Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.8275067 |
| Normalized Enrichment Score (NES) | 2.190139 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.2365796E-4 |
| FWER p-Value | 0.0040 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 50 | 0.810 | 0.1707 | Yes |
| 2 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 125 | 0.616 | 0.2980 | Yes |
| 3 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 136 | 0.594 | 0.4251 | Yes |
| 4 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 188 | 0.507 | 0.5306 | Yes |
| 5 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 205 | 0.482 | 0.6333 | Yes |
| 6 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 301 | 0.402 | 0.7128 | Yes |
| 7 | PLCE1 | PLCE1 Entrez, Source | phospholipase C, epsilon 1 | 396 | 0.339 | 0.7788 | Yes |
| 8 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 639 | 0.247 | 0.8138 | Yes |
| 9 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 987 | 0.184 | 0.8275 | Yes |
| 10 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 2147 | 0.102 | 0.7624 | No |
| 11 | RIC8B | RIC8B Entrez, Source | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) | 2332 | 0.094 | 0.7689 | No |
| 12 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 3423 | 0.060 | 0.6999 | No |
| 13 | GRK1 | GRK1 Entrez, Source | G protein-coupled receptor kinase 1 | 3705 | 0.052 | 0.6901 | No |
| 14 | GNG7 | GNG7 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 7 | 4166 | 0.041 | 0.6643 | No |
| 15 | RGS9 | RGS9 Entrez, Source | regulator of G-protein signalling 9 | 5873 | 0.008 | 0.5379 | No |
| 16 | GRK4 | GRK4 Entrez, Source | G protein-coupled receptor kinase 4 | 5984 | 0.005 | 0.5308 | No |
| 17 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 6012 | 0.005 | 0.5298 | No |
| 18 | RGS12 | RGS12 Entrez, Source | regulator of G-protein signalling 12 | 6660 | -0.007 | 0.4827 | No |
| 19 | RGS14 | RGS14 Entrez, Source | regulator of G-protein signalling 14 | 8231 | -0.036 | 0.3726 | No |
| 20 | GIT2 | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 8964 | -0.051 | 0.3286 | No |
