan-binding, domain containing 38563-0.0430.0741No
247SLC17A5SLC17A5
Entrez,  Source
solute carrier family 17 (anion/sugar transporter), member 58572-0.0430.0744No
248CD47CD47
Entrez,  Source
CD47 molecule8623-0.0440.0715No
249PARVAPARVA
Entrez,  Source
parvin, alpha8673-0.0450.0687No
250DNAJB6DNAJB6
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 69020-0.0520.0432No
251PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 129058-0.0530.0415No
252PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide9133-0.0550.0370No
253GABRA4GABRA4
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 49152-0.0550.0368No
254SONSON
Entrez,  Source
SON DNA binding protein9229-0.0570.0322No
255LRRC33LRRC33
Entrez,  Source
leucine rich repeat containing 339279-0.0580.0296No
256ARAFARAF
Entrez,  Source
v-raf murine sarcoma 3611 viral oncogene homolog9300-0.0580.0294No
257ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 59336-0.0590.0279No
258HIVEP2HIVEP2
Entrez,  Source
human immunodeficiency virus type I enhancer binding protein 29351-0.0590.0281No
259GJA3GJA3
Entrez,  Source
gap junction protein, alpha 3, 46kDa (connexin 46)9402-0.0610.0256No
260RASA2RASA2
Entrez,  Source
RAS p21 protein activator 29408-0.0610.0265No
261CYP20A1CYP20A1
Entrez,  Source
cytochrome P450, family 20, subfamily A, polypeptide 19417-0.0610.0272No
262LPHN3LPHN3
Entrez,  Source
latrophilin 39442-0.0610.0267No
263GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 19461-0.0620.0267No
264TOP1MTTOP1MT
Entrez,  Source
topoisomerase (DNA) I, mitochondrial9508-0.0630.0245No
265WDR22WDR22
Entrez,  Source
WD repeat domain 229626-0.0660.0169No
266RIPK5RIPK5
Entrez,  Source
receptor interacting protein kinase 59667-0.0670.0153No
267NCOR1NCOR1
Entrez,  Source
nuclear receptor co-repressor 19668-0.0670.0168No
268CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)9683-0.0670.0171No
269EPHB1EPHB1
Entrez,  Source
EPH receptor B19688-0.0680.0183No
270HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 19698-0.0680.0191No
271EXOC8EXOC8
Entrez,  Source
exocyst complex component 89748-0.0690.0168No
272CRSP3CRSP3
Entrez,  Source
cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa9853-0.0720.0104No
273LNPEPLNPEP
Entrez,  Source
leucyl/cystinyl aminopeptidase9916-0.0740.0072No
274LIFRLIFR
Entrez,  Source
leukemia inhibitory factor receptor alpha9964-0.0750.0052No
275CRKCRK
Entrez,  Source
v-crk sarcoma virus CT10 oncogene homolog (avian)9974-0.0760.0062No
276STRNSTRN
Entrez,  Source
striatin, calmodulin binding protein10061-0.0780.0012No
277VPS54VPS54
Entrez,  Source
vacuolar protein sorting 54 (S. cerevisiae)10100-0.0790.0000No
278CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)10104-0.0790.0015No
279RFKRFK
Entrez,  Source
riboflavin kinase10120-0.0800.0021No
280LMBRD1LMBRD1
Entrez,  Source
LMBR1 domain containing 110226-0.082-0.0042No
281PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)10272-0.084-0.0059No
282NRP1NRP1
Entrez,  Source
neuropilin 110344-0.086-0.0095No
283BACE1BACE1
Entrez,  Source
beta-site APP-cleaving enzyme 110382-0.087-0.0104No
284KIF5BKIF5B
Entrez,  Source
kinesin family member 5B10608-0.094-0.0257No
285DSCR1L1DSCR1L1
Entrez,  Source
Down syndrome critical region gene 1-like 110644-0.095-0.0263No
286NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated10654-0.095-0.0250No
287CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10674-0.096-0.0244No
288PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit10702-0.097-0.0243No
289EP300EP300
Entrez,  Source
E1A binding protein p30010720-0.098-0.0235No
290HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed10765-0.099-0.0248No
291SERINC5SERINC5
Entrez,  Source
serine incorporator 510779-0.100-0.0236No
292EBAG9EBAG9
Entrez,  Source
estrogen receptor binding site associated, antigen, 910826-0.102-0.0249No
293RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 610893-0.105-0.0277No
294ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)10914-0.105-0.0270No
295MORF4L1MORF4L1
Entrez,  Source
mortality factor 4 like 110928-0.106-0.0257No
296TEX2TEX2
Entrez,  Source
testis expressed sequence 210972-0.107-0.0267No
297SGPP1SGPP1
Entrez,  Source
sphingosine-1-phosphate phosphatase 110985-0.108-0.0253No
298ADMADM
Entrez,  Source
adrenomedullin11063-0.110-0.0288No
299CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)11078-0.111-0.0275No
300JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)11158-0.115-0.0311No
301STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa11180-0.115-0.0302No
302IRS1IRS1
Entrez,  Source
insulin receptor substrate 111226-0.117-0.0311No
303TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)11338-0.122-0.0370No
304FABP4FABP4
Entrez,  Source
fatty acid binding protein 4, adipocyte11412-0.125-0.0399No
305ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)11435-0.126-0.0389No
306GIMAP1GIMAP1
Entrez,  Source
GTPase, IMAP family member 111455-0.127-0.0376No
307UBE2V2UBE2V2
Entrez,  Source
ubiquitin-conjugating enzyme E2 variant 211529-0.130-0.0404No
308HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)11571-0.132-0.0407No
309ZHX1ZHX1
Entrez,  Source
zinc fingers and homeoboxes 111673-0.137-0.0455No
310USP33USP33
Entrez,  Source
ubiquitin specific peptidase 3311679-0.137-0.0429No
311POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta11705-0.138-0.0419No
312TAOK1TAOK1
Entrez,  Source
TAO kinase 111735-0.140-0.0411No
313COLEC12COLEC12
Entrez,  Source
collectin sub-family member 1211746-0.141-0.0388No
314ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1511802-0.145-0.0399No
315PGGT1BPGGT1B
Entrez,  Source
protein geranylgeranyltransferase type I, beta subunit11812-0.145-0.0374No
316GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 111879-0.149-0.0393No
317PLD1PLD1
Entrez,  Source
phospholipase D1, phosphatidylcholine-specific11997-0.157-0.0449No
318KLHL5KLHL5
Entrez,  Source
kelch-like 5 (Drosophila)12040-0.160-0.0447No
319CYP4B1CYP4B1
Entrez,  Source
cytochrome P450, family 4, subfamily B, polypeptide 112050-0.161-0.0419No
320RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)12170-0.169-0.0474No
321RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 112220-0.173-0.0474No
322VEGFVEGF
Entrez,  Source
vascular endothelial growth factor12221-0.173-0.0437No
323TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2312278-0.177-0.0441No
324IL13RA1IL13RA1
Entrez,  Source
interleukin 13 receptor, alpha 112296-0.179-0.0416No
325TMOD3TMOD3
Entrez,  Source
tropomodulin 3 (ubiquitous)12480-0.196-0.0514No
326SLC12A2SLC12A2
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 212512-0.201-0.0494No
327ZFRZFR
Entrez,  Source
zinc finger RNA binding protein12532-0.202-0.0465No
328GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha12556-0.205-0.0438No
329EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)12591-0.209-0.0419No
330GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)12638-0.216-0.0408No
331WDFY1WDFY1
Entrez,  Source
WD repeat and FYVE domain containing 112735-0.230-0.0432No
332NT5ENT5E
Entrez,  Source
5'-nucleotidase, ecto (CD73)12800-0.241-0.0429No
333SAMD8SAMD8
Entrez,  Source
sterile alpha motif domain containing 812912-0.269-0.0456No
334TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein13000-0.292-0.0460No
335PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit13019-0.298-0.0409No
336PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase13038-0.305-0.0357No
337TMBIM1TMBIM1
Entrez,  Source
transmembrane BAX inhibitor motif containing 113062-0.311-0.0308No
338E2F5E2F5
Entrez,  Source
E2F transcription factor 5, p130-binding13090-0.322-0.0259No
339ARNTARNT
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator13157-0.367-0.0230No
340IFI35IFI35
Entrez,  Source
interferon-induced protein 3513161-0.371-0.0152No
341KIF1BKIF1B
Entrez,  Source
kinesin family member 1B13164-0.372-0.0073No
342UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 213213-0.421-0.0019No
343AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13284-0.5440.0045No
Table: GSEA details [plain text format]



Fig 2: POD1_KO_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POD1_KO_DN: Random ES distribution   
Gene set null distribution of ES for POD1_KO_DN