Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PROSTAGLANDIN_SYNTHESIS_REGULATION |
| Enrichment Score (ES) | 0.74015826 |
| Normalized Enrichment Score (NES) | 2.0578864 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002601718 |
| FWER p-Value | 0.05 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 25 | 0.995 | 0.2173 | Yes |
| 2 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 55 | 0.785 | 0.3880 | Yes |
| 3 | PTGER4 | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 393 | 0.340 | 0.4376 | Yes |
| 4 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 432 | 0.320 | 0.5052 | Yes |
| 5 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 484 | 0.291 | 0.5655 | Yes |
| 6 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 648 | 0.245 | 0.6073 | Yes |
| 7 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 1107 | 0.170 | 0.6103 | Yes |
| 8 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 1109 | 0.170 | 0.6476 | Yes |
| 9 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1367 | 0.146 | 0.6604 | Yes |
| 10 | PTGER2 | PTGER2 Entrez, Source | prostaglandin E receptor 2 (subtype EP2), 53kDa | 1419 | 0.141 | 0.6877 | Yes |
| 11 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 1689 | 0.123 | 0.6946 | Yes |
| 12 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 1714 | 0.122 | 0.7197 | Yes |
| 13 | PTGER1 | PTGER1 Entrez, Source | prostaglandin E receptor 1 (subtype EP1), 42kDa | 1823 | 0.116 | 0.7371 | Yes |
| 14 | TBXAS1 | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 2089 | 0.104 | 0.7402 | Yes |
| 15 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 3018 | 0.071 | 0.6860 | No |
| 16 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 3785 | 0.050 | 0.6396 | No |
| 17 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4357 | 0.037 | 0.6048 | No |
| 18 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 4649 | 0.031 | 0.5897 | No |
| 19 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5155 | 0.021 | 0.5565 | No |
| 20 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 5556 | 0.014 | 0.5294 | No |
| 21 | SCGB1A1 | SCGB1A1 Entrez, Source | secretoglobin, family 1A, member 1 (uteroglobin) | 5833 | 0.008 | 0.5105 | No |
| 22 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 5900 | 0.007 | 0.5071 | No |
| 23 | EDNRB | EDNRB Entrez, Source | endothelin receptor type B | 7168 | -0.015 | 0.4153 | No |
| 24 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 8088 | -0.033 | 0.3536 | No |
| 25 | PTGFR | PTGFR Entrez, Source | prostaglandin F receptor (FP) | 8181 | -0.035 | 0.3544 | No |
| 26 | PRL | PRL Entrez, Source | prolactin | 9231 | -0.057 | 0.2881 | No |
| 27 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 10591 | -0.093 | 0.2066 | No |
